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FLNC encodes one of three related filamin genes, specifically gamma filamin. Additionally we are shipping FLNC Antibodies (40) and FLNC Proteins (5) and many more products for this protein.
Showing 10 out of 29 products:
Human FLNC ELISA Kit for Sandwich ELISA - ABIN420551
Kentsis, Shulman, Ahmed, Brennan, Monuteaux, Lee, Lipsett, Paulo, Dedeoglu, Fuhlbrigge, Bachur, Bradwin, Arditi, Sundel, Newburger, Steen, Kim: Urine proteomics for discovery of improved diagnostic markers of Kawasaki disease. in EMBO molecular medicine 2013
HSPB7 (show HSPB7 ELISA Kits) is essential for maintaining muscle integrity, which is achieved through its interaction with FLNC
The data of this study presented here provide further support that FLNC, a muscle-specific protein (show TXLNB ELISA Kits), could be a potential novel player in FTD (show FTL ELISA Kits) pathogenesis.
Aciculin (show PGM5 ELISA Kits) interacts with filamin C and Xin (show XIRP1 ELISA Kits) and is essential for myofibril assembly.
KY, IGFN1 and FLNC are part of a Z-band associated protein complex likely to provide structural support to the skeletal muscle sarcomere.
filamin C may function in signal transduction or cellular migration of the myogenic progenitor cell population
These data provide the first evidence that FLNc has a crucial role in muscle development and maintenance of muscle structural integrity and suggest the presence of a TRIO-FLNc-dependent pathway in maintaining proper myotube structure.
MuRF3 (show TRIM54 ELISA Kits) has an essential role in maintaining cardiac integrity and function after acute myocardial infarction and turnover of FHL2 (show FHL2 ELISA Kits) and gamma-filamin contributes to this cardioprotective function of MuRF3 (show TRIM54 ELISA Kits)
Cbl (show CBL ELISA Kits)-associated protein provides another link between the myofibril cytoskeleton and the plasma membrane of muscle cells, and it may play a dynamic role in the regulation and maintenance of muscle structural integrity
This study therefore identifies both BAG3 (show BAG3 ELISA Kits) reduction and autophagy promotion as potential therapies for FLNC(W2710X) myofibrillar myopathy, and identifies protein insufficiency due to sequestration, compounded by impaired autophagy, as the cause.
Biallelic variants in FLNC can cause congenital dilated cardiomyopathy.
Truncating mutations in FLNC caused an overlapping phenotype of dilated and left-dominant arrhythmogenic cardiomyopathies complicated by frequent premature sudden death
a compelling evidence of the involvement of FLNC in the development of Hypertrophic Cardiomyopathy . Most of the FLNC variants were associated with mild forms ofHypertrophic Cardiomyopathy and a reduced penetrance
FLNC is a disease gene for autosomal-dominant Restrictive Cardiomyopathy and broadens the phenotype spectrum of filaminopathies.
The identification of Filamin C as a novel KCNE2 (show KCNE2 ELISA Kits) ligand not only enhances current understanding of ion channel function and regulation, but also provides valuable information about possible pathways likely to be involved in long-QT syndrome pathogenesis
Findings indicate a functional role of filamin C in cancers.
Mutations in the gene encoding the sarcomeric protein filamin C cause a new form of familial hypertrophic cardiomyopathy.
alpha2C-adrenoreceptor interaction with filamin-2
This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene.
filamin C, gamma (actin binding protein 280)
, gamma filamin
, filamin C, gamma
, ABP-280-like protein
, actin binding protein 280
, actin-binding protein 280
, actin-binding-like protein
, filamin, gamma
, ABP-L, gamma filamin
, filamin 2
, 260kDa actin-binding protein
, cgABP260 actin-binding domain