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Fibrillarin Proteins (FBL)

FBL product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. Additionally we are shipping Fibrillarin Antibodies (99) and Fibrillarin Kits (25) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FBL 2091 P22087
FBL 14113 P35550
Rat FBL FBL 292747 P22509
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Top Fibrillarin Proteins at antibodies-online.com

Showing 9 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 10 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Tetrahymena His tag   1 mg Log in to see 56 to 66 Days
$2,777.50
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 3 to 4 Days
$1,385.21
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 3 to 4 Days
$364.64
Details
Human Un-conjugated   1 μg Log in to see 6 Days
$168.54
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

FBL Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Top referenced Fibrillarin Proteins

  1. Human Fibrillarin Protein expressed in Escherichia coli (E. coli) - ABIN667216 : Amin, Matsunaga, Ma, Takata, Yokoyama, Uchiyama, Fukui: Fibrillarin, a nucleolar protein, is required for normal nuclear morphology and cellular growth in HeLa cells. in Biochemical and biophysical research communications 2007 (PubMed)
    Show all 2 references for ABIN667216

More Proteins for Fibrillarin (FBL) Interaction Partners

Fruit Fly (Drosophila melanogaster) Fibrillarin (FBL) interaction partners

  1. analysis of dietary rescue of fumble in a Drosophila model for pantothenate kinase-associated neurodegeneration

  2. Only mitochondria-targeted Fbl or human PanK2 (show PANK2 Proteins) was able to rescue fbl mutation.

Human Fibrillarin (FBL) interaction partners

  1. FBL overexpression contributes to tumorigenesis and is associated with poor survival in patients with breast cancer.

  2. NS1 (show PTPN11 Proteins) protein of the human H3N2 virus interacts primarily via the C-terminal NLS2/NoLS and to a minor extent via the N-terminal NLS1 with the main nucleolar proteins, nucleolin (show NCL Proteins), B23 (show NPM1 Proteins) and fibrillarin.

  3. p32 (show C1QBP Proteins) is a new rRNA maturation factor involved in the remodeling from pre-90S particles to pre-40S and pre-60S particles that requires the exchange of FBL for Nop52 (show RRP1 Proteins).

  4. Increased levels of exogenous BRAG2 (show IQSEC1 Proteins) in nucleoli result in redistribution of FBL to the nucleolar periphery.

  5. Our data suggest that fibrillarin would play a critical role in the maintenance of nuclear shape and cellular growth.

  6. Evidence that BIG1 and nucleolin (show NCL Proteins), but not fibrillarin, can be present with p62 (show GTF2H1 Proteins) at the nuclear envelope confirms the presence of BIG1 and nucleolin (show NCL Proteins) in dynamic molecular complexes that change in composition while moving through nuclei

  7. Data demonstrate that fibrillarin and Nop56 (show NOP56 Proteins) directly interact in vivo, and that this interaction is indispensable for the association of both proteins with the box C/D snoRNPs.

Mouse (Murine) Fibrillarin (FBL) interaction partners

  1. Analysis of the Localization of Fibrillarin and Sites of Pre-rRNA Synthesis in the Nucleolus-Like Bodies of Mouse GV Oocytes after Mild Treatment with Proteinase K

  2. SUV39h1 (show SUV39H1 Proteins) associated with HP1 beta (show CBX1 Proteins) in fibrillarin-positive nucleolar regions.

  3. Results suggest that proteasome-dependent processing of fibrillarin occurs upon mercury induction.

  4. This splicing factor (show SLU7 Proteins) was more abundant in hepatocyte nuclei of mice fed genetically-modified soybeans than in control mice.

  5. massive apoptosis was observed in early Fibrillarin(-/-) embryos, showing that fibrillarin is essential for development

Fibrillarin (FBL) Protein Profile

Protein Summary

This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin.

Gene names and symbols associated with Fibrillarin Proteins (FBL)

  • Fibrillarin (Fib)
  • fumble (fbl)
  • fibrillarin (FBL)
  • hypothetical protein (pxo1_107)
  • hypothetical protein (pxo1_122)
  • hypothetical protein (A30L)
  • hypothetical protein (B6R)
  • hypothetical protein (CAGL0K01859g)
  • fibrillarin (fbl)
  • fibrillarin (fib1)
  • fibrillarin (LmjF19.0100)
  • fibrillarin (Vdis_0309)
  • fibrillarin (Mzhil_1967)
  • fibrillarin (Fbl)
  • fibrillarin (LOC100356537)
  • AL022665 protein
  • CG5725 protein
  • CG9888 protein
  • Dmel\\CG5725 protein
  • Dmel\\CG9888 protein
  • dPANK protein
  • dPANK/Fbl protein
  • FBL protein
  • FIB protein
  • Fibri protein
  • FLRN protein
  • GCR-6 protein
  • GCR6 protein
  • MGC76139 protein
  • PANK protein
  • pen59C5 protein
  • RNU3IP1 protein
  • wu:fb37g12 protein
  • zgc:56145 protein
  • zgc:77130 protein

Protein level used designations for Fibrillarin Proteins (FBL)

fibrillarin , CG9888-PA , Fib-PA , CG5725-PA , CG5725-PB , CG5725-PC , CG5725-PD , CG5725-PE , CG5725-PF , CG5725-PG , fbl-PA , fbl-PB , fbl-PC , fbl-PD , fbl-PE , fbl-PF , fbl-PG , pantothenate kinase , hypothetical protein , 34 kDa nucleolar scleroderma antigen , 34-kD nucleolar scleroderma antigen , RNA, U3 small nucleolar interacting protein 1 , rRNA 2'-O-methyltransferase fibrillarin , nucleolar protein 1 , fb37g12

GENE ID SPECIES
37662 Drosophila melanogaster
46234 Drosophila melanogaster
456031 Pan troglodytes
700286 Macaca mulatta
3361711 Bacillus anthracis
3361726 Bacillus anthracis
1486508 Variola virus
1486562 Variola virus
2890032 Candida glabrata CBS 138
394705 Xenopus (Silurana) tropicalis
2540479 Schizosaccharomyces pombe 972h-
5651101 Leishmania major strain Friedlin
9751226 Vulcanisaeta distributa DSM 14429
10823612 Methanosalsum zhilinae DSM 4017
2091 Homo sapiens
476460 Canis lupus familiaris
538548 Bos taurus
14113 Mus musculus
292747 Rattus norvegicus
100356537 Oryctolagus cuniculus
100722585 Cavia porcellus
406275 Danio rerio
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