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Follicle Stimulating Hormone, beta Polypeptide Proteins (FSHB)

The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. Additionally we are shipping Follicle Stimulating Hormone, beta Polypeptide Antibodies (181) and Follicle Stimulating Hormone, beta Polypeptide Kits (10) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FSHB 14308 Q60687
FSHB 2488 P01225
FSHB 25447 P18427
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Top Follicle Stimulating Hormone, beta Polypeptide Proteins at antibodies-online.com

Showing 10 out of 28 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Wild boar His tag,GST tag 100 μg Log in to see 11 to 13 Days
$968.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Struthio camelus His tag   1 mg Log in to see 56 to 66 Days
$2,194.50
Details
Yeast Lithobates catesbeiana His tag   1 mg Log in to see 56 to 66 Days
$2,196.33
Details
Yeast Phodopus sungorus His tag   1 mg Log in to see 56 to 66 Days
$2,196.33
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,203.67
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,203.67
Details

FSHB Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , , , ,
, ,
Rat (Rattus)

More Proteins for Follicle Stimulating Hormone, beta Polypeptide (FSHB) Interaction Partners

Zebrafish Follicle Stimulating Hormone, beta Polypeptide (FSHB) interaction partners

  1. FSH (show BRD2 Proteins)-deficient zebrafish (fshb(-/-)) were surprisingly fertile in both sexes; however, the development of both the ovary and testis was significantly delayed.

  2. zfFSHbeta promoter responded to 6h of gonadotropin-releasing hormone treatment by activating calcium influx and protein kinase C (PKC), but after 24h, GnRH induction was generated by activation of extracellular-regulated kinase 1/2 and repression by PKC.

Xenopus laevis Follicle Stimulating Hormone, beta Polypeptide (FSHB) interaction partners

  1. LHbeta (show LHB Proteins) and LH-R (show LHCGR Proteins) mRNA expression might be involved in initial maturation events of gametes, at least in males, while the gradually increase of FSH-R (show FSHR Proteins) mRNA coincided with the advancing process of gamete maturation in both sexes

Rhesus Monkey Follicle Stimulating Hormone, beta Polypeptide (FSHB) interaction partners

  1. A major regulatory mechanism for FSH (show BRD2 Proteins) glycosylation involves control of beta-subunit (show POLG Proteins) N-glycosylation, possibly by inhibition of oligosaccharyl transferase. Two primate species exhibited the same all-or-none pattern of pituitary FSHbeta glycosylation.

Mouse (Murine) Follicle Stimulating Hormone, beta Polypeptide (FSHB) interaction partners

  1. Data show that estradiol or bisphenol A decreased expression of luteinizing hormone beta (Lhb (show LHB Proteins)), follicle stimulating hormone beta (Fshb), and intracellular adhesion molecule (show NCAM1 Proteins)-5 (Icam5 (show ICAM5 Proteins)) in females but only decreased expression of Icam5 (show ICAM5 Proteins) in males.

  2. GnRH (show GNRH1 Proteins) stimulation of Fshb expression is dependent on miR (show MLXIP Proteins)-132/212 and involves a SIRT1 (show SIRT1 Proteins)-FOXO1 (show FOXO1 Proteins) pathway.

  3. results suggest that FOXO1 (show FOXO1 Proteins) binding to the proximal Fshb promoter as well as FOXO1 (show FOXO1 Proteins) interaction with SMAD3 (show SMAD3 Proteins)/4 proteins may result in decreased activin induction of Fshb in gonadotropes

  4. SCGB3A2 (show SCGB3A2 Proteins) regulates FSH (show BRD2 Proteins)/LH production in the anterior pituitary lobe.

  5. Data suggest that the BMP2 (show BMP2 Proteins)-like Activin A (show INHBA Proteins)/BMP2 (show BMP2 Proteins) chimera AB215 regulates follicle stimulating hormone beta (FSHbeta) induction in LbetaT2 gonadotroph cells due to its ability to block activin A (show INHBA Proteins) signaling.

  6. Two regions of the proximal Fshb promoter (-50/-41 and -30/-21) appear to be necessary for FOXO1 (show FOXO1 Proteins) suppression of GnRH (show GNRH1 Proteins)-induced Fshb transcription.

  7. Data suggest BMP2 (bone morphogenetic protein 2 (show BMP2 Proteins)) stimulates SMAD2 (show SMAD2 Proteins)/3 signaling in gonadotrophs via Bmpr1a (bone morphogenetic protein receptor type 1A (show BMPR1A Proteins)); such signaling via SMAD3 (show SMAD3 Proteins) appears to be necessary for up-regulation of Fshb transcription.

  8. The activin A (show INHBA Proteins) signals via SMAD (show SMAD1 Proteins) proteins, but not TAK1 (show NR2C2 Proteins) or p38 (show CRK Proteins), to regulate murine and ovine Fshb transcription in gonadotrope-like cells.

  9. The insulin (show INS Proteins)/IGF signaling pathway is required for FSH (show BRD2 Proteins)-mediated Sertoli cell proliferation.

  10. FOXL2 (show FOXL2 Proteins) is required for FSH (show BRD2 Proteins) synthesis in vivo.

Human Follicle Stimulating Hormone, beta Polypeptide (FSHB) interaction partners

  1. The FSHB -211G>T variant attenuates serum FSH (show BRD2 Proteins) levels in the supraphysiological gonadotropin setting of Klinefelter syndrome

  2. 3 known FSH-action modulating SNPs (FSHB -211G/T; FSHR -29G/A, c.2039 A/G)explained together 2.3%, 1.4%, 1.0 and 1.1% of the measured variance in serum FSH, Inhibin B, testosterone and total testes volume, respectively.

  3. The combined effect of FSHB GG+FSHR (show FSHR Proteins) AA may potentiate the FSH (show BRD2 Proteins) pathway, which increases serum levels of FSH (show BRD2 Proteins) and reduces antimullerian hormone in health girls.

  4. Serum FSH (show BRD2 Proteins) levels are affected by the combination of genetic polymorphisms in FSHR (show FSHR Proteins) and FSHB

  5. Data suggest that low serum FSH (show BRD2 Proteins) levels in men with an SNP in promoter region of FSHB (-211G/T) result from reduced binding of LHX3 (LIM homeobox 3 (show LHX3 Proteins)) to FSHB promoter/response element and down-regulation of FSHB transcription in gonadotrophs.

  6. activin-regulated transcription mediated by forkhead box L2 (show FOXL2 Proteins) [review]

  7. Data indicate that neither serum inhibin B nor follicle-stimulating hormone (FSH (show BRD2 Proteins)) is a suitable surrogate for determination of sperm concentration in a semen sample.

  8. Ser680 genotype for FSHR (show FSHR Proteins) is a factor of relative resistance to FSH (show BRD2 Proteins) stimulation resulting in slightly higher FSH (show BRD2 Proteins) serum levels, thus leading to a prolonged duration of the menstrual cycle.

  9. Phenotypic consequences of FSHB -211G-->T on the hypothalamic-pituitary-ovarian axis in women.

  10. Both estradiol and progesterone uniquely modulate basal and GnRH-stimulated gonadotropin promoters without affecting cell growth.

Cow (Bovine) Follicle Stimulating Hormone, beta Polypeptide (FSHB) interaction partners

  1. Study describes generation and characterization of a new Fshb-iCre deleter strain using 4.7 kb of ovine Fshb promoter sequences driving iCre expression exclusively in the gonadotrope lineage with mice developing normally, and fertile.

  2. the novel cis (show CISH Proteins)-regulatory element generated by the c.-1539_-1538delGGinsTTAACT mutations might play an important role in repressing FSHB transcription, possibly leading to reduced fertility

  3. A 200-base region in the bovine FSHbeta 3' untranslated region downregulates reporter expression at the translational level via interactions between AREs in both the 3'UTR and transfactors.

  4. The shift in FSH (show BRD2 Proteins) isoforms toward a greater abundance of the less acidic isoforms appears to be a key component in determining the capability for producing a preovulatory rise in estradiol.

  5. The effect of a single nucleotide polymorphism of the follicle stimulating hormone beta chain on bull fertility and semen quality is reported.

Pig (Porcine) Follicle Stimulating Hormone, beta Polypeptide (FSHB) interaction partners

  1. As in vitro experiments in the present study suggested that LHX2 (show LHX2 Proteins) regulated the expression of Fshbeta, it is possible that LHX2 (show LHX2 Proteins) controls FSH (show BRD2 Proteins) synthesis at the transcriptional level.

  2. Results showed that the effects of FSHb, ESR (show ESR1 Proteins), and PRLR (show PRLR Proteins) genes were significant in the Tibet pig population, and the effective genotypes of the three genes for reproductive traits were BB, BB, and AA, respectively.

  3. LHX3 (show LHX3 Proteins) LIM homeodomain (show LHX2 Proteins) transcription factor is involved in activation of the FSH beta-subunit (show POLG Proteins) gene in the pituitary gonadotrope cell.

  4. Prop-1 (show PROP1 Proteins) participates in the regulation of FSHbeta gene

  5. A allele of FSHbeta-1 locus in all the population and FSHbeta-2 locus in pigs of the first parity had the positive effective on TNB, NBA, and WB.

Follicle Stimulating Hormone, beta Polypeptide (FSHB) Protein Profile

Protein Summary

The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. All of these glycoproteins consist of an identical alpha subunit and a hormone-specific beta subunit. This gene encodes the beta subunit of follicle-stimulating hormone. In conjunction with luteinizing hormone, follicle-stimulating hormone induces egg and sperm production. Alternative splicing results in two transcript variants encoding the same protein.

Gene names and symbols associated with FSHB

  • follicle stimulating hormone, beta polypeptide (fshb)
  • follcle-stimulating hormone beta subunit (LOC100136594)
  • follicle stimulating hormone, beta polypeptide (FSHB)
  • follicle stimulating hormone, beta polypeptide (LOC100218526)
  • follicle stimulating hormone beta (Fshb)
  • follicle stimulating hormone, beta polypeptide (Fshb)
  • FSH protein
  • FSH-beta protein
  • FSHB protein
  • Fshbeta protein
  • gthI protein
  • LOC100136594 protein
  • LOC100218526 protein

Protein level used designations for FSHB

FSH Beta , Gth I , follicle-stimulating hormone beta subunit , follitropin subunit beta , FSH beta , follcle-stimulating hormone beta subunit , follicle stimulating hormone, beta polypeptide , FSH-B , FSH-beta , follitropin beta chain , Follicle-stimulating hormone beta subunit , follicle stimulating hormone beta-subunit , follitropin, beta chain , follicle - stimulating hormone subunit beta , follicle stimulating hormone beta , follicle-stimulating hormone beta-subunit , follicle-stimulating hormone subunit beta , class 1 follicle-stimulating hormone beta polypeptide , class 2 follicle-stimulating hormone beta polypeptide , follicule stimulating hormone, beta polypeptide , follicle stimulating hormone beta subunit , follitropin beta subunit

GENE ID SPECIES
402919 Danio rerio
407843 Xenopus laevis
100136594 Oncorhynchus mykiss
374108 Gallus gallus
485428 Canis lupus familiaris
554190 Monodelphis domestica
697317 Macaca mulatta
100218526 Taeniopygia guttata
100398993 Callithrix jacchus
14308 Mus musculus
100135522 Cavia porcellus
2488 Homo sapiens
25447 Rattus norvegicus
281171 Bos taurus
100033829 Equus caballus
396895 Sus scrofa
100008946 Oryctolagus cuniculus
443387 Ovis aries
736618 Pan troglodytes
100482376 Ailuropoda melanoleuca
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