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The protein encoded by FGF12 is a member of the fibroblast growth factor (FGF) family. Additionally we are shipping Fibroblast Growth Factor 12 Antibodies (51) and Fibroblast Growth Factor 12 Kits (21) and many more products for this protein.
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Dog (Canine) FGF12 Protein expressed in Escherichia coli (E. coli) - ABIN2008968
Smallwood, Munoz-Sanjuan, Tong, Macke, Hendry, Gilbert, Copeland, Jenkins, Nathans: Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development. in Proceedings of the National Academy of Sciences of the United States of America 1996
Nine SNPs of the FGF12 gene were associated with Kashin-Beck disease.
Data indicate that SCN5A (show SCN5A Proteins) variant (Nav1.5 (show SCN5A Proteins)) p.H1849R affected interaction with fibroblast growth factor homologous factor (FHFs).
Q7R-FGF12 is a disease-associated BrS mutation. Moreover, these data suggest for the first time that FHF effects on Na(+) and Ca(2 (show CA2 Proteins)+) channels are separable.
VAX1 (show VAX1 Proteins) rs10787760, rs6585429 and rs1871345 polymorphisms may be involved in nonsyndromic cleft lip with or without cleft palate in Brazilian patients, but there is no association with polymorphisms in FGF12, VCL (show VCL Proteins), or CX43 (show GJA1 Proteins)
PHOX2B (show PHOX2B Proteins), FGF12 and GAD2 (show GAD2 Proteins) genes are hypermethylated in colorectal neoplastic tissue
exogenous FGF12 can play a role in tissues by translocating into cells through the plasma membrane
Fibroblast growth factor homologous factor 1B (FHF1B) modulated the cardiac sodium channel Nav1.5 (show SCN5A Proteins).
x-ray crystal structure of FHF1b
Data describe the biophysical characterization and folding of fibroblast growth factor homologous factor-1b (FHF-1b) in comparison with acidic fibroblast growth factor (FGF-1), and show that FHF-1 is significantly more stable than FGF-1.
These findings suggest that FGF12 intracellularly suppresses radiation-induced apoptosis in mast cells independently of IB2.
results argue strongly against the possibility that FHF1 has a modulatory effect on the Na(v)1.9 sodium channel isoform in cRet (show RET Proteins)+/IB4+ neurons, but FHF1 could play a role in a distinct subset of TrkA (show NTRK1 Proteins)+/CGRP (show CALCA Proteins)+ nociceptors.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This growth factor lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.
fibroblast growth factor 12
, Fibroblast growth factor 12
, fibroblast growth factor 12B
, fibroblast growth factor FGF-12b
, fibroblast growth factor homologous factor 1
, myocyte-activating factor
, fibroblast growth factor homologous factor 1b