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Folliculogenesis Specific Basic Helix-Loop-Helix Proteins (FIGLA)

FIGLA encodes a protein that functions in postnatal oocyte-specific gene expression. Additionally we are shipping FIGLA Antibodies (24) and FIGLA Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FIGLA 344018 Q6QHK4
FIGLA 26910 O55208
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Top FIGLA Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

FIGLA Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Folliculogenesis Specific Basic Helix-Loop-Helix (FIGLA) Interaction Partners

Human Folliculogenesis Specific Basic Helix-Loop-Helix (FIGLA) interaction partners

  1. study identified an association between FIGLA gene variants and the occurrence of premature ovarian failure(POF (show POF1B Proteins)) in the Indian population; findings suggest that the c.427G->C and c.557C->T alleles lead to an increased risk of POF (show POF1B Proteins) in Indian women

  2. These results suggest that FIGLA is involved in continued oocyte survival as primordial follicles form in the human as in the rodent ovary.

  3. the p.140 delN mutation disrupted FIGLA binding to the TCF3 (show TCF3 Proteins) helix-loop-helix (HLH) domain. Our findings show that a subset of Chinese women with sporadic, premature ovarian failure harbor mutations in FIGLA.

Mouse (Murine) Folliculogenesis Specific Basic Helix-Loop-Helix (FIGLA) interaction partners

  1. GFP positive cells showed the expression of germ cell markers Vasa (show DDX4 Proteins), meiotic specific gene Stra8, Scp3 (show SYCP3 Proteins), oocyte markers Gdf9 (show GDF9 Proteins), Zp3 (show ZP3 Proteins) and Figla, indicating that this method could be used for the purification and selection of female germ cells

  2. Data suggest that a dynamic DNA CpG methylation in Sohlh2 (show SOHLH2 Proteins) and Figlalpha promoters, but not in the intron and exon sequences, is linked to regulation of gene expression, even though CpG islands are also present in their introns or exons.

  3. physiological expression of Figla plays a critical dual role in activation of oocyte-associated genes and repression of sperm-associated genes during normal postnatal oogenesis

  4. FIGLA is a central regulator of oocyte-specific genes that play roles in folliculogenesis, fertilization and early development.

FIGLA Protein Profile

Protein Summary

This gene encodes a protein that functions in postnatal oocyte-specific gene expression. The protein is a basic helix-loop-helix transcription factor that regulates multiple oocyte-specific genes, including genes involved in folliculogenesis and those that encode the zona pellucida. Mutations in this gene cause premature ovarian failure type 6.

Gene names and symbols associated with FIGLA

  • folliculogenesis specific basic helix-loop-helix (FIGLA)
  • folliculogenesis specific basic helix-loop-helix (Figla)
  • bHLHc8 protein
  • FIGALPHA protein
  • POF6 protein

Protein level used designations for FIGLA

class C basic helix-loop-helix protein 8 , factor in the germline alpha , folliculogenesis-specific basic helix-loop-helix protein , transcription factor FIGa , FIG alpha , FIGalpha

GENE ID SPECIES
344018 Homo sapiens
26910 Mus musculus
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