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anti-Filamin A, alpha (FLNA) Antibodies

The protein encoded by FLNA is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. Additionally we are shipping Filamin A Kits (33) and Filamin A Proteins (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FLNA 2316 P21333
FLNA 293860  
FLNA 192176 Q8BTM8
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Top anti-Filamin A Antibodies at antibodies-online.com

Showing 10 out of 132 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB FLNA Antibody (Y1046) (ABIN392193) western blot analysis in U251 cell line lysates (35 µg/lane).This demonstrates the FLNA antibody detected the FLNA protein (arrow). FLNA Antibody (Y1046) (ABIN392193)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated WB FLNA Antibody (ABIN1882243) western blot analysis in PC-3, rat C6 cell line lysates (35 µg/lane). This demonstrates the FLNA antibody detected the FLNA protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from 293 cells treated with EGF 200ng/ml 5', using Filamin A (Phospho-Ser2152) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using Filamin A (Phospho-Ser2152) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from 293 cells, treated with EGF 200ng/ml 5', using Filamin A (Ab-2152) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Filamin A (Ab-2152) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Anti-FLNA / FMD antibody IHC staining of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1101559 concentration 10 ug/ml. 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$566.50
Details
Human Mouse Un-conjugated IHC (p), PLA, ELISA, WB FLNA monoclonal antibody (M01), clone 4E10-1B2 Western Blot analysis of FLNA expression in HL-60 . Immunoperoxidase of monoclonal antibody to FLNA on formalin-fixed paraffin-embedded human lymphoma tissue. [antibody concentration 1.5 ug/ml] 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IP, IHC, WB Immunohistochemical analysis of Filamin A staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of Filamin A expression in HEK293T (A), SP2/0 (B), rat heart (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details

FLNA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Filamin A Antibodies

  1. Human Monoclonal Filamin A Primary Antibody for IHC (p), PLA - ABIN560922 : Valente, Logan, Mougou-Zerelli, Lee, Silhavy, Brancati, Iannicelli, Travaglini, Romani, Illi, Adams, Szymanska, Mazzotta, Lee, Tolentino, Swistun, Salpietro, Fede, Gabriel, Russ, Cibulskis, Sougnez et al.: Mutations in TMEM216 perturb ciliogenesis and cause Joubert, Meckel and related syndromes. ... in Nature genetics 2010 (PubMed)
    Show all 7 references for ABIN560922

  2. Human Monoclonal Filamin A Primary Antibody for WB - ABIN1882243 : Gorlin, Yamin, Egan, Stewart, Stossel, Kwiatkowski, Hartwig: Human endothelial actin-binding protein (ABP-280, nonmuscle filamin): a molecular leaf spring. in The Journal of cell biology 1990 (PubMed)
    Show all 6 references for ABIN1882243

  3. Human Polyclonal Filamin A Primary Antibody for FACS, IF - ABIN392193 : Maceyka, Alvarez, Milstien, Spiegel: Filamin A links sphingosine kinase 1 and sphingosine-1-phosphate receptor 1 at lamellipodia to orchestrate cell migration. in Molecular and cellular biology 2008 (PubMed)

More Antibodies against Filamin A Interaction Partners

Zebrafish Filamin A, alpha (FLNA) interaction partners

  1. Knockdown of filamin A or vimentin (show VIM Antibodies) in normal cells profoundly suppresses apical extrusion of the neighbouring transformed cells.

Fruit Fly (Drosophila melanogaster) Filamin A, alpha (FLNA) interaction partners

  1. study identifies Cher as a new target of JNK (show MAPK8 Antibodies) signaling that links cytoskeleton dynamics to tumor progression.

  2. Data indicate that during embryonic development, the expression of Filamin and Ten-m partially overlap in ectodermal cells.

  3. Filamin is required for ovarian follicle cell motility during oogenesis.

Human Filamin A, alpha (FLNA) interaction partners

  1. Filamin-A is required to mediate SSTR2 (show SSTR2 Antibodies) effects in pancreatic neuroendocrine tumours

  2. The function of different integrins is subjected to differential regulation by FLNa.

  3. FLNA functions as a positive cellular transducer linking actin polymerization to MKL1 (show MKL1 Antibodies)-SRF activity, counteracting the known repressive complex of MKL1 (show MKL1 Antibodies) and monomeric G-actin (show ACTB Antibodies).

  4. Missense substitutions in FLNA were identified in four unrelated craniosynostosis patients.

  5. studies suggest that Vpu hijacks the FLNa function in the modulation of tetherin (show BST2 Antibodies) to neutralize the antiviral factor tetherin (show BST2 Antibodies).

  6. Our interpretation of these contradictions is that truncation and/or mutation of RhoGDI2 (show ARHGDIB Antibodies) perturbs its conformation to expose a site that adventitiously binds FLNA and is not a bona-fide interaction.

  7. Extracellular sphingosine-1-phosphate activates NF-kappaB (show NFKB1 Antibodies) only in melanoma cells that lack FLNA.

  8. FLNA anchors PC2 (show KRT6B Antibodies) to the actin cytoskeleton through complex PC2 (show KRT6B Antibodies)-FLNA-actin to reduce degradation and increase stability, and possibly regulate PC2 (show KRT6B Antibodies) function in a Ca-dependent manner.

  9. These observations imply that other interactions apart from those mediated by the canonical repeat 24 dimerisation interface contribute to FLNA homodimerization and that mutations affecting this region of the protein can have broad phenotypic effects.

  10. Our results support FLNA as a new downstream effector of mTORC2 (show CRTC2 Antibodies) controlling GBM cell motility.

Pig (Porcine) Filamin A, alpha (FLNA) interaction partners

  1. filamin reduces ENaC (show SCNN1A Antibodies) channel function through direct interaction on the cell surface

Mouse (Murine) Filamin A, alpha (FLNA) interaction partners

  1. Bones lacking filamin A are protected from estrogen-mediated post-menopausal osteoporosis

  2. findings suggest a model in which filamin A local translation following axon injury controls localized HDAC5 (show HDAC5 Antibodies) activity to promote axon regeneration.

  3. Deletion of filamin A in endothelial cells aggravated myocardial infarction-induced left ventricle dysfunction and cardiac failure as a result of defective endothelial response

  4. A new signaling set, phosphatidic acid-S6K1-FLNA-actin, sheds light into the morphogenic pathway of cytoskeletal structures that are crucial for adhesion and cell locomotion during inflammation and metastasis.

  5. Filamin-A is associated with neutrophil uropod retraction.

  6. Analysis of editing in the filamin A encoding mRNA shows very high editing levels outside the nervous system; further shows FLNA editing is mainly achieved by ADAR2 (show ADARB1 Antibodies) but that in some cases ADAR1 (show ADAR Antibodies) can efficiently compensate for ADAR2 (show ADARB1 Antibodies).

  7. Filamin a, b-interacting proteins, Cfm1 and Cfm2, are essential for the formation of cartilaginous skeleton.

  8. a major function of FLNa in modulating ion channel abundance and membrane trafficking in neurons, thereby shaping their biophysical properties and function.

  9. FLNA, a large cytoskeletal actin-binding protein (show PFN1 Antibodies), physically interacts with HIF-1alpha (show HIF1A Antibodies) and promotes tumor growth and angiogenesis.

  10. coordinated interactions between actin (through FlnA) and vesicle trafficking (through Big2 (show ARFGEF2 Antibodies)-Arf (show CDKN2A Antibodies)) direct the assembly and disassembly of membrane protein complexes required for neuronal migration and neuroependymal integrity.

Filamin A (FLNA) Antigen Profile

Protein Summary

The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-Filamin A, alpha (FLNA) Antibodies

  • filamin A, alpha (actin binding protein 280) (flna) antibody
  • filamin A, alpha (FLNA) antibody
  • filamin B, like (flnbl) antibody
  • filamin A, alpha (flna) antibody
  • cheerio (cher) antibody
  • filamin A, alpha (Flna) antibody
  • filamin, alpha (Flna) antibody
  • ABP-280 antibody
  • ABPX antibody
  • cb967 antibody
  • CG3937 antibody
  • Cher antibody
  • CSBS antibody
  • CVD1 antibody
  • Dilp2 antibody
  • Dmel\\CG3937 antibody
  • F730004A14Rik antibody
  • fb98b06 antibody
  • Fil antibody
  • filamin-1 antibody
  • FLN antibody
  • FLN-A antibody
  • Fln1 antibody
  • flna antibody
  • FMD antibody
  • joy antibody
  • MGC147094 antibody
  • MNS antibody
  • NHBP antibody
  • OPD antibody
  • OPD1 antibody
  • OPD2 antibody
  • RGD1560614 antibody
  • sko antibody
  • wu:fb98b06 antibody
  • wu:fd09g03 antibody
  • wu:fd18g06 antibody
  • wu:fd49a06 antibody
  • XLVD antibody
  • XMVD antibody

Protein level used designations for anti-Filamin A, alpha (FLNA) Antibodies

fd09g03 , filamin A, alpha (actin binding protein 280) , filamin B, like , filamin A, alpha , filamin-A , CG3937-PA , CG3937-PB , CG3937-PF , CG3937-PG , CG3937-PH , CG3937-PI , CG3937-PK , CG3937-PL , CG3937-PM , CG3937-PN , Filamin-1 , Filamin-A , cher-PA , cher-PB , cher-PF , cher-PG , cher-PH , cher-PI , cher-PK , cher-PL , cher-PM , cher-PN , filamin , filamin B , filamin isoform B , filamin-240 , shi kong , actin binding protein 280 , alpha-filamin , endothelial actin-binding protein , filamin-1 , non-muscle filamin , Endothelial actin-binding protein 280) , filamin, alpha , 450 kDa protein , FLN-A , GENA 379 , actin-binding protein 280 , dilated pupils 2 , filamin A

GENE ID SPECIES
562529 Danio rerio
699524 Macaca mulatta
569979 Danio rerio
587317 Strongylocentrotus purpuratus
779840 Xenopus (Silurana) tropicalis
100137263 Papio anubis
42066 Drosophila melanogaster
100380643 Salmo salar
2316 Homo sapiens
293860 Rattus norvegicus
481084 Canis lupus familiaris
733585 Sus scrofa
281165 Bos taurus
100328754 Oryctolagus cuniculus
100725162 Cavia porcellus
395261 Gallus gallus
101120390 Ovis aries
192176 Mus musculus
Selected quality suppliers for anti-Filamin A (FLNA) Antibodies
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