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anti-Folliculin (FLCN) Antibodies

FLCN is located within the Smith-Magenis syndrome region on chromosome 17. Additionally we are shipping FLCN Kits (8) and FLCN Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FLCN 216805 Q8QZS3
FLCN 303185 Q76JQ2
FLCN 201163 Q8NFG4
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Top anti-FLCN Antibodies at antibodies-online.com

Showing 10 out of 82 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of FLCN Antibody (Center) in CEM cell line lysates (35ug/lane). FLCN (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-FLCN AntibodyTitration: 1.0 µg/mL  Positive Control: Fetal Heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of FLCN Antibody (C-term) Pab (ABIN652601) pre-incubated without(lane 1) and with(lane 2) blocking peptide in K562 cell line lysate. FLCN (arrow) was detected using the purified polyclonal antibody (1:250 dilution). FLCN Antibody (C-term)(ABIN652601) flow cytometric analysis of k562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (63.36 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 6 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of FLCN Antibody (Center) (ABIN652602) in CEM cell line lysates (35 µg/lane). FLCN (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lung carcinoma reacted with FLCN Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit APC ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

FLCN Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-FLCN Antibodies

  1. Human Polyclonal FLCN Primary Antibody for EIA, WB - ABIN453652 : Khoo, Giraud, Kahnoski, Chen, Motorna, Nickolov, Binet, Lambert, Friedel, Lévy, Ferlicot, Wolkenstein, Hammel, Bergerheim, Hedblad, Bradley, Teh, Nordenskjöld, Richard: Clinical and genetic studies of Birt-Hogg-Dubé syndrome. in Journal of medical genetics 2002 (PubMed)
    Show all 2 references for ABIN453652

  2. Human Polyclonal FLCN Primary Antibody for ELISA, WB - ABIN531278 : Nahorski, Reiman, Lim, Nookala, Seabra, Lu, Fenton, Boora, Nordenskjöld, Latif, Hurst, Maher: Birt Hogg-Dubé syndrome-associated FLCN mutations disrupt protein stability. in Human mutation 2011 (PubMed)

More Antibodies against FLCN Interaction Partners

Mouse (Murine) Folliculin (FLCN) interaction partners

  1. mTOR (show FRAP1 Antibodies) inhibitor, sirolimus, suppresses the tumor's growth, suggesting that mTOR (show FRAP1 Antibodies) inhibitors might be effective in control of FLCN-deficient RCC (show XRCC1 Antibodies).

  2. we show that glycogen (show GYS1 Antibodies) accumulates in kidneys from mice lacking FLCN and in renal tumors from a BHD patient

  3. Fnip1 (show FNIP1 Antibodies) and Fnip2 (show FNIP2 Antibodies) play critical roles in kidney tumor suppression in cooperation with Flcn

  4. Folliculin (Flcn) inactivation leads to murine cardiac hypertrophy through mTORC1 deregulation.

  5. The FLCN-GABARAP (show GABARAP Antibodies) association is modulated by the presence of either folliculin-interacting protein (FNIP)-1 (show FNIP1 Antibodies) or FNIP2 (show FNIP2 Antibodies) and further regulated by ULK1 (show ULK1 Antibodies).

  6. Flcn regulates apoptosis in lung epithelium via E-cadherin (show CDH1 Antibodies)-LKB1 (show STK11 Antibodies)-AMPK (show PRKAA1 Antibodies) axis.

  7. loss of FLCN constitutively activates AMPK (show PRKAA1 Antibodies), resulting in PGC-1alpha (show PPARGC1A Antibodies)-mediated mitochondrial biogenesis and increased ROS (show ROS1 Antibodies) production

  8. These data support a model in which dysregulation of the FLCN-p0071 (show PKP4 Antibodies) interaction leads to alterations in cell adhesion, cell polarity, and RhoA (show RHOA Antibodies) signaling.

  9. FLCN deficiency and subsequent increased PPARGC1A (show PPARGC1A Antibodies) expression result in increased mitochondrial function and oxidative metabolism as the source of cellular energy, which may drive hyperplastic transformation.

  10. The involvement of the AMPK (show PRKAA1 Antibodies)-MAPO1 (show FNIP2 Antibodies)-FLCN complex in the signaling pathway of apoptosis, is described.

Human Folliculin (FLCN) interaction partners

  1. We identified a hitherto unreported pathogenic FLCN frameshift deletion c.563delT (p.Phe188Serfs*35) in a family of a 46-year-old woman presented with macrohematuria due to bilateral chromophobe renal carcinomas

  2. FLCN irregulation in lung cysts of primary spontaneous pneumothorax is not associated with promoter methylation.

  3. mTOR (show FRAP1 Antibodies) inhibitor, sirolimus, suppresses the tumor's growth, suggesting that mTOR (show FRAP1 Antibodies) inhibitors might be effective in control of FLCN-deficient RCC (show XRCC1 Antibodies).

  4. we show that glycogen (show GYS1 Antibodies) accumulates in kidneys from mice lacking FLCN and in renal tumors from a BHD patient

  5. Case Report: FLCN deletion mutation in members of Indian Birt-Hogg-Dube syndrome family.

  6. This report documents the first identification of founder mutations in FLCN, as well as expands mutation spectrum of the gene

  7. FLCN-related renal cell carcinomas showed overexpression of GPNMB and underexpression of FLCN, whereas sporadic tumors showed inverted patterns.

  8. The FLCN-GABARAP (show GABARAP Antibodies) association is modulated by the presence of either folliculin-interacting protein (FNIP)-1 (show FNIP1 Antibodies) or FNIP2 (show FNIP2 Antibodies) and further regulated by ULK1 (show ULK1 Antibodies).

  9. Two predominant genes, ephrin type A receptor 6 (EPHA6 (show Epha6 Antibodies)) and folliculin (FLCN), with mutations exclusive to African American CRCs, are by genetic and biological criteria highly likely African American CRC (show CALR Antibodies) driver genes.

  10. Findings suggest that folliculin deficient renal cell carcinoma (show MOK Antibodies) cells are highly sensitive to irradiation due to increased autophagic cell death, unlike other types of renal cell carcinoma (show MOK Antibodies).

FLCN Antigen Profile

Protein Summary

This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Gene names and symbols associated with anti-Folliculin (FLCN) Antibodies

  • folliculin (FLCN) antibody
  • folliculin (flcn) antibody
  • folliculin (Flcn) antibody
  • AU014660 antibody
  • B430214A04Rik antibody
  • BHD antibody
  • FLCL antibody
  • flcn antibody
  • wu:fe38g11 antibody
  • zgc:136982 antibody

Protein level used designations for anti-Folliculin (FLCN) Antibodies

folliculin , folliculin-like , birt-Hogg-Dube syndrome protein homolog , BHD skin lesion fibrofolliculoma protein , birt-Hogg-Dube syndrome protein

GENE ID SPECIES
454472 Pan troglodytes
698082 Macaca mulatta
496819 Xenopus (Silurana) tropicalis
678628 Danio rerio
100158392 Xenopus laevis
100395467 Callithrix jacchus
100431335 Pongo abelii
100470222 Ailuropoda melanoleuca
216805 Mus musculus
303185 Rattus norvegicus
201163 Homo sapiens
416503 Gallus gallus
479529 Canis lupus familiaris
526652 Bos taurus
Selected quality suppliers for anti-FLCN (FLCN) Antibodies
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