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Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Additionally we are shipping Fibulin 1 Kits (15) and Fibulin 1 Proteins (13) and many more products for this protein.
Showing 10 out of 89 products:
Human Polyclonal Fibulin 1 Primary Antibody for IHC (p), WB - ABIN952325
Li, McFadden, Morgan, Cui, Hu, Wan, Zeng: All-trans retinoic acid regulates the expression of the extracellular matrix protein fibulin-1 in the guinea pig sclera and human scleral fibroblasts. in Molecular vision 2010
Show all 3 references for ABIN952325
Human Polyclonal Fibulin 1 Primary Antibody for IHC, IHC (p) - ABIN4311868
Kalamarides, Stemmer-Rachamimov, Niwa-Kawakita, Chareyre, Taranchon, Han, Martinelli, Lusis, Hegedus, Gutmann, Giovannini: Identification of a progenitor cell of origin capable of generating diverse meningioma histological subtypes. in Oncogene 2011
Show all 2 references for ABIN4311868
Human Polyclonal Fibulin 1 Primary Antibody for IHC (p), WB - ABIN658593
Rose, Behm, Drgon, Johnson, Uhl: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. in Molecular medicine (Cambridge, Mass.) 2010
Show all 2 references for ABIN658593
Human Polyclonal Fibulin 1 Primary Antibody for WB - ABIN2777105
Xie, Palmsten, MacDonald, Kieran, Potenta, Vong, Kalluri: Basement membrane derived fibulin-1 and fibulin-5 function as angiogenesis inhibitors and suppress tumor growth. in Experimental biology and medicine (Maywood, N.J.) 2008
the findings indicate that Fbln1 normally suppresses proximal OFT EMT (show ITK Antibodies) preventing proximal cushion hypercellularity and blood cell accumulation.
Fbln1 is a new positive modulator of the formation of membranous bone and endochondral bone in the skull
Extracellular calumenin (show CALU Antibodies) regulates fibulin-1 to have crucial roles in ERK1/2 (show MAPK1/3 Antibodies) signaling and cell migration.
fibulin-1 regulates versican (show Vcan Antibodies)-dependent events in ventricular morphogenesis by promoting ADAMTS1 (show ADAMTS1 Antibodies) cleavage of versican (show Vcan Antibodies) leading to suppression of trabecular cardiomyocyte proliferation mediated by the ErbB2 (show ERBB2 Antibodies)-Map kinase (show MAPK1 Antibodies) pathway.
short arm region of laminin-5 gamma2 chain: structure, mechanism of processing and binding to heparin, nidogen-1 (show NID1 Antibodies), fibulin-1 and fibulin-2 (show FBLN2 Antibodies)
binding of HPV E6 protein to fibulin-1
fibulin-1 is a new regulator of ADAMTS-1 (show ADAMTS1 Antibodies)-mediated proteoglycan (show Vcan Antibodies) proteolysis and may play an important role in proteoglycan (show Vcan Antibodies) turnover in tissues where there is overlapping expression
A murine placental overgrowth phenotype is associated with elevated Fbln1 transcript levels.
Fbln1 is required for the directed migration and survival of cranial neueral crest cells contributing to the development of pharyngeal glands, craniofacial skeleton, cranial nerves, aortic arch arteries, cardiac outflow tract and cephalic blood vessels.
LDH associated positively with fibulin-1 (beta = 0.23; p < 0.001) and ROS (show ROS1 Antibodies) (beta = 0.11; p = 0.30) in blacks only with cardiovascular disease.
The procedure described is the first to our knowledge that enables a large scale purification of Fibulin-1 from human plasma.
Study identifies a novel fibulin-1D variant, named fibulin-1D', comprising 638 amino acids with molecular weight of 70.5 kDa. Fibulin-1D' lacks a secretion sequence, has a truncated N-terminus domain and binds to the intracellular domain of integrin beta1.
The purpose of this study was to develop and characterize robust quantitative assays for the emerging cardiovascular biomarker fibulin-1 and its circulating isoforms in human plasma.
Extracellular matrix biomarker, fibulin-1 and its association with soluble uPAR (show PLAUR Antibodies) in a bi-ethnic South African population
Treatment with low-dose spironolactone reduced plasma fibulin-1 levels in patients with type 2 diabetes and resistant hypertension.
fibulin-1 expression is associated with NMIBC grade and recurrence, it is epigenetically down-regulated and functions as a tumor suppressor gene and angiogenesis inhibitor in bladder cancer.
Plasma fibulin-1 is independently associated with pulse wave velocity in type 2 diabetics.
Increased levels of fibulin-1 were independently associated with higher levels of suPAR and NT-proBNP especially in patients with lower aortic valve stenosis
Mutation of fibulin-1 causes a novel syndrome involving the central nervous system and connective tissues.
hmcn2, like fibulin 1 (fbln1), another member of the fibulin family, is predominantly expressed in fin mesenchymal cells and developing somites, contrasting the strict epithelial expression of hmcn1 (show HMCN1 Antibodies).
Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3' end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants.
, fibulin 1
, BM-90/fibulin extracellular matrix glyroprotein
, basement-membrane protein 90
, fibulin 1C
, fibulin 1D