Fibrinogen alpha Chain Proteins (FGA)

The protein encoded by FGA is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Additionally we are shipping Fibrinogen alpha Chain Antibodies (108) and Fibrinogen alpha Chain Kits (48) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FGA 2243 P02671
FGA 14161  
FGA 361969  
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Top Fibrinogen alpha Chain Proteins at antibodies-online.com

Showing 10 out of 19 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$11,073.30
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$11,073.30
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$640.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Rat His tag   100 μg Log in to see 15 to 18 Days
$640.00
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$4,181.83
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 11 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human His tag,S tag   100 μg Log in to see 15 to 18 Days
$448.00
Details
HOST_Escherichia coli (E. coli) Cow His tag   100 μg Log in to see 15 to 18 Days
$733.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 11 to 18 Days
$639.38
Details

FGA Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
,
Rat (Rattus) ,

More Proteins for Fibrinogen alpha Chain (FGA) Interaction Partners

Human Fibrinogen alpha Chain (FGA) interaction partners

  1. Data indicate that repeated measurement after five hours showed a statistical significant difference for the fractional synthesis rate of fibrinogen but not for albumin (show ALB Proteins).

  2. Fibrinogen A alpha-chain amyloidosis appears to be an under-recognized disorder in Braga, Portugal, where we found a high frequency of the FGA p.Glu545Val variant

  3. High fibrinogen expression is associated with pancreatic carcinoma.

  4. The high preoperative peripheral serum fibrinogen level was related to poor survival in penile cancer patients, suggeting fibrinogen may serve as a powerful predictor of cancer specific survival (CSS (show CMAS Proteins)) in penile cancer patients.

  5. Q237 is rapidly crosslinked first by FXIIIa followed by Q366 and Q328. Both (15)NH4Cl and (15)N-GEE could be crosslinked to the three glutamines in alphaC (233-425) with a similar order of reactivity. No glutamine (show GFPT1 Proteins) is dependent on another to react first. Moreover, the remaining two glutamines of each mutant were both still reactive. These glutamines play distinct roles in fibrin crosslinking and clot (show TXNDC17 Proteins) architecture.

  6. The molecular characterization of two novel afibrinogenemic mutations in the fibrinogen A alpha and fibrinogen B beta chain establishes the importance of the A alpha and B beta C-terminal region for normal fibrinogen assembly and secretion.

  7. This meta-analysis results did not show significant associations between the polymorphisms in FGA and Ischemic stroke.

  8. there was a relatively high frequency of pregnancy loss in the setting of the FGA Thr312Ala polymorphism.

  9. Fibrinogen was significantly increased in pediatric patients with complicated appendicitis compared to patients with uncomplicated appendicitis or non-specific abdominal pain.

  10. No association between three single nucleotide polymorphisms in the fibrinogen alpha gene and schizophrenia.

Cow (Bovine) Fibrinogen alpha Chain (FGA) interaction partners

  1. NMR solution structure of the bovine fibrinogen alphaC-domain fragment, including residues Aalpha374-538, reveals a type-I' beta-hairpin, restricted at the base by a C423-C453 disulfide linkage and a short turn preceding C423.

Mouse (Murine) Fibrinogen alpha Chain (FGA) interaction partners

  1. cellular fibrin uptake was diminished by elimination of CCR2-expressing cells.

  2. Mice expressing a mutant form of fibrinogen cannot support fibrin formation exhibit compromised antimicrobial host defense.

  3. Data indicate RU-505 as an effective inhibitor of the beta-amyloid (Abeta)-fibrinogen interaction.

  4. Fbg deficiency was associated with enhanced hepatic expression of the transcription factor early growth response-1 (show EGR1 Proteins).

Fibrinogen alpha Chain (FGA) Protein Profile

Protein Summary

The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus.

Gene names and symbols associated with Fibrinogen alpha Chain Proteins (FGA)

  • fibrinogen alpha chain (FGA)
  • fibrinogen alpha chain (Fga)
  • Ac1873 protein
  • ENSMUSG00000059807 protein
  • Fba5e protein
  • Fib protein
  • Fib2 protein

Protein level used designations for Fibrinogen alpha Chain Proteins (FGA)

fibrinogen alpha chain , fibrinogen alpha chain-like , fibrinogen, A alpha polypeptide , fibrinogen A-alpha chain , fibrinogen, alpha polypeptide , carboxy-terminal region , fibrinogen A-alpha-chain , fibrinogen alpha subunit , fibrinogen alpha-E subunit , pre-fibrinogen alpha subunit

GENE ID SPECIES
100461464 Pongo abelii
100469401 Ailuropoda melanoleuca
100607544 Nomascus leucogenys
2243 Homo sapiens
522039 Bos taurus
14161 Mus musculus
475473 Canis lupus familiaris
100514666 Sus scrofa
361969 Rattus norvegicus
396307 Gallus gallus
100720646 Cavia porcellus
100069763 Equus caballus
100353616 Oryctolagus cuniculus
698244 Macaca mulatta
101102090 Ovis aries
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