Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression.. Additionally we are shipping FGF15 Kits (15) and FGF15 Proteins (6) and many more products for this protein.
Showing 9 out of 9 products:
This study reveals SHP (show LAMC1 Antibodies) as a global transcriptional partner of SREBP-2 (show SREBF2 Antibodies) in regulation of sterol biosynthetic gene networks and provides a potential mechanism for cholesterol-lowering action of FGF19 (show FGF19 Antibodies).
Protective effects of farnesoid X receptor (show xpr1 Antibodies) on hepatic lipid accumulation are mediated by hepatic FXR (show NR1H4 Antibodies) and are independent of intestinal FGF15 signaling.
Intestinal PPARalpha (show PPARA Antibodies)-UDP- Glucuronyltransferases and downstream FXR (show NR1H4 Antibodies)-FGF15 signalling play vital roles in control of bile acid homeostasis and the pathological development of colitis.
a direct role of intestinal FGF15/19 in the regulation of SI P450 (show POR Antibodies) expression and may have profound implications for the prediction of drug exposure in patients with compromised hepatic P450 (show POR Antibodies) function
findings implicate the brain in the antidiabetic action of systemic FGF19 (show FGF19 Antibodies) and establish the brain's capacity to rapidly, potently, and selectively increase insulin (show INS Antibodies)-independent glucose disposal
Ileal Fibroblast Growth Factor-15 (FGF15) expression was significantly reduced in Asbt (show SLC10A2 Antibodies)(-/-)apoE (show APOE Antibodies)(-/-) mice and was inversely correlated with expression of hepatic cholesterol 7-hydroxylase (Cyp7a1 (show CYP7A1 Antibodies)).
HNF4alpha (show HNF4A Antibodies) and LRH-1 (show NR5A2 Antibodies) promote active transcription histone marks on the Cyp7a1 (show CYP7A1 Antibodies) promoter that are reversed by FGF19 (show FGF19 Antibodies) in a SHP (show LAMC1 Antibodies)-dependent manner
Total ileal FGF15 expression was elevated almost 20-fold in Ostalpha (show OSTALPHA Antibodies)(-/-) mice as a result of increased villus epithelial cell number and ileocyte FGF15 protein expression
generated a variant of FGF19 (show FGF19 Antibodies), FGF19 (show FGF19 Antibodies)-7, that has altered receptor specificity with a strong bias toward FGFR1c
Differential specificity of endocrine FGF19 (show FGF19 Antibodies) and FGF21 (show FGF21 Antibodies) to FGFR1 (show FGFR1 Antibodies) and FGFR4 (show FGFR4 Antibodies) in complex with KLB (show KLB Antibodies).
Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression.
, fibroblast growth factor 15