Flavin Containing Monooxygenase 3 (FMO3) ELISA Kits

Flavin-containing monooxygenases (FMO) are an important class of drug-metabolizing enzymes that catalyze the NADPH-dependent oxygenation of various nitrogen-,sulfur-, and phosphorous-containing xenobiotics such as therapeutic drugs, dietary compounds, pesticides, and other foreign compounds. Additionally we are shipping FMO3 Antibodies (82) and FMO3 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
FMO3 2328 P31513
Anti-Mouse FMO3 FMO3 14262 P97501
Anti-Rat FMO3 FMO3 84493 Q9EQ76
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Top FMO3 ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details

More ELISA Kits for FMO3 Interaction Partners

Human Flavin Containing Monooxygenase 3 (FMO3) interaction partners

  1. FMO3 Variant is associated with chronic kidney disease.

  2. Study tested the genetic effects of three FMOs genes (FMO1 (show FMO1 ELISA Kits), FMO3, and FMO6P) on nicotine dependence by performing targeted sequencing on 2,852 nicotine-dependent and nondependent smokers; identified significant association signals for gene FMO1 (show FMO1 ELISA Kits) and FMO6P

  3. The two FMO3 mutants were in close linkage disequilibrium and might play an important role in the pharmacokinetics of sulindac in Chinese healthy male volunteers.

  4. Olanzapine clearance was not affected by CYP2D6 (show CYP2D6 ELISA Kits) or FMO3 genotypes or smoking behavior as a single factor under the present conditions because olanzapine clearance is mediated by multiple enzymes involved in two major and one minor pathways

  5. Oxidative stress-responsive transcription factor NRF2 (show GABPA ELISA Kits) is not indispensable for the human hepatic Flavin-containing monooxygenase-3 (FMO3) gene expression in HepG2 cells

  6. FMO3 gene polymorphism E158K is a significant predictor of predisposition to chronic heart disease in women.

  7. FMO3 is centrally involved in the pathogenesis of atherosclerosis by regulating cholesterol metabolism and insulin (show INS ELISA Kits) resistance. [Review]

  8. FMO3 expression is increased in ob (show INS ELISA Kits)ese/insulin resistant patients.

  9. These results suggest that genetic polymorphism in the human FMO3 gene may lead to changes of drug interactions for N- or S-oxygenations of xenobiotics and endogenous substances.

  10. Effect of two-linked mutations of the FMO3 gene on itopride metabolism in Chinese healthy volunteers

Cow (Bovine) Flavin Containing Monooxygenase 3 (FMO3) interaction partners

  1. Fishy off-flavor in cow's milk is caused by a nonsense mutation (R238X) in FMO3, found to be surprisingly common (q = 0.155) in the Swedish Red and White breed of dairy cattle.

Mouse (Murine) Flavin Containing Monooxygenase 3 (FMO3) interaction partners

  1. FMO3 can contribute to the regulation of glucose metabolism in the liver by reducing lipid-induced endoplasmic reticulum stress and the expression of PEPCK (show PEPCK ELISA Kits), independently of insulin (show INS ELISA Kits) signal transduction.

  2. FMO3 is increased in obese/insulin (show INS ELISA Kits) resistant male mice and necessary for expression of FoxO1 (show FOXO1 ELISA Kits).

  3. Fmo3 expression and function plays a role in protecting the liver from acetaminophen-induced toxicity.

  4. a major role for FMO3 in modulating glucose and lipid homeostasis

  5. Report temporal changes in hepatic Fmo3 gene expression under different conditions all known to cause hepatic oxidative stress.

  6. Report selective modulation of hepatic cytochrome P450 (show CYP ELISA Kits) and flavin monooxygenase 3 expression during citrobacter rodentium infection in SCID (show PRKDC ELISA Kits) mice.

  7. The functional activity of Fmo3 was determined.

FMO3 Antigen Profile

Antigen Summary

Flavin-containing monooxygenases (FMO) are an important class of drug-metabolizing enzymes that catalyze the NADPH-dependent oxygenation of various nitrogen-,sulfur-, and phosphorous-containing xenobiotics such as therapeutic drugs, dietary compounds, pesticides, and other foreign compounds. The human FMO gene family is composed of 5 genes and multiple pseudogenes. FMO members have distinct developmental- and tissue-specific expression patterns. The expression of this FMO3 gene, the major FMO expressed in adult liver, can vary up to 20-fold between individuals. This inter-individual variation in FMO3 expression levels is likely to have significant effects on the rate at which xenobiotics are metabolised and, therefore, is of considerable interest to the pharmaceutical industry. This transmembrane protein localizes to the endoplasmic reticulum of many tissues. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene cause the disorder trimethylaminuria (TMAu) which is characterized by the accumulation and excretion of unmetabolized trimethylamine and a distinctive body odor. In healthy individuals, trimethylamine is primarily converted to the non odorous trimethylamine N-oxide.

Gene names and symbols associated with FMO3

  • flavin containing monooxygenase 3 (FMO3) antibody
  • flavin containing monooxygenase 3 (fmo3) antibody
  • flavin containing monooxygenase 3 (Fmo3) antibody
  • AW111792 antibody
  • dJ127D3.1 antibody
  • FM03 antibody
  • FMOII antibody
  • MGC107820 antibody
  • TMAU antibody

Protein level used designations for FMO3

dimethylaniline monooxygenase [N-oxide-forming] 3 , flavin containing monooxygenase 3 , FMO 3 , FMO II , FMO form 2 , dimethylaniline oxidase 3 , hepatic flavin-containing monooxygenase 3 , hepatic flavin-containing monooxygenase-3 , trimethylamine monooxygenase , flavin-containing monooxygenase 3 , FMO 1D1 , flavin-containing monooxygenase FMO3 , flavin-containing monooxygenase form 3

GENE ID SPECIES
100171678 Pongo abelii
548424 Xenopus (Silurana) tropicalis
447265 Xenopus laevis
2328 Homo sapiens
403603 Canis lupus familiaris
281167 Bos taurus
100009065 Oryctolagus cuniculus
14262 Mus musculus
84493 Rattus norvegicus
457505 Pan troglodytes
574244 Macaca mulatta
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