Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
The protein encoded by FLG is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. Additionally we are shipping Filaggrin Antibodies (50) and Filaggrin Proteins (5) and many more products for this protein.
Showing 6 out of 17 products:
Human Filaggrin ELISA Kit for Sandwich ELISA - ABIN423702
Weichenthal, Ruether, Schreiber, Nair, Voorhees, Schwarz, Kabelitz, Christophers, Elder, Jenisch: Filaggrin R501X and 2282del4 mutations are not associated with chronic plaque-type psoriasis in a German cohort. in The Journal of investigative dermatology 2007
Show all 2 references for ABIN423702
FGFR1OP2 (show FGFR1OP2 ELISA Kits)-FGFR1 (show FGFR1 ELISA Kits) fusion in hematopoietic stem cells induced myeloid leukemia (show BCL11A ELISA Kits) and T-cell lymphoma in a mouse model.
MiR (show MLXIP ELISA Kits)-214 was up-regulated in mesenchymal stem cells of osteoporotic mice and down-regulated during osteoblast differentiation of mesenchymal stem cells. FGFR1 (show FGFR1 ELISA Kits) is a direct target of miR (show MLXIP ELISA Kits)-214.
demonstrated that Id1 (show ID1 ELISA Kits) and E2-2 (show TCF4 ELISA Kits) are critical regulators of EPCs function in vitro. Id1 (show ID1 ELISA Kits) interacts with E2-2 (show TCF4 ELISA Kits) and relieves the E2-2 (show TCF4 ELISA Kits)-mediated repression of FGFR1 (show FGFR1 ELISA Kits) and VEGFR2 (show KDR ELISA Kits) expression to modulate EPCs functions
FGF receptor 1-mediated anosmin-1 (show KAL1 ELISA Kits) activity plays a crucial role in the continuous remodelling of the adult olfactory bulb.
Fgfr1 (show FGFR1 ELISA Kits) and Fgfr2 (show FGFR2 ELISA Kits) in the palatal and mandibular mesenchyme have roles in regulating shelf medial wall protrusion and growth of the mandible to coordinate the craniofacial tissue movements that are required for palatal shelf elevation
Data suggest that signal transduction via Fgf23 (show FGF23 ELISA Kits)/Fgfr1 (show FGFR1 ELISA Kits) and calcitriol/calcitriol receptor have opposite roles in innate immunity; Fgf23 (show FGF23 ELISA Kits) suppresses arginase-1 (show ARG1 ELISA Kits) expression in macrophages; calcitriol stimulates arginase-1 (show ARG1 ELISA Kits) expression in macrophages.
FGFR1 (show FGFR1 ELISA Kits) has dual functions to directly regulate proximal and distal tubule phosphate and calcium reabsorption, indicating a physiological role of FGFR1 (show FGFR1 ELISA Kits) signaling in both phosphate and calcium homeostasis.
Data demonstrate an essential role for FGFR1 (show FGFR1 ELISA Kits) and FGFR2 (show FGFR2 ELISA Kits) in endothelial cells for cardiac functional recovery and vascular remodeling following in vivo cardiac ischemia-reperfusion injury, without affecting the cardiac hypertrophic response.
Activation of FGFR1 (show FGFR1 ELISA Kits) is essential for the high levels of FGF23 (show FGF23 ELISA Kits) in acute and chronic experimental uremia.
Studied the protein expression of BCL2 (show BCL2 ELISA Kits), FGF-R1, and HSP70 (show HSP70 ELISA Kits) after short-time magnetic thermoablative tumor treatment using immunohistochemistry in a human BT474 breast cancer mouse xenograft model.
The levels of filaggrin, inflammatory T helper 2 polarizing cytokines (thymic stromal lymphopoietin (TSLP (show TSLP ELISA Kits)) and interleukin 33 (IL-33 (show IL33 ELISA Kits))) and chemokine (C-C motif) ligand 27 (CCL27 (show CCL27 ELISA Kits)), histological severity markers, T and dendritic cell counts in biopsies from lesional skin of severe atopic dermatitis patients with and without filaggrin mutation and healthy skin were quantified. No significant differences were found.
The imbalance between Th1 (show TH1L ELISA Kits) and Th2 polarized immune response seems to extend to Filaggrin homeostasis, through the network of Filaggrin processing enzymes.
Levels of FLG, FLG2 and SPRR3 mRNAs and proteins were reduced in AD skin.
Data suggest that the c.1360A>G (p.T454A) and c.10363G>T (p.D3455Y) mutations of the filaggrin (FLG) gene may lead to alteration of the structure and function of the FLG (show FGFR1 ELISA Kits) protein and cause ichthyosis (show LBR ELISA Kits) vulgaris in the two families.
Results show a strong association of FLG (show FGFR1 ELISA Kits) loss-of-function mutations was found with doctor-diagnosed CD and to a lesser extent also with self-reported CD, but not with respiratory symptoms or atopy.
Identify acefylline as an activator of peptidylarginine deiminase 1 and 3 in the epidermis, resulting in filaggrin deimination.
FLG (show FGFR1 ELISA Kits) has been, and still remains the major susceptibility gene in patients with AD.
Letter: Knockdown of either filaggrin or loricrin (show LOR ELISA Kits) increases the productions of interleukin (IL)-1alpha, IL-8 (show IL8 ELISA Kits), IL-18 (show IL18 ELISA Kits) and granulocyte macrophage colony-stimulating factor (show CSF2 ELISA Kits) in stratified human keratinocytes.
Supplementation with the PPARalpha (show PPARA ELISA Kits) agonist WY14643 improved the homeostasis and barrier function of filaggrin deficient skin models by normalization of the free fatty acid profile.
Filaggrin genotype does not determine the skin's threshold to UV-induced erythema.
The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris.
, basic fibroblast growth factor receptor 1
, proto-oncogene c-Fgr
, epidermal filaggrin
, Filaggrin (profilaggrin)
, keratin intermediate filament-associated protein