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The protein encoded by FGG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Additionally we are shipping Fibrinogen gamma Chain Kits (20) and Fibrinogen gamma Chain Proteins (16) and many more products for this protein.
Showing 10 out of 148 products:
Human Polyclonal FGG Primary Antibody for EIA, WB - ABIN452999
Sie, Isaacs, de Maat, Mattace-Raso, Uitterlinden, Kardys, Hofman, Hoeks, Reneman, van Duijn, Witteman: Genetic variation in the fibrinogen-alpha and fibrinogen-gamma genes in relation to arterial stiffness: the Rotterdam Study. in Journal of hypertension 2009
Show all 3 references for ABIN452999
Human Monoclonal FGG Primary Antibody for EIA, IF - ABIN1107231
Stephens, Sahimi: Distribution of fracture strengths in disordered continua. in Physical review. B, Condensed matter 1999
Show all 2 references for ABIN1107231
Human Monoclonal FGG Primary Antibody for EIA, IF - ABIN1107232
Brueckner: Solar physics in the VUV: the importance of high resolution observations. in Applied optics 2010
Show all 2 references for ABIN1107232
Human Monoclonal FGG Primary Antibody for ICC, ELISA - ABIN969141
Uitte de Willige, Standeven, Philippou, Ariëns: The pleiotropic role of the fibrinogen gamma' chain in hemostasis. in Blood 2009
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Human Monoclonal FGG Primary Antibody for ICC, FACS - ABIN969142
Bowley, Okumura, Lord: Impaired protofibril formation in fibrinogen gamma N308K is due to altered D:D and "A:a" interactions. in Biochemistry 2009
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Human Polyclonal FGG Primary Antibody for EIA, WB - ABIN453006
Nowak-Göttl, Weiler, Hernandez, Thedieck, Seehafer, Schulte, Stoll: Fibrinogen alpha and gamma genes and factor VLeiden in children with thromboembolism: results from 2 family-based association studies. in Blood 2009
Show all 2 references for ABIN453006
Chicken Polyclonal FGG Primary Antibody for IHC, WB - ABIN2781808
Jood, Danielson, Ladenvall, Blomstrand, Jern: Fibrinogen gene variation and ischemic stroke. in Journal of thrombosis and haemostasis : JTH 2008
Chicken Polyclonal FGG Primary Antibody for WB - ABIN2781809
Uitte DE Willige, Doggen, DE Visser, Bertina, Rosendaal: Haplotypes of the fibrinogen gamma gene do not affect the risk of myocardial infarction. in Journal of thrombosis and haemostasis : JTH 2006
congenital dysfibrinogenemia with a novel mutation in fibrinogen gamma chain (gamma322 Phe-->Ile, Fibrinogen Beijing) and haemophilia B in a family
5877G>A mutation in the exon 8 of the FGG gene is underlies the pathogenesis of congenital dysfibrinogenemia in a Chinese family.
Thrombin (show F2 Antibodies) and fibrinogen gamma' regulate protofibril packing within fibrin fibers and thereby influence clot (show TXNDC17 Antibodies) stiffness.
Case Reports: clustering of mutations causing fibrinogen storage disease in the fibrinogen gamma chain between residues 284 and 375.
Data indicate that mutations of the fibrinogen (Fg) gene seem to aggregate to the D region of fibrinogen gamma chain (FGG)
Letter/Case Report: FGG 320Asp-Glu (show DCTN1 Antibodies) substitution that displayed both a quantitative and functional defect and presented as hypodysfibrinogenaemia.
Low FI levels are strongly associated with rare CFI (show CFI Antibodies) variants and age-related macular degeneration.
Report role of gamma'-fibrinogen in control of hemostatic clot (show TXNDC17 Antibodies) growth in the venous circulation.
Letter/Case Report: FGG 339CysSer mutation causes only hypofibrinogenaemia. Accompanying functionality change is due to increased sialylation and inheritance of the B448Lys allele.
Suggest gamma' fibrinogen concentrations reflect general inflammation that accompanies and may contribute to atherosclerotic CVD, instead of gamma' fibrinogen being a causal risk factor.
Data suggest the potential compensatory role of fibrinogen in restoring coagulation function in vivo after hemorrhagic shock.
Fibrinogen from mice harboring the Fibgamma390-396A mutation exhibited reduced binding to FXIII, and plasma from these mice exhibited delayed FXIII activation and fibrin crosslinking, indicating these residues mediate FXIII binding and activation.
elevated levels of gammaA/gammaA fibrinogen promote arterial thrombosis in vivo, whereas gammaA/gamma' does not
the gamma'/total fibrinogen ratio is associated with short-term outcome in ischaemic stroke
Platelet receptor engagement of the Fgg chain contributes to the stable incorporation of platelets into thrombi. Fibrinogen is internalized through alpha IIb beta 3 engagement of the Fgg chain; this interaction controls fibronectin (show FN1 Antibodies) content of platelets.
smaller thrombi result from the ability of fibrin to bind and sequester thrombin and/or the ability of the altered fibrinogen molecules, which cannot recruit platelets, to bind to and passivate the surface.
The Studies have shown that gamma chain binding to thrombin (show F2 Antibodies) and factor XIII (show UGDH Antibodies) results in clots that are mechanically stiffer and resistant to fibrinolysis, which may explain the association between gammaA/gamma' fibrinogen levels and cardiovascular disease.
the engagement of alphaIIb beta3 by the C-terminal sequence of the fibrinogen gamma-chain initiates signals that suppress subsequent fibronectin (show FN1 Antibodies) assembly by spread platelets
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.
fibrinogen, gamma chain
, fibrinogen gamma chain
, fibrinogen gamma chain-like
, fibrinogen, gamma polypeptide
, fibrinogen gamma polypeptide
, fibrinogen gamma-B chain
, fibrinogen gamma-chain
, gamma chain
, gamma polypeptide