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Fibrinogen gamma Chain Proteins (FGG)

The protein encoded by FGG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Additionally we are shipping Fibrinogen gamma Chain Antibodies (148) and Fibrinogen gamma Chain Kits (20) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FGG 2266 P02679
FGG 99571 Q8VCM7
FGG 24367 P02680
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Top Fibrinogen gamma Chain Proteins at antibodies-online.com

Showing 10 out of 16 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$732.60
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Chicken His tag 100 μg Log in to see 11 to 13 Days
$563.20
Details
Yeast Petromyzon marinus His tag   1 mg Log in to see 56 to 66 Days
$3,131.33
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$3,147.83
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,169.83
Details
HOST_Escherichia coli (E. coli) Human His tag   100 μg Log in to see 11 to 13 Days
$492.80
Details
HOST_Escherichia coli (E. coli) Rat His tag   100 μg Log in to see 11 to 13 Days
$616.00
Details

FGG Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus) ,

More Proteins for Fibrinogen gamma Chain (FGG) Interaction Partners

Human Fibrinogen gamma Chain (FGG) interaction partners

  1. Neutrophilic asthma patients and eosinophilic asthma patients had increased fibrinogen compared to controls.

  2. congenital dysfibrinogenemia with a novel mutation in fibrinogen gamma chain (gamma322 Phe-->Ile, Fibrinogen Beijing) and haemophilia B in a family

  3. 5877G>A mutation in the exon 8 of the FGG gene is underlies the pathogenesis of congenital dysfibrinogenemia in a Chinese family.

  4. Thrombin (show F2 Proteins) and fibrinogen gamma' regulate protofibril packing within fibrin fibers and thereby influence clot (show TXNDC17 Proteins) stiffness.

  5. Case Reports: clustering of mutations causing fibrinogen storage disease in the fibrinogen gamma chain between residues 284 and 375.

  6. Data indicate that mutations of the fibrinogen (Fg) gene seem to aggregate to the D region of fibrinogen gamma chain (FGG)

  7. Letter/Case Report: FGG 320Asp-Glu (show DCTN1 Proteins) substitution that displayed both a quantitative and functional defect and presented as hypodysfibrinogenaemia.

  8. Low FI levels are strongly associated with rare CFI (show CFI Proteins) variants and age-related macular degeneration.

  9. Report role of gamma'-fibrinogen in control of hemostatic clot (show TXNDC17 Proteins) growth in the venous circulation.

  10. Letter/Case Report: FGG 339CysSer mutation causes only hypofibrinogenaemia. Accompanying functionality change is due to increased sialylation and inheritance of the B448Lys allele.

Pig (Porcine) Fibrinogen gamma Chain (FGG) interaction partners

  1. Data suggest the potential compensatory role of fibrinogen in restoring coagulation function in vivo after hemorrhagic shock.

Mouse (Murine) Fibrinogen gamma Chain (FGG) interaction partners

  1. Report role of gamma'-fibrinogen in control of hemostatic clot (show TXNDC17 Proteins) growth in the venous circulation.

  2. Fibrinogen from mice harboring the Fibgamma390-396A mutation exhibited reduced binding to FXIII, and plasma from these mice exhibited delayed FXIII activation and fibrin crosslinking, indicating these residues mediate FXIII binding and activation.

  3. elevated levels of gammaA/gammaA fibrinogen promote arterial thrombosis in vivo, whereas gammaA/gamma' does not

  4. the gamma'/total fibrinogen ratio is associated with short-term outcome in ischaemic stroke

  5. Platelet receptor engagement of the Fgg chain contributes to the stable incorporation of platelets into thrombi. Fibrinogen is internalized through alpha IIb beta 3 engagement of the Fgg chain; this interaction controls fibronectin (show FN1 Proteins) content of platelets.

  6. smaller thrombi result from the ability of fibrin to bind and sequester thrombin and/or the ability of the altered fibrinogen molecules, which cannot recruit platelets, to bind to and passivate the surface.

  7. The Studies have shown that gamma chain binding to thrombin (show F2 Proteins) and factor XIII (show UGDH Proteins) results in clots that are mechanically stiffer and resistant to fibrinolysis, which may explain the association between gammaA/gamma' fibrinogen levels and cardiovascular disease.

  8. the engagement of alphaIIb beta3 by the C-terminal sequence of the fibrinogen gamma-chain initiates signals that suppress subsequent fibronectin (show FN1 Proteins) assembly by spread platelets

Fibrinogen gamma Chain (FGG) Protein Profile

Protein Summary

The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.

Gene names and symbols associated with Fibrinogen gamma Chain Proteins (FGG)

  • fibrinogen gamma chain (FGG)
  • fibrinogen gamma chain (CpipJ_CPIJ006387)
  • fibrinogen gamma chain (CpipJ_CPIJ010087)
  • fibrinogen gamma chain (fgg)
  • fibrinogen, gamma chain (LOC100220680)
  • fibrinogen gamma chain (Fgg)
  • fibrinogen, gamma polypeptide (fgg)
  • 3010002H13Rik protein
  • AI256424 protein
  • fb60h05 protein
  • fb62e01 protein
  • FGG protein
  • fibrinogen protein
  • LOC100220680 protein
  • wu:fb60h05 protein
  • wu:fb62e01 protein
  • zgc:56023 protein

Protein level used designations for Fibrinogen gamma Chain Proteins (FGG)

fibrinogen, gamma chain , fibrinogen gamma chain , gamma-fibrinogen , fibrinogen gamma chain-like , fibrinogen, gamma polypeptide , fibrinogen gamma polypeptide , fibrinogen gamma-B chain , gamma' , fibrinogen gamma-chain , gamma chain , gamma polypeptide

GENE ID SPECIES
100147221 Equus caballus
461560 Pan troglodytes
698363 Macaca mulatta
6038317 Culex quinquefasciatus
6042472 Culex quinquefasciatus
100038189 Xenopus (Silurana) tropicalis
100220680 Taeniopygia guttata
100461832 Pongo abelii
100579325 Nomascus leucogenys
2266 Homo sapiens
380331 Xenopus laevis
475474 Canis lupus familiaris
403164 Sus scrofa
280792 Bos taurus
99571 Mus musculus
24367 Rattus norvegicus
406327 Danio rerio
395837 Gallus gallus
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