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The protein encoded by FSHR belongs to family 1 of G-protein coupled receptors. Additionally we are shipping FSHR Kits (18) and FSHR Proteins (10) and many more products for this protein.
Showing 10 out of 97 products:
Human Polyclonal FSHR Primary Antibody for ELISA, WB - ABIN560952
Ritter, Thuering, Saint Mezard, Luong-Nguyen, Seltenmeyer, Junker, Fournier, Susa, Morvan: Follicle-stimulating hormone does not impact male bone mass in vivo or human male osteoclasts in vitro. in Calcified tissue international 2008
Human Polyclonal FSHR Primary Antibody for IF, ELISA - ABIN1535604
Tilly, Aihara, Nishimori, Jia, Billig, Kowalski, Perlas, Hsueh et al.: Expression of recombinant human follicle-stimulating hormone receptor: species-specific ligand binding, signal transduction, and identification of multiple ovarian messenger ribonucleic acid ... in Endocrinology 1992
INVESTIGATION OF STAT5A (show STAT5A Antibodies), FSHR AND LHR (show LHCGR Antibodies) GENE POLYMORPHISMS IN TURKISH INDIGENOUS CATTLE BREEDS
The expression of FSHR mRNA in granulosa cells was highest in small antral follicles, then decreased significantly as follicles increased in size, and was lowest in cysts.
transfer. We conclude that variation at these loci of the FSHR gene has no significant effect on pregnancy rates in Luxi cattle.
Specific alleles of the bovine FSHR gene are associated with variations in embryo yield and in the number of unfertilised oocytes.
This study evaluated the relationships among aromatase (show CYP19A1 Antibodies), IGF-1 (show IGF1 Antibodies), IGF2R (show IGF2R Antibodies), and follicle stimulating hormone (FSH) receptor levels expressed in ovarian follicles of cattle selected for twin pregnancies.
granulosa cell clustering is accompanied by marked increases in FSHr, IGF-1r (show IGF1R Antibodies), and p450 arom (show CYP19A1 Antibodies) expression, and precedes induction and subsequent peak E2 production
Dominant follicles experience a reduction in FSH (show BRD2 Antibodies) dependence (diminished expression of FSHR), but acquire increased LH dependence (enhanced expression of LHCGR (show LHCGR Antibodies)) as they grow during the low FSH (show BRD2 Antibodies) milieu of follicular waves.
FSHR is specifically regulated through androgen receptor (show AR Antibodies) in granulosa cells
Heterozygous heifers showed a higher pregnancy rate (67 and 66% for LHR (show LHCGR Antibodies) and FSHR genes, respectively), but no significant effects were observed for the genes studied (
Data show that double mutation of follicle-stimulating hormone receptor (fshr) and luteinizing hormone receptor (lhcgr (show LHCGR Antibodies)) resulted in infertile males.
Data show for the first time in a vertebrate species that Leydig cells as well as Sertoli cells express the mRNAs for both fshr and lhcgr (show LHCGR Antibodies).
Characterization of the first functional zebrafish (Danio rerio) gonadotropic hormone I receptor (follicle stimulating hormone receptor).
The role of FSHR gene variants (SNPs in exon 10 (codon 307 and 680) and in the core promoter region (at position -29) and Ala189Val inactivating mutation) in Turkish infertile women
Ala307Thr polymorphism in FSHR can be potentially associated to primary ovarian insufficiency development and can be considered as a screening marker in patients with ovarian failure signals.
The Asn680Ser polymorphism within the FSHR gene was not associated with endometriosis and infertility.
Our studies further confirmed reports that there were no significant associations between the FSHR Thr307Ala and Asn680Ser polymorphisms and male infertility risk. However, a combined FSHR genotype showed significant association with male infertility.
Endothelial FSHR expression in breast cancer is associated with vascular remodeling at tumor periphery.
The extracellular loop 2 (EL2 (show SPTA1 Antibodies)) of FSH receptor (FSHR) plays a pivotal role in various events downstream of FSH (show BRD2 Antibodies) stimulation.
the hinge region and its adjacent domains have roles in binding and signaling patterns of the thyrotropin and follitropin receptor
This study demonstrate that the two common FSHR polymorphisms FSHR 307 and FSHR 680 affect FSH (show BRD2 Antibodies)-induced granulosa cell responses in human small antral follicles.
Girls homozygous for FSHR -29AA (reduced FSH receptor expression) entered puberty 7.4 (2.5-12.4) months later than carriers of the common variants FSHR -29GG+GA.
This is the first study to confirm the association of novel LHCGR (show LHCGR Antibodies) and FSHR SNPs with PCOS. The differential association of LHCGR (show LHCGR Antibodies) and FSHR variants with PCOS confirms the racial/ethnic contribution to their association with PCOS.
Brca1 (show BRCA1 Antibodies)(GC-/-) models reveal that specific intra-follicular Brca1 (show BRCA1 Antibodies) loss alone, or combined with cancer-promoting genetic (Trp53 (show TP53 Antibodies) loss) and endocrine (high serum follicle-stimulating hormone) changes, was not sufficient to cause ovarian tumors.
Data (including date from knockout mice) suggest that Fshr is expressed early in pregnany in placenta and other extragonadal tissues of fetoplacental unit; expression is particularly strong at term.
Sertoli cell-specific expression of MTA2 (show MTA2 Antibodies) is required for transcriptional regulation of FSHR gene during spermatogenesis.
By day 20 and in adult animals total AR or FSHR ablation significantly reduced Leydig cell numbers but Sertoli cell specific AR ablation had no effect.
The results demonstrate that gain-of-function mutations of the FSHR in mice bring about distinct and clear changes in ovarian function
haploinsufficiency of the follicle-stimulating hormone receptor accelerates oocyte loss inducing early reproductive senescence and biological aging in mice
show that FSH-R haploinsufficiency leads to a decrease in ovulation, altered ovarian steroidogenesis, and neuroendocrine impairments resulting in early reproductive senescence
the loss of FSH-R signaling alters the follicular environment, where oocyte-granulosa interactions are perturbed, creating an out-of-phase germ cell and somatic cell development
These results suggest that FSH-R signaling normally maintains water balance in Sertoli cells in addition to regulating androgen-binding protein production. (FSH receptor)
shrinkage in epididymal epithelial areas observed in follicle stimulating hormone receptor knockout mice
The amount of dopamine d1 receptor (show DRD1 Antibodies), dopamine D2 receptor (show DRD2 Antibodies), and follicle stimulating hormone receptor (FSHr) mRNA were quantified in ovarian tissues in anestrous and mares expressing estrus during the breeding season are reported.
The results showed that polymorphisms in exon 10 of the FSHR gene had a significant effect on litter size traits of Wannan Black and Berkshire pigs. These results can be applied for marker-assisted selection in the 2 swine breeds
These results showed that an increased FSHR gene expression level was accompanied with an increase in histone H3K9 acetylation levels, suggesting that histone H3K9 acetylation could regulate the expression of the porcine FSHR gene.
248 F(2) animals from a Duroc and Meishan cross were genotyped for three FSHR SNPs at positions 74, 532 and 1166, and these were correlated with the phenotypes of litter size and corpus luteum number
findings suggest the FSH receptor may be involved in the early follicle formation in pigs, which begins during prenatal life.
FSHR is expressed in the hamster ovary starting from the fetal life to account for FSH (show BRD2 Antibodies)-induced primordial follicle formation and cyclic AMP (show TMPRSS5 Antibodies) production.
The protein encoded by this gene belongs to family 1 of G-protein coupled receptors. It is the receptor for follicle stimulating hormone and functions in gonad development. Mutations in this gene cause ovarian dysgenesis type 1, and also ovarian hyperstimulation syndrome. Alternative splicing results in multiple transcript variants.
follicle stimulating hormone receptor
, follicle-stimulating hormone receptor
, gonadotropic hormone I
, follicle-stimulating hormone receptor-like
, FSH receptor
, follitropin receptor