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anti-Fibronectin Type III Domain Containing 5 (FNDC5) Antibodies

mouse homolog is linked to myoblast differentiation and development [RGD, Feb 2006].. Additionally we are shipping FNDC5 Kits (56) and FNDC5 Proteins (27) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FNDC5 252995 Q8NAU1
FNDC5 384061 Q8K4Z2
FNDC5 260327 Q8K3V5
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Top anti-FNDC5 Antibodies at antibodies-online.com

Showing 10 out of 43 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000; TMB staining; Read the data in MicroplateReader by 450 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: FNDC5 Antibody [NBP2-14024] - Staining of human kidney shows strong cytoplasmic positivity in cells in tubules. Western Blot: Irisin/FNDC5 Antibody [NBP2-14024] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10 Lane 2: Negative control (vector only transfected HEK293T lysate) Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY406946) 0.1 mL Log in to see 8 to 11 Days
$439.69
Details
Human Rabbit PE FACS   100 μL Log in to see 14 to 21 Days
$401.50
Details
Human Rabbit Un-conjugated WB   100 μg Log in to see 5 to 8 Days
$430.50
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$424.60
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 11 to 13 Days
$424.60
Details
Human Rabbit HRP IHC (p), WB   100 μL Log in to see 14 to 21 Days
$379.50
Details
Human Rabbit FITC FACS, IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 350 FACS, IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

FNDC5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,


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Mouse (Murine) , , , ,


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Rat (Rattus) , , ,


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Top referenced anti-FNDC5 Antibodies

  1. Human Polyclonal FNDC5 Primary Antibody for IF (p), IHC (p) - ABIN1387505 : Park, Kim, Choi, Heo, Park: New role of irisin in hepatocytes: The protective effect of hepatic steatosis in vitro. in Cellular signalling 2015 (PubMed)

  2. Human Polyclonal FNDC5 Primary Antibody for IHC, IHC (p) - ABIN4327646 : Komolka, Albrecht, Schering, Brenmoehl, Hoeflich, Maak: Locus characterization and gene expression of bovine FNDC5: is the myokine irisin relevant in cattle? in PLoS ONE 2014 (PubMed)

  3. Human Polyclonal FNDC5 Primary Antibody for WB - ABIN1169430 : Wrann, White, Salogiannnis, Laznik-Bogoslavski, Wu, Ma, Lin, Greenberg, Spiegelman: Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway. in Cell metabolism 2013 (PubMed)

More Antibodies against FNDC5 Interaction Partners

Cow (Bovine) Fibronectin Type III Domain Containing 5 (FNDC5) interaction partners

  1. Neither FNDC5 nor its putatively secreted peptide irisin were found in circulation of bulls.

Human Fibronectin Type III Domain Containing 5 (FNDC5) interaction partners

  1. Increased irisin immunoreactivity in tissues obtained from breast, ovary, cervix carcinomas, and endometrial hyperplasia suggest critical role of this peptide during carcinogenesis.

  2. Behcet's disease (BD) is characterized by chronic inflammation, and low serum irisin levels in BD may be related to atherosclerosis.

  3. Circulating irisin levels are associated with a beneficial metabolic profile but not with other adipokines and not with rs726344 in our cohort. Our data suggest a potential favorable role of irisin in the regulation of metabolism.

  4. Recent findings on the PGC1alpha/FNDC5/BDNF pathway and its role in neuroprotection, and the controversial promise of the FNDC5 peptide irisin as a mediator of the positive benefits of exercise are discussed. Review.

  5. Association between FNDC5 genetic variants and proliferative diabetic retinopathy

  6. Single nucleotide polymorphisms in FNDC5 gene correlates with obesity and glucose-lipid metabolism in Saudi population.

  7. Our results suggest that serum levels of myostatin (show MSTN Antibodies) and irisin are related in patients with type 2 diabetes

  8. Serum irisin may be a protective factor against impaired beta cell function in obesity with Acanthosis nigricans

  9. Serum irisin levels and urotensin II (show UTS2 Antibodies) levels were both significantly lower in hemodialysis patients compared with healthy subjects.

  10. Partial vascular occlusion stimulates the release of irisin during resistance exercise.

Mouse (Murine) Fibronectin Type III Domain Containing 5 (FNDC5) interaction partners

  1. PGC1alpha regulates FNDC5 and its processed and secreted peptide Irisin, which has been proposed to play a critical role in energy expenditure and to promote neural differentiation of mouse embryonic stem cells. Review.

  2. it is concluding that an enhanced expression of Fndc5 in neural progenitor cells is stimulated by Zfp521 (show ZNF521 Antibodies) overexpression in these cells

  3. Irisin directly targets osteoblast, promoting osteoblast proliferation and differentiation via activating P38/ERK MAP kinase (show MAPK1 Antibodies) signaling cascades in vitro.

  4. irisin does not function through inflammatory NFKB activation like other myokines (such as TNFalpha (show TNF Antibodies)).

  5. Muscle FNDC5 mRNA expression and irisin release are not IL-15 (show IL15 Antibodies)-dependent in mice.

  6. irisin alleviates endothelial dysfunction in type 2 diabetes partially via reducing oxidative stresses through inhibiting signaling pathways suggesting that irisin may be a promising molecule for the treatment of vascular complications of diabetes.

  7. HFD induced obese mice showed decreased irisin secretion from adipose tissues, which might contribute to muscle insulin (show INS Antibodies) resistance.

  8. Our study also suggests the existence of irisin-specific receptor on the membrane of H9C2 cells. In conclusion, irisin in a certain concentration rage (show AGER Antibodies) increased myocardial cell metabolism, inhibited cell proliferation and promoted cell differentiation

  9. In summary, these results suggested that the endothelium-dependent relaxation of irisin is mediated by the nitric oxide (NO)-guanosine 3', 5'-cyclic phosphate (cGMP)-dependent pathway.

  10. Fndc5 facilitates neural differentiation. This effect might be related to increased expression of BDNF (show BDNF Antibodies) following overexpression of Fndc5.

FNDC5 Antigen Profile

Protein Summary

mouse homolog is linked to myoblast differentiation and development

Gene names and symbols associated with FNDC5

  • fibronectin type III domain containing 5 (FNDC5) antibody
  • fibronectin type III domain containing 5 (Fndc5) antibody
  • fibronectin type III domain containing 5b (fndc5b) antibody
  • 1500001L03Rik antibody
  • AI836596 antibody
  • C87088 antibody
  • fndc5 antibody
  • FRCP2 antibody
  • irisin antibody
  • PeP antibody
  • Pxp antibody
  • si:dkey-264p5.1 antibody
  • zgc:158684 antibody

Protein level used designations for FNDC5

fibronectin type III domain-containing protein 5 , fibronectin type III domain containing 5 , fibronectin type III repeat-containing protein 2 , peroxisomal protein

GENE ID SPECIES
419667 Gallus gallus
487302 Canis lupus familiaris
538905 Bos taurus
746970 Pan troglodytes
252995 Homo sapiens
384061 Mus musculus
260327 Rattus norvegicus
100726842 Cavia porcellus
101104971 Ovis aries
555635 Danio rerio
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