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anti-Fibronectin Type III Domain Containing 5 (FNDC5) Antibodies

mouse homolog is linked to myoblast differentiation and development [RGD, Feb 2006].. Additionally we are shipping FNDC5 Kits (75) and FNDC5 Proteins (28) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FNDC5 252995 Q8NAU1
FNDC5 384061 Q8K4Z2
FNDC5 260327 Q8K3V5
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Top anti-FNDC5 Antibodies at antibodies-online.com

Showing 10 out of 43 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000; TMB staining; Read the data in MicroplateReader by 450 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated WB   100 μg Log in to see 5 to 8 Days
$430.50
Details
Human Rabbit PE   100 μL Log in to see 14 to 21 Days
$401.50
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$424.60
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 11 to 13 Days
$424.60
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

FNDC5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,


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Mouse (Murine) , , ,


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Rat (Rattus) , ,


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Top referenced anti-FNDC5 Antibodies

  1. Human Polyclonal FNDC5 Primary Antibody for WB - ABIN1169430 : Wrann, White, Salogiannnis, Laznik-Bogoslavski, Wu, Ma, Lin, Greenberg, Spiegelman: Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway. in Cell metabolism 2013 (PubMed)

  2. Human Polyclonal FNDC5 Primary Antibody for - ABIN1433177 : Park, Kim, Choi, Heo, Park: New role of irisin in hepatocytes: The protective effect of hepatic steatosis in vitro. in Cellular signalling 2015 (PubMed)

More Antibodies against FNDC5 Interaction Partners

Cow (Bovine) Fibronectin Type III Domain Containing 5 (FNDC5) interaction partners

  1. Neither FNDC5 nor its putatively secreted peptide irisin were found in circulation of bulls.

Human Fibronectin Type III Domain Containing 5 (FNDC5) interaction partners

  1. Crossfit training changes brain-derived neurotrophic factor (show BDNF Antibodies) and irisin levels at rest, after wingate and progressive tests, and improves aerobic capacity and body composition of young physically active men and women

  2. Data suggest that secretion of irisin by skeletal muscle is up-regulated by exercise; irisin appears to be involved in regulation of energy metabolism, insulin (show INS Antibodies) resistance, and cell differentiation. [REVIEW]

  3. Circulating irisin levels progressively decreased with the worsening of the glucose tolerance. Irisin correlated well with traditional biochemical and anthropometric parameters of metabolic health.

  4. The compositions of skeletal muscle and visceral fat play key roles in the association between circulating irisin and a patient's metabolic phenotype.

  5. Lower irisin level is associated with patients with type 2 diabetes mellitus.

  6. In patients with diabetes mellitus type 2, irisin correlated positively with insulin (show INS Antibodies) sensitivity but is not associated with beta-cell function-related variables.

  7. Irisin concentrations are associated with the presence of diabetic nephropathy and diabetic retinopathy

  8. Irisin is a myokine decreasing gradually with the progression of glucose intolerance and type 2 diabetes mellitus, and it is not correlated with body mass index in sedentary women.

  9. Plasma irisin was higher in subjects with high adipose body content (>40%) than in lean subjects. Plasma irisin was associated with metabolic syndrome.

  10. irisin alleviates endothelial dysfunction in type 2 diabetes partially via reducing oxidative stresses through inhibiting signaling pathways suggesting that irisin may be a promising molecule for the treatment of vascular complications of diabetes.

Mouse (Murine) Fibronectin Type III Domain Containing 5 (FNDC5) interaction partners

  1. irisin does not function through inflammatory NFKB activation like other myokines (such as TNFalpha (show TNF Antibodies)).

  2. Muscle FNDC5 mRNA expression and irisin release are not IL-15 (show IL15 Antibodies)-dependent in mice.

  3. irisin alleviates endothelial dysfunction in type 2 diabetes partially via reducing oxidative stresses through inhibiting signaling pathways suggesting that irisin may be a promising molecule for the treatment of vascular complications of diabetes.

  4. HFD induced obese mice showed decreased irisin secretion from adipose tissues, which might contribute to muscle insulin (show INS Antibodies) resistance.

  5. Our study also suggests the existence of irisin-specific receptor on the membrane of H9C2 cells. In conclusion, irisin in a certain concentration rage (show AGER Antibodies) increased myocardial cell metabolism, inhibited cell proliferation and promoted cell differentiation

  6. In summary, these results suggested that the endothelium-dependent relaxation of irisin is mediated by the nitric oxide (NO)-guanosine 3', 5'-cyclic phosphate (cGMP)-dependent pathway.

  7. Fndc5 facilitates neural differentiation. This effect might be related to increased expression of BDNF (show BDNF Antibodies) following overexpression of Fndc5.

  8. This study used irisin radiolabeled with (125)I and small-animal SPECT/CT imaging to investigate the metabolic elimination and distribution of irisin in vivo.

  9. High intensity exercise results in increased expression of Fndc5 in skeletal muscle.

  10. Increase PGC-1alpha (show PPARGC1A Antibodies) expression during cardiac precursor cells formation stage via rosiglitazone treatment increase FNDC5 and mitochondrial markers transcript levels which enhanced cardiac differentiation efficiency.

FNDC5 Antigen Profile

Protein Summary

mouse homolog is linked to myoblast differentiation and development

Gene names and symbols associated with FNDC5

  • fibronectin type III domain containing 5 (FNDC5) antibody
  • fibronectin type III domain containing 5 (Fndc5) antibody
  • fibronectin type III domain containing 5b (fndc5b) antibody
  • 1500001L03Rik antibody
  • AI836596 antibody
  • C87088 antibody
  • fndc5 antibody
  • FRCP2 antibody
  • irisin antibody
  • PeP antibody
  • Pxp antibody
  • si:dkey-264p5.1 antibody
  • zgc:158684 antibody

Protein level used designations for FNDC5

fibronectin type III domain-containing protein 5 , fibronectin type III domain containing 5 , fibronectin type III repeat-containing protein 2 , peroxisomal protein

GENE ID SPECIES
419667 Gallus gallus
487302 Canis lupus familiaris
538905 Bos taurus
746970 Pan troglodytes
252995 Homo sapiens
384061 Mus musculus
260327 Rattus norvegicus
100726842 Cavia porcellus
101104971 Ovis aries
555635 Danio rerio
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