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The protein encoded by FGB is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Additionally we are shipping Fibrinogen beta Chain Antibodies (104) and Fibrinogen beta Chain Kits (45) and many more products for this protein.
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Neutrophilic asthma patients and eosinophilic asthma patients had increased fibrinogen compared to controls.
Here we report a new B[beta] gene mutation (Fibrinogen St Kilda) identified in two Caucasian sisters with reduced fibrinogen level (1.2-1.6 g/L) during investigation for recurrent early miscarriages.
desAB fibrin binds to prothrombin (show F2 Proteins) through the Bbeta26-42 amino acid residues and the formation of such a complex causes a non-enzymatic activation of prothrombin (show F2 Proteins)
Strong positive association has been found between betatrophin, plasma fibrinogen (FBG), and insulin (show INS Proteins) resistance in non-diabetic subjects. Correlations with FBG and insulin (show INS Proteins) resistance were diminished in type 2 diabetes subjects.
The study reports two novel mutations detected in the FGA (show FGA Proteins) and FGB genes in two patients with inherited hypofibrinogenemia.
These experiments demonstrate, for the FGB-p.Asp185Asn mutation, a pathogenic mechanism not common for fibrinogen deficiencies, i.e. the hyperglycosylation of the Bbeta chain due to the introduction of a novel N-glycosylation motif.
High plasma fibrinogen levels and platelet count are associated with esophageal squamous cell carcinoma.
An analysis of the results obtained in this study and a critical review of previously published data indicate that gene polymorphisms in FGA (show FGA Proteins) and FGB are not related to ischemic stroke in children
Results suggest that FGB -148 C/T and -854 G/A polymorphisms probably contribute to susceptibility of ischemic stroke in Chinese population.
The results of the meta-analysis indicate that the -455 G>A polymorphism in the beta-fibrinogen gene is a susceptibility marker of ischemic cerebral infarction in the Chinese population.
Data suggest that the interaction between Abeta and fibrinogen may be an important contributor to the vascular abnormalities found in Alzheimer's disease.
beta(3) integrin, thrombin (show F2 Proteins), and Ca(2 (show CA2 Proteins)+) play critical roles in platelet aggregation without fibrinogen or VWF (show VWF Proteins)
Data suggest the potential compensatory role of fibrinogen in restoring coagulation function in vivo after hemorrhagic shock.
The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.
fibrinogen beta chain
, fibrinogen, beta chain
, B fibrinopeptide
, fibrinogen beta chain-like
, fibrinogen, B beta polypeptide
, B beta polypeptide
, fibrinogen, beta polypeptide
, liver regeneration-related protein LRRG036/LRRG043/LRRG189