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anti-Flightless I Homolog (Drosophila) (FLII) Antibodies

FLII encodes a protein with a gelsolin-like actin binding domain and an N-terminal leucine-rich repeat-protein protein interaction domain. Additionally we are shipping Flightless I Homolog (Drosophila) Kits (3) and Flightless I Homolog (Drosophila) Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FLII 2314 Q13045
FLII 14248 Q9JJ28
FLII 287375  
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Top anti-Flightless I Homolog (Drosophila) Antibodies at antibodies-online.com

Showing 10 out of 30 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-FLII Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: OVCAR-3 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p) Anti-FLII / FLI antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1101558 dilution 41552 ug/ml. Anti-FLII / FLI antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1101558 dilution 41552 ug/ml. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated ICC, WB   100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated IHC (p), WB Human, Heart: Formalin-Fixed Paraffin-Embedded (FFPE) Human, Prostate: Formalin-Fixed Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated WB FLII antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated IF, WB 100 μL Log in to see 6 to 11 Days
$485.71
Details
Human Rabbit Un-conjugated IHC, ELISA   50 μL Log in to see 9 to 11 Days
$313.50
Details
Human Rabbit Un-conjugated IHC   100 μg Log in to see 11 to 16 Days
$498.14
Details
Mouse Rabbit FITC ELISA, WB   100 μg Log in to see 8 to 10 Days
$463.83
Details
Mouse Rabbit HRP ELISA, WB   100 μg Log in to see 8 to 10 Days
$463.83
Details

FLII Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,


Mouse (Murine) , ,


, ,
Rat (Rattus) , ,


Top referenced anti-Flightless I Homolog (Drosophila) Antibodies

  1. Chicken Polyclonal FLII Primary Antibody for WB - ABIN2785799 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006 (PubMed)

More Antibodies against Flightless I Homolog (Drosophila) Interaction Partners

Zebrafish Flightless I Homolog (Drosophila) (FLII) interaction partners

  1. Embryos defective in flightless I homolog (flii), which encodes for an actin-regulating protein, exhibit normal coilings at 24 hours post fertilization (hpf) that is followed by significantly slower burst swimming at 48 hpf.

Human Flightless I Homolog (Drosophila) (FLII) interaction partners

  1. These data suggest FLII as a key regulator of ERalpha-mediated transcription through its role in regulating chromatin accessibility for the binding of RNA Polymerase II and possibly other transcriptional coactivators.

  2. Flii is constitutively secreted from macrophages and fibroblasts and is present in human plasma.

  3. The mouse (Fli1 (show FLI1 Antibodies)) and human Fli1 (show FLI1 Antibodies) genes are similarly regulated by Ets (show ETS1 Antibodies) factors in T cells.

  4. Fli-I promotes the GTP-bound active Rho-mediated relief of the autoinhibition of Daam1 and mDia1. Thus, Fli-I is a novel positive regulator of Rho-induced linear actin assembly mediated by DRFs.

  5. These data suggest that Flightless-I may facilitate interaction of the p160 coactivator complex with other coactivators or coactivator complexes containing actin or actin-like proteins.

  6. The gene that was most reproducibly up-regulated by EWS (show EWSR1 Antibodies)/FLI was NR0B1 (show NR0B1 Antibodies).

  7. effect of FliI protein on actin remodelling is a vital part of cellular motility, contraction and adhesion. Exact signaling pathways and mechanisms underpinning FliI effects in wound healing are yet to be fully identified[review]

  8. These findings support a novel mechanism whereby cytosolic CaMK-II influences beta-catenin dependent gene expression through Fli-I.

  9. The interactions between MyD88 (show MYD88 Antibodies) and multiple positive and negative regulators LRRFIP2 (show LRRFIP2 Antibodies), FLAP-1 (show LRRFIP1 Antibodies), and Fliih are highly dynamic and time-course dependent in differentially regulating/modulating NF-kappa B (show NFKB1 Antibodies) signal transduction.

  10. These findings support the model that CISK phosphorylates FLII and activates nuclear receptor transcription and suggest a new cell survival signaling pathway mediated by PI 3 (show PI3 Antibodies)-kinase and CISK.

Mouse (Murine) Flightless I Homolog (Drosophila) (FLII) interaction partners

  1. P-Rex1 stimulates migration through enhancing the interaction between Rac1 and the actin-remodelling protein.

  2. Genes downstream from Flii, including TGF-beta1 (show TGFB1 Antibodies) and TGF-beta3 (show TGFB3 Antibodies), showed significantly altered expression confirming a functional effect of the Rhodamine-Flii small interfering RNA on gene expression

  3. FliI interacts with NMMIIA to promote cell extension formation, which enables collagen remodeling in fibroblasts.

  4. FLII functions in PPARgamma (show PPARG Antibodies) activation as a molecular switch to repress transcriptional activity by interrupting formation of the PPARgamma (show PPARG Antibodies)/RXRalpha (show RXRA Antibodies) complex.

  5. LRRFIP2 (show LRRFIP2 Antibodies) inhibits NLRP3 (show NLRP3 Antibodies) inflammasome activation by recruiting the caspase-1 (show CASP1 Antibodies) inhibitor Flightless-I, thus outlining a new mechanism for negative regulation of NLRP3 (show NLRP3 Antibodies) inflammasome.

  6. increasing the level of Flii in diabetic mouse wounds led to increased TLR4 (show TLR4 Antibodies) and NF- kappa B (show NFKB1 Antibodies) production. Treatment of murine diabetic wounds with neutralising antibodies to Flii led to an improvement in healing with decreased expression of TLR4 (show TLR4 Antibodies)

  7. Using a mouse model of epidermolysis bullosa acquisita, the effect of "mopping up" Flii using Flii-neutralizing antibodies before, during, and after blister formation was determined.

  8. Flii is constitutively secreted from macrophages and fibroblasts and is present in human plasma.

  9. FliI regulates cell migration through its localization to focal adhesions and its ability to cap actin filaments, which collectively affect focal adhesion maturation.

  10. Data show that mice with elevated Flii expression exhibit impaired wound healing.

Caenorhabditis elegans (C. elegans) Flightless I Homolog (Drosophila) (FLII) interaction partners

  1. fli-1 plays an important role in regulating the actin-dependent events during C. elegans development.

  2. FLI-1 controls germ line morphogenesis and rachis organization

Flightless I Homolog (Drosophila) (FLII) Antigen Profile

Protein Summary

This gene encodes a protein with a gelsolin-like actin binding domain and an N-terminal leucine-rich repeat-protein protein interaction domain. The protein is similar to a Drosophila protein involved in early embryogenesis and the structural organization of indirect flight muscle. The gene is located within the Smith-Magenis syndrome region on chromosome 17.

Gene names and symbols associated with FLII

  • flightless I homolog (Drosophila) (FLII) antibody
  • flightless I homolog (Drosophila) (flii) antibody
  • protein flightless-1 homolog (LOC100051793) antibody
  • protein flightless-1 homolog (LOC100398338) antibody
  • protein flightless-1 homolog (LOC100619473) antibody
  • protein flightless-1 homolog (LOC100640615) antibody
  • flightless 1 homolog (flii) antibody
  • flightless I homolog (Drosophila) (Flii) antibody
  • Protein FLI-1 (fli-1) antibody
  • 3632430F08Rik antibody
  • DKFZp459O043 antibody
  • FLI antibody
  • Fli1 antibody
  • flightless antibody
  • Fliih antibody
  • FLIL antibody
  • im:7141769 antibody

Protein level used designations for FLII

flightless I homolog (Drosophila) , flightless-I homolog , protein flightless-1 homolog

GENE ID SPECIES
454486 Pan troglodytes
479521 Canis lupus familiaris
514446 Bos taurus
560281 Danio rerio
585336 Strongylocentrotus purpuratus
700471 Macaca mulatta
723252 Macaca mulatta
100051793 Equus caballus
100173989 Pongo abelii
100398338 Callithrix jacchus
100475330 Ailuropoda melanoleuca
100543687 Meleagris gallopavo
100553018 Anolis carolinensis
100600354 Nomascus leucogenys
100619473 Monodelphis domestica
100640615 Amphimedon queenslandica
444748 Xenopus laevis
416515 Gallus gallus
2314 Homo sapiens
14248 Mus musculus
287375 Rattus norvegicus
176215 Caenorhabditis elegans
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