anti-Forkhead Box C2 (MFH-1, Mesenchyme Forkhead 1) (FOXC2) Antibodies

FOXC2 belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. Additionally we are shipping FOXC2 Kits (25) and FOXC2 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FOXC2 14234 Q61850
FOXC2 171356  
FOXC2 2303 Q99958
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Top anti-FOXC2 Antibodies at antibodies-online.com

Showing 10 out of 127 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-FOXC2 Antibody Titration: 1.25ug/ml ELISA Titer: 1:1562500 Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$229.00
Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-Foxc2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Mouse Uterus WB Suggested Anti-Foxc2 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: Mouse Uterus 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB FOXC2 Antibody (Center S174) (ABIN651936) western blot analysis in A2058 cell line lysates (15 µg/lane). This demonstrates the FOXC2 antibody detected the FOXC2 protein (arrow). FOXC2 Antibody (Center S174) (ABIN651936) immunohistochemistry analysis in formalin fixed and paraffin embedded human cervix carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, WB FOXC2 Antibody (Center P198) (ABIN655526) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated ELISA, ICC, IF, IHC, IHC (fro), IHC (p), WB Western Blot: FOX C2 Antibody [ABIN249942] - ABIN249942 staining (1ug/ml) of Human Breast Cancer lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Western Blot: FoxC2 Antibody [ABIN249942] - HEK293 lysate (10ug protein in RIPA buffer) over expressing Human FOXC2 with DYKDDDDK tag probed with FoxC2 (0.1ug/ml) in Lane A and probed with anti- DYKDDDDK Tag (1/1000) in lane C. Mock-transfected HEK293 probed with FoxC2 (1mg/ml) in Lane B. Prima 0.1 mg Log in to see 7 to 9 Days
$447.56
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN185029 staining (1µg/ml) of Human Breast Cancer lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. HEK293 lysate (10 µg protein in RIPA buffer) over expressing Human FOXC2 with DYKDDDDK tag probed with ABIN185029 (0.1 µg/mL) in Lane A and probed with anti- DYKDDDDK Tag (1/1000) in lane C. Mock-transfected HEK293 probed with ABIN185029 (1mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$326.89
Details
Human Rabbit Un-conjugated EIA, FACS, WB Flow cytometric analysis of HL-60 cells using FOXC2 Antibody  (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Western blot analysis of FOXC2 Antibody  in WiDr,HL-60,ZR-75-1,MDA-MB231 cell line lysates (35ug/lane). This demonstrates the FOXC2 antibody detected the FOXC2 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Goat Un-conjugated IHC (p), WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details

FOXC2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,
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Rat (Rattus)
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Top referenced anti-FOXC2 Antibodies

  1. Human Polyclonal FOXC2 Primary Antibody for ELISA, ICC - ABIN249942 : Zarbalis, Siegenthaler, Choe, May, Peterson, Pleasure: Cortical dysplasia and skull defects in mice with a Foxc1 allele reveal the role of meningeal differentiation in regulating cortical development. in Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal FOXC2 Primary Antibody for IF, IHC (p) - ABIN560913 : Nishida, Mimori, Yokobori, Sudo, Tanaka, Shibata, Ishii, Doki, Mori: FOXC2 is a novel prognostic factor in human esophageal squamous cell carcinoma. in Annals of surgical oncology 2011 (PubMed)
    Show all 3 Pubmed References

  3. Human Monoclonal FOXC2 Primary Antibody for ELISA, WB - ABIN1724771 : Jiang, Pang, Wang, Shen, Chen, Xi: Prognostic role of Twist, Slug, and Foxc2 expression in stage I non-small-cell lung cancer after curative resection. in Clinical lung cancer 2012 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal FOXC2 Primary Antibody for ELISA, WB - ABIN1724772 : Watanabe, Kobunai, Yamamoto, Matsuda, Ishihara, Nozawa, Iinuma, Kanazawa, Tanaka, Konishi, Ikeuchi, Eshima, Muto, Nagawa: Gene expression of mesenchyme forkhead 1 (FOXC2) significantly correlates with the degree of lymph node metastasis in colorectal cancer. in International surgery 2012 (PubMed)
    Show all 2 Pubmed References

  5. Cow (Bovine) Polyclonal FOXC2 Primary Antibody for WB - ABIN610743 : Henis-Korenblit, Strumpf, Goldstaub, Kimchi: A novel form of DAP5 protein accumulates in apoptotic cells as a result of caspase cleavage and internal ribosome entry site-mediated translation. in Molecular and cellular biology 2000 (PubMed)
    Show all 2 Pubmed References

More Antibodies against FOXC2 Interaction Partners

Mouse (Murine) Forkhead Box C2 (MFH-1, Mesenchyme Forkhead 1) (FOXC2) interaction partners

  1. FOXC1 (show FOXC1 Antibodies) and FOXC2 are essential regulators of lymphangiogenesis and may have roles in lymphatic-associated diseases

  2. Compound, NC-specific Foxc1 (show FOXC1 Antibodies); Foxc2 homozygous mutant mice have more severe defects in structures of the ocular surface, such as the cornea and eyelids, accompanied by significant declines in the expression of another key developmental factor, Pitx2 (show PITX2 Antibodies), and its downstream effector Dkk2 (show DKK2 Antibodies), which antagonizes canonical Wnt (show WNT2 Antibodies) signaling.

  3. Foxc1 (show FOXC1 Antibodies) and Foxc2 maintain glomerular podocyte integrity by regulating the gene expression. Foxc2 plays a more critical role than Foxc1 (show FOXC1 Antibodies).

  4. Foxc1 (show FOXC1 Antibodies) and Foxc2 have a role in kidney and axial skeleton development.

  5. Our results are consistent with previous reports of Foxc2 expression during early embryogenesis and the Foxc2(CreERT2) mouse provides a tool to investigate spatiotemporal roles of Foxc2 and contributions of Foxc2(+) expressing cells during mouse embryogenesis.

  6. Conditional knockout of Foxc2 gene in kidney has been generated using conditional alleles of single-exon gene by double-selection system.

  7. Data show that segregation of Foxc2 and NFATc1 (show NFATC1 Antibodies) transcription factor is closely associated with the highly polarized expression of connexins Cx37 (show GJA4 Antibodies), Cx43 (show GJA1 Antibodies), and Cx47 (show GJC2 Antibodies).

  8. deletion of Foxc1 (show FOXC1 Antibodies) and Foxc2 specifically in Pax3 (show PAX3 Antibodies)-positive cells affects cell fate choices in the dermomyotome of somites at forelimb level, promoting the myogenic cell fate at the expense of endothelial cells that migrate to the limb

  9. Foxc2 in pharyngeal arch mesenchyme is important for aortic arch artery remodelling and ventricular septum formation

  10. Foxc2 enhances proliferation of preadipocytes and inhibits apoptosis of preadipocytes by activating the Akt (show AKT1 Antibodies)/mTORC1 and ERK (show EPHB2 Antibodies)/mTORC1 signaling pathways

Human Forkhead Box C2 (MFH-1, Mesenchyme Forkhead 1) (FOXC2) interaction partners

  1. This is the first report of a FOXC2 mutation in hereditary distichiasis in the Chinese population. The findings expand the FOXC2 mutation spectrum and contribute to the understanding of the genotype-phenotype correlation of this disease.

  2. FOXC2 promoted the glycolysis in progression of nasopharyngeal carcinoma by activating YAP (show YAP1 Antibodies) signaling

  3. FOXC1 (show FOXC1 Antibodies) and FOXC2 are essential regulators of lymphangiogenesis and may have roles in lymphatic-associated diseases

  4. Authors concluded that the lncRNA FOXC2-AS1 (show PTGDR Antibodies) may promote doxorubicin resistance in OS by increasing the expression of transcription factor FOXC2, further facilitating ABCB1 (show ABCB1 Antibodies) expression.

  5. we demonstrate that FOXC2 is an important determinant of PCa (show FLVCR1 Antibodies) stem-cell attributes, dictating the biochemical shift to ADT- and chemo-resistance

  6. our data demonstrate that FOXC2 regulates EMT (show ITK Antibodies), stem cell traits, ZEB1 (show ZEB1 Antibodies) expression and metastasis in a p38 (show CRK Antibodies)-dependent manner, and attest to the potential utility of p38 (show CRK Antibodies) inhibitors as antimetastatic agents.

  7. Moreover, PLK1 (show PLK1 Antibodies) activity is important for FOXC2 protein stability, since PLK1 (show PLK1 Antibodies) inhibition reduces FOXC2 protein levels.

  8. Data suggest that forkhead box protein C2 (FOXC2) could be a potential therapeutic target for overcoming cisplatin (CDDP) resistance in ovarian cancer.

  9. High expression of FOXC2 is associated with pancreatic ductal adenocarcinoma.

  10. FOXC2 promotes epithelial-mesenchymal transition, migration and invasion in cisplatin-resistant human ovarian cancer cells.

FOXC2 Antigen Profile

Protein Summary

This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined\; however, it may play a role in the development of mesenchymal tissues.

Gene names and symbols associated with FOXC2

  • forkhead box C2 (MFH-1, mesenchyme forkhead 1) (FOXC2) antibody
  • forkhead box C2 (FOXC2) antibody
  • forkhead box C2 (Foxc2) antibody
  • Fkh14 antibody
  • FKHL14 antibody
  • FOXC2 antibody
  • Hfhbf3 antibody
  • LD antibody
  • MFH-1 antibody
  • MFH1 antibody

Protein level used designations for FOXC2

forkhead box C2 (MFH-1, mesenchyme forkhead 1) , forkhead box C2 , forkhead box protein C2 , forkhead box protein C2-like , BF-3 , brain factor 3 , forkhead homolog 14 , forkhead-related protein FKHL14 , mesenchyme fork head protein 1 , transcription factor FKH-14 , HFH-BF-3 , forkhead box C2 (MFH-1 mesenchyme forkhead 1) , winged helix transcriptional factor MFH-1 , MFH-1,mesenchyme forkhead 1 , forkhead, Drosophila, homolog-like 14

GENE ID SPECIES
468058 Pan troglodytes
694852 Macaca mulatta
100036555 Equus caballus
100407050 Callithrix jacchus
14234 Mus musculus
171356 Rattus norvegicus
396039 Gallus gallus
2303 Homo sapiens
489671 Canis lupus familiaris
507300 Bos taurus
101103500 Ovis aries
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