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Follistatin-like 3 is a secreted glycoprotein of the follistatin-module-protein family. Additionally we are shipping FSTL3 Kits (20) and FSTL3 Proteins (8) and many more products for this protein.
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Human Polyclonal FSTL3 Primary Antibody for EIA, IHC (p) - ABIN952356
Miron, Lambert, Marcil, Cowans, Stamatopoulou, Spencer: Maternal plasma levels of follistatin-related gene protein in the first trimester of pregnancies with Down syndrome. in Prenatal diagnosis 2010
Show all 3 references for ABIN952356
FSTL3 KO lead to increased activin (show Actbeta Antibodies) signaling, enhancing alpha- to beta-cell transdifferentiation in mouse islets.
FSTL3 is a critical mediator of exercise-dependent bone formation
Data indicate that deletion of activin (show Actbeta Antibodies) antagonists follistatin-like-3 (FSTL3) results in hepatic steatosis
Suggest FSTL3 has a role in paracrine communication between cardiomyocytes and fibroblasts.
crucial roles for FSTL3 in limiting testis organ size and promoting age-related testicular regression
These findings link FSTL3 and TGFbeta (show TGFB1 Antibodies) ligand signaling and a novel subset of the synexpression group of genes to organ/tissue-specific regulatory pathways.
These results demonstrate that body composition and glucose homeostasis are differentially regulated by FST (show FST Antibodies) and FSTL3 and that their combined loss is associated with increased fat mass and insulin (show INS Antibodies) resistance despite elevated insulin (show INS Antibodies) production.
Fstl3 as a stress-induced regulator of hypertrophy that controls myocyte size via regulation of Smad (show SMAD1 Antibodies) signaling.
regulation and expression patterns of follistatin (show FST Antibodies) and FLRG differ; FLRG is distributed in spermatogenic cells of the testis, renal tubules, epithelial cells of the lung, and myocardium
review with emphasis on authors' works on paracrine and autocrine regulation in activities of Fst (show FST Antibodies) and Fstl3, regulation of gonadal development, and structural elements necessary for biological activities
Elevated FSTL-3 concentrations were attributable to preeclampsia and were associated with increased likelihood of later developing preeclampsia, suggesting further study as a biomarker prior to clinically evident disease.
The elevation of Follistatin-like-3 was demonstrated in late second trimester of pregnancy destined to developing preeclampsia, suggesting its causal role in the pathogenesis and prediction of preeclampsia.
Resistance exercise resulted in a significant downregulation of MSTN (show MSTN Antibodies) and FBXO32 (show FBXO32 Antibodies) mRNA expression and a significant upregulation in FSTL3 and SMURF1 (show SMURF1 Antibodies) mRNA expression, and carbohydrate and protein feeding have little influence on the these markers expression.
Data suggest that serum levels of FSTL3 are higher in pre-eclampsia than in controls; placental expression of FSTL3 is also increased in pre-eclampsia compared with controls; no differences were observed between mild and severe pre-eclampsia.
After eccentric exercise, postmenopausal women not using hormone therapy (HT) expressed higher levels of follistatin-like protein 3 while postmenopausal women using HT showed a significant increased expression over controls.
Maternal and placental FSTL3 concentrations were reduced in GDM women compared with normally pregnant women, suggesting FSTL3 may play an important role in the pathogenesis of gestational diabetes
Structure of myostatin.follistatin-like 3: N-terminal domains of follistatin (show FST Antibodies)-type molecules exhibit alternate modes of binding.
GDF9 (show GDF9 Antibodies) decreases basal and activin A (show INHBA Antibodies)-induced FST (show FST Antibodies) and FSTL3 expression, and this explains, in part, its enhancing effects on activin A (show INHBA Antibodies)-induced inhibin beta(B)-subunit (show INHBB Antibodies) mRNA expression and inhibin B production in hGL (show LLGL2 Antibodies) cells
Follistatin-like 3 is a secreted glycoprotein of the follistatin-module-protein family. It may have a role in leukemogenesis.
follistatin-like protein 3
, follistatin-related gene protein
, follistatin-related protein 3