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FSTL1 encodes a protein with similarity to follistatin, an activin-binding protein. Additionally we are shipping FSTL1 Antibodies (97) and FSTL1 Kits (39) and many more products for this protein.
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Human FSTL1 Protein expressed in HEK-293 Cells - ABIN2181121
Ehara, Sakurai, Tsuchiya, Nakano, Tanaka, Yamaguchi, Tokunaga: Follistatin-related protein gene (FRP) is expressed in the synovial tissues of rheumatoid arthritis, but its polymorphisms are not associated with genetic susceptibility. in Clinical and experimental rheumatology 2005
Show all 2 references for ABIN2181121
FSTL1 plays a critical role in immune regulation, enhancing the antigen presentation ability of dendritic cells by up-regulating NF-kappab (show NFKB1 Proteins) expression and down-regulating JNK (show MAPK8 Proteins) expression.
the knockdown of FSTL1 induces apoptosis through a mitotic arrest and caspase (show CASP3 Proteins)-dependent cell death. FSTL1 plays the important roles in cellular proliferation and apoptosis in lung cancer cells, and thus can be a new target for lung cancer treatment.
Children with chronic heart failure group had a significantly higher serum level of FSTL1 than the control group.
provide mechanistic insight into the regulation of erythropoiesis by FSTL1 signaling and lay a foundation for exploring FSTL1 signaling as a therapeutic target for anemia
FSTL1 is elevated in patients with osteoarthritis and involved in the progression of synovial inflammation.
administration of Fstl1 induced airway remodeling and increased OSM (show OSM Proteins), whereas administration of an anti-OSM (show OSM Proteins) Ab blocked the effect of Fstl1 on inducing airway remodeling, eosinophilic airway inflammation
data suggest that the loss of epicardial FSTL1 is a maladaptive response to injury, and that its restoration would be an effective way to reverse myocardial death and remodelling following myocardial infarction in humans
Fstl1 is induced in response to lung injury and promotes the accumulation of myofibroblasts and subsequent fibrosis. These data suggest that Fstl1 may serve as a novel therapeutic target for treatment of progressive lung fibrosis.
FSTL1 is elevated in various inflammatory conditions and decreased during the course of treatment. FSTL1 may therefore be a valuable biomarker for such diseases.
FSTL1 is a potential mediator of inflammation and insulin (show INS Proteins) resistance in obesity.
a new role for FSTL1 in the development of radial glial scaffolds and the neuronal migration of upper-layer projection neurons, is reported.
epicardial cells contain a potent cardiogenic activity identified as follistatin-like 1 (Fstl1)
FSTL1 is a potent regulator of chondrocyte proliferation, differentiation and expression of extracellular matrix molecules.
muscle-derived Fstl1 attenuates neointimal formation in response to arterial injury by suppressing smooth muscle cell proliferation through an AMPK (show PRKAA1 Proteins)-dependent mechanism
functions in cardiorenal communication; lack of Fstl1 production by myocytes promotes glomerular and tubulointerstitial damage in the kidney
This study is the first to describe a role for FSTL-1 in the development of Lyme arthritis and anti-Borrelia response.
This gene encodes a protein with similarity to follistatin, an activin-binding protein. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. This gene product is thought to be an autoantigen associated with rheumatoid arthritis.
, Follistatin-related protein 1
, follistatin-like protein 1
, follistatin-related protein 1
, TGF-beta-inducible protein TSC-36