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anti-Fibroblast Growth Factor 14 (FGF14) Antibodies

The protein encoded by FGF14 is a member of the fibroblast growth factor (FGF) family. Additionally we are shipping FGF14 Proteins (9) and FGF14 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FGF14 2259 Q92915
FGF14 14169 P70379
FGF14 63851 Q8R5L7
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Top anti-FGF14 Antibodies at antibodies-online.com

Showing 10 out of 40 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-FGF14 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Lung 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Goat Un-conjugated EIA, WB Staining of Mouse Brain lysate using FGF14  Antibody at 1 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Mouse Goat Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$595.83
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (38.21 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit FITC IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details

FGF14 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against FGF14 Interaction Partners

Human Fibroblast Growth Factor 14 (FGF14) interaction partners

  1. study reports on a two-generation French Canadian family affected with autosomal dominant episodic ataxia (show USP14 Antibodies) caused by a frameshift mutation leading to a premature stop codon in FGF14

  2. identified the PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) pathway, the cell-cycle regulator (show CDKN2A Antibodies) Wee1 kinase (show WEE1 Antibodies), and protein kinase C (PKC (show PKC Antibodies)) as prospective regulatory nodes of neuronal excitability through modulation of the FGF14:Nav1.6 (show SCN8A Antibodies) complex.

  3. family demonstrates phenotypic variability of FGF14 deletions (SCA 27), fever sensitivity of ataxia (show USP14 Antibodies) and the added value of SNP-array analysis in making a diagnosis

  4. inhibition of GSK3 (show GSK3b Antibodies) reduces the assembly of the FGF14.Nav channel complex, modifies FGF14-dependent regulation of Na(+) currents, and induces dissociation and subcellular redistribution of the native FGF14.Nav channel complex in hippocampal neurons.

  5. THe present study demonstrates that Spinocerebellar ataxia (show USP14 Antibodies) type 27 (SCA27) caused by FGF14 mutation is rare in Chinese SCA patients.

  6. A mutation in the fibroblast growth factor 14 gene is associated with autosomal dominant cerebral ataxia (show USP14 Antibodies)

  7. A G->A variant was found in a single spinocerebellar ataxia (show USP14 Antibodies) patient in the 3' untranslated region, 31 bp to the STOP codon; it did not affect the polyadenylation site. FGF14 mutations are not a major cause of SCA in Caucasians.

  8. Frameshift mutation and polymorphisms in the fibroblast growth factor 14 gene is associated with ataxias

  9. these findings implicate FGF14 as a unique modulator of Nav channel activity in the CNS.

  10. a distinct SCA (spinocerebellar ataxia (show USP14 Antibodies))phenotype (SCA27) is associated with a F145S mutation in the fibroblast growth factor 14 (FGF14) gene on chromosome 13q34.

Mouse (Murine) Fibroblast Growth Factor 14 (FGF14) interaction partners

  1. TWEAK (show TNFSF12 Antibodies)/Fn14 (show TNFRSF12A Antibodies) pathway instrumental in the pathogenesis of spontaneous lupus nephritis

  2. FGF14 is localized in a decreasing proximal to distal gradient along the axon initial segment of Purkinje neurons.

  3. FGF14 regulates presynaptic Ca2 (show CA2 Antibodies)+ channels and synaptic transmission in cultured rat neurons.

  4. inhibition of GSK3 (show GSK3b Antibodies) reduces the assembly of the FGF14.Nav channel complex, modifies FGF14-dependent regulation of Na(+) currents, and induces dissociation and subcellular redistribution of the native FGF14.Nav channel complex in hippocampal neurons.

  5. Fgf14-deficient mice developed ataxia (show USP14 Antibodies) and a paroxysmal hyperkinetic movement disorder. FGF14 may mediate neuronal signaling, axonal trafficking and synaptosomal function.

  6. FGF14 in regulating synaptic plasticity via presynaptic mechanisms by affecting the mobilization, trafficking, or docking of synaptic vesicles to presynaptic active zones.

  7. these results suggest a role for FGF14 in certain spatial learning functions and synaptic plasticity

  8. Sodium channels in Fhf1 (show FGF12 Antibodies)-/-Fhf4-/- granule neurons inactivate at more negative membrane potential, inactivate more rapidly, and are slower to recover from the inactivated state.

  9. results suggest that FGF14 is required for normal Nav1.6 (show SCN8A Antibodies) expression in Purkinje neurons, and that the loss of FGF14 impairs spontaneous and repetitive firing in Purkinje neurons by altering the expression of Nav1.6 (show SCN8A Antibodies) channels

FGF14 Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with FGF14

  • fibroblast growth factor 14 (FGF14) antibody
  • fibroblast growth factor 14 (fgf14) antibody
  • fibroblast growth factor 14 (LOC100229510) antibody
  • fibroblast growth factor 14 (LOC100358876) antibody
  • fibroblast growth factor 14 (Fgf14) antibody
  • FGF-14 antibody
  • FGF14 antibody
  • FHF-4 antibody
  • Fhf4 antibody
  • mFHF-4(1B) antibody
  • SCA27 antibody

Protein level used designations for FGF14

fibroblast growth factor homologous factor 4 , fibroblast growth factor 14 , bA397O8.2 , FGF-14 , FGF homologus factor 4b

GENE ID SPECIES
395554 Gallus gallus
497642 Danio rerio
701077 Macaca mulatta
739338 Pan troglodytes
100217328 Xenopus (Silurana) tropicalis
100229510 Taeniopygia guttata
100358876 Oryctolagus cuniculus
2259 Homo sapiens
14169 Mus musculus
63851 Rattus norvegicus
485537 Canis lupus familiaris
615488 Bos taurus
Selected quality suppliers for anti-FGF14 (FGF14) Antibodies
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