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anti-Forkhead Box C2 (MFH-1, Mesenchyme Forkhead 1) (FOXC2) Antibodies

FOXC2 belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. Additionally we are shipping FOXC2 Kits (23) and FOXC2 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FOXC2 14234 Q61850
FOXC2 171356  
FOXC2 2303 Q99958
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Top anti-FOXC2 Antibodies at antibodies-online.com

Showing 10 out of 110 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$229.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated FACS, WB FOXC2 Antibody (Center P198) (ABIN655526) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB FOXC2 Antibody (Center S174) (ABIN651936) western blot analysis in A2058 cell line lysates (15 µg/lane). This demonstrates the FOXC2 antibody detected the FOXC2 protein (arrow). FOXC2 Antibody (Center S174) (ABIN651936) immunohistochemistry analysis in formalin fixed and paraffin embedded human cervix carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Goat Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN185029 staining (1µg/ml) of Human Breast Cancer lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. HEK293 lysate (10 µg protein in RIPA buffer) over expressing Human FOXC2 with DYKDDDDK tag probed with ABIN185029 (0.1 µg/mL) in Lane A and probed with anti- DYKDDDDK Tag (1/1000) in lane C. Mock-transfected HEK293 probed with ABIN185029 (1mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$326.89
Details
Human Rabbit Un-conjugated EIA, FACS, WB Flow cytometric analysis of HL-60 cells using FOXC2 Antibody  (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Western blot analysis of FOXC2 Antibody  in WiDr,HL-60,ZR-75-1,MDA-MB231 cell line lysates (35ug/lane). This demonstrates the FOXC2 antibody detected the FOXC2 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated ELISA, WB 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Foxc2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Mouse Uterus WB Suggested Anti-Foxc2  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Mouse Uterus 100 μL Log in to see 2 to 3 Days
$289.00
Details

FOXC2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,
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Rat (Rattus)
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Human , ,
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Top referenced anti-FOXC2 Antibodies

  1. Human Polyclonal FOXC2 Primary Antibody for EIA, FACS - ABIN952363 : Sánchez-Carpintero, Dominguez, Núñez, Patiño-García: Spinal extradural arachnoid cysts in lymphedema-distichiasis syndrome. in Genetics in medicine : official journal of the American College of Medical Genetics 2010 (PubMed)
    Show all 3 references for ABIN952363

  2. Human Monoclonal FOXC2 Primary Antibody for ELISA, WB - ABIN1724772 : Jiang, Pang, Wang, Shen, Chen, Xi: Prognostic role of Twist, Slug, and Foxc2 expression in stage I non-small-cell lung cancer after curative resection. in Clinical lung cancer 2012 (PubMed)
    Show all 2 references for ABIN1724772

  3. Cow (Bovine) Polyclonal FOXC2 Primary Antibody for WB - ABIN610743 : Henis-Korenblit, Strumpf, Goldstaub, Kimchi: A novel form of DAP5 protein accumulates in apoptotic cells as a result of caspase cleavage and internal ribosome entry site-mediated translation. in Molecular and cellular biology 2000 (PubMed)
    Show all 2 references for ABIN610743

  4. Human Polyclonal FOXC2 Primary Antibody for IHC, ELISA - ABIN185029 : Brice, Mansour, Bell, Collin, Child, Brady, Sarfarazi, Burnand, Jeffery, Mortimer, Murday: Analysis of the phenotypic abnormalities in lymphoedema-distichiasis syndrome in 74 patients with FOXC2 mutations or linkage to 16q24. in Journal of medical genetics 2002 (PubMed)

  5. Cow (Bovine) Polyclonal FOXC2 Primary Antibody for IHC (p), WB - ABIN374337 : Hayashi, Sano, Seo, Kume: The Foxc2 transcription factor regulates angiogenesis via induction of integrin beta3 expression. in The Journal of biological chemistry 2008 (PubMed)

  6. Cow (Bovine) Polyclonal FOXC2 Primary Antibody for WB - ABIN2779557 : Yanagisawa, Hingstrup Larsen, Andersen, Drivsholm, Cederberg, Westergren, Borch-Johnsen, Pedersen, Enerbäck, Hansen: The FOXC2 -512C>T variant is associated with hypertriglyceridaemia and increased serum C-peptide in Danish Caucasian glucose-tolerant subjects. in Diabetologia 2003 (PubMed)

  7. Cow (Bovine) Polyclonal FOXC2 Primary Antibody for WB - ABIN2777422 : Fujita, Kang, Eren, Gleaves, Vaughan, Kume: Foxc2 is a common mediator of insulin and transforming growth factor beta signaling to regulate plasminogen activator inhibitor type I gene expression. in Circulation research 2006 (PubMed)

  8. Human Polyclonal FOXC2 Primary Antibody for FACS, WB - ABIN655526 : Jugessur, Shi, Gjessing, Lie, Wilcox, Weinberg, Christensen, Boyles, Daack-Hirsch, Nguyen, Christiansen, Lidral, Murray: Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. in PLoS ONE 2010 (PubMed)

  9. Human Polyclonal FOXC2 Primary Antibody for FACS, IHC (p) - ABIN651936 : Miura, Iida, Kakinuma, Yang, Sugiyama: Isolation of the mouse (MFH-1) and human (FKHL 14) mesenchyme fork head-1 genes reveals conservation of their gene and protein structures. in Genomics 1997 (PubMed)

More Antibodies against FOXC2 Interaction Partners

Mouse (Murine) Forkhead Box C2 (MFH-1, Mesenchyme Forkhead 1) (FOXC2) interaction partners

  1. Compound, NC-specific Foxc1 (show FOXC1 Antibodies); Foxc2 homozygous mutant mice have more severe defects in structures of the ocular surface, such as the cornea and eyelids, accompanied by significant declines in the expression of another key developmental factor, Pitx2 (show PITX2 Antibodies), and its downstream effector Dkk2 (show DKK2 Antibodies), which antagonizes canonical Wnt (show WNT2 Antibodies) signaling.

  2. Foxc1 (show FOXC1 Antibodies) and Foxc2 maintain glomerular podocyte integrity by regulating the gene expression. Foxc2 plays a more critical role than Foxc1 (show FOXC1 Antibodies).

  3. Foxc1 (show FOXC1 Antibodies) and Foxc2 have a role in kidney and axial skeleton development.

  4. Our results are consistent with previous reports of Foxc2 expression during early embryogenesis and the Foxc2(CreERT2) mouse provides a tool to investigate spatiotemporal roles of Foxc2 and contributions of Foxc2(+) expressing cells during mouse embryogenesis.

  5. Conditional knockout of Foxc2 gene in kidney has been generated using conditional alleles of single-exon gene by double-selection system.

  6. Data show that segregation of Foxc2 and NFATc1 (show NFATC1 Antibodies) transcription factor is closely associated with the highly polarized expression of connexins Cx37 (show GJA4 Antibodies), Cx43 (show GJA1 Antibodies), and Cx47 (show GJC2 Antibodies).

  7. deletion of Foxc1 (show FOXC1 Antibodies) and Foxc2 specifically in Pax3 (show PAX3 Antibodies)-positive cells affects cell fate choices in the dermomyotome of somites at forelimb level, promoting the myogenic cell fate at the expense of endothelial cells that migrate to the limb

  8. Foxc2 in pharyngeal arch mesenchyme is important for aortic arch artery remodelling and ventricular septum formation

  9. Foxc2 enhances proliferation of preadipocytes and inhibits apoptosis of preadipocytes by activating the Akt (show AKT1 Antibodies)/mTORC1 and ERK (show EPHB2 Antibodies)/mTORC1 signaling pathways

  10. In murine models, inducible deletion of Foxc2 within the lymphatic vasculature led to cell-cell junction defects, regression of valves, and focal vascular lumen collapse, which triggered g (show TAZ Antibodies)eneralized lymphatic vascular dysfunction and lethality.

Human Forkhead Box C2 (MFH-1, Mesenchyme Forkhead 1) (FOXC2) interaction partners

  1. Moreover, PLK1 (show PLK1 Antibodies) activity is important for FOXC2 protein stability, since PLK1 (show PLK1 Antibodies) inhibition reduces FOXC2 protein levels.

  2. Data suggest that forkhead box protein C2 (FOXC2) could be a potential therapeutic target for overcoming cisplatin (CDDP) resistance in ovarian cancer.

  3. High expression of FOXC2 is associated with pancreatic ductal adenocarcinoma.

  4. FOXC2 promotes epithelial-mesenchymal transition, migration and invasion in cisplatin-resistant human ovarian cancer cells.

  5. Evaluation of FoxC2 expression, alone or in combination with E-cadherin (show CDH1 Antibodies) expression, may help to stratify non-small cell lung cancer patients for risk of disease progression, pointing to this EMT (show ITK Antibodies) regulator as a potential prognostic marker

  6. Data indicate the role for altered forkhead box C2 (FoxC2)-Delta-like (show DLK1 Antibodies) ligand 4 (Dll4 (show DLL4 Antibodies))signaling in structural alterations of saphenous veins in patients with varicose veins.

  7. FOXC2 gene is associated with the glycolipid metabolic abnormality in T2DM patients.

  8. Adenovirus-mediated FoxC2 expression enhances BMP7 (show BMP7 Antibodies)-facilitated anabolism in nucleus pulposus cells of the intervertebral discs.

  9. The data indicate that the expression of FOXC2 in podocytes needs to be tightly regulated, and that its overexpression induces a chain of cellular events leading to podocyte dysfunction.

  10. Peri (show PLIN1 Antibodies)-tumoral lymphatics were associated with increased lymphatic metastasis. FOXC2 may be associated with the genesis of endometrial carcinoma and lymphangiogensis in endometrial adenocarcinoma in intra- and peri (show PLIN1 Antibodies)-tumoral lymphatics.

FOXC2 Antigen Profile

Protein Summary

This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined\; however, it may play a role in the development of mesenchymal tissues.

Gene names and symbols associated with FOXC2

  • forkhead box C2 (MFH-1, mesenchyme forkhead 1) (FOXC2) antibody
  • forkhead box C2 (FOXC2) antibody
  • forkhead box C2 (Foxc2) antibody
  • Fkh14 antibody
  • FKHL14 antibody
  • FOXC2 antibody
  • Hfhbf3 antibody
  • LD antibody
  • MFH-1 antibody
  • MFH1 antibody

Protein level used designations for FOXC2

forkhead box C2 (MFH-1, mesenchyme forkhead 1) , forkhead box C2 , forkhead box protein C2 , forkhead box protein C2-like , BF-3 , brain factor 3 , forkhead homolog 14 , forkhead-related protein FKHL14 , mesenchyme fork head protein 1 , transcription factor FKH-14 , HFH-BF-3 , forkhead box C2 (MFH-1 mesenchyme forkhead 1) , winged helix transcriptional factor MFH-1 , MFH-1,mesenchyme forkhead 1 , forkhead, Drosophila, homolog-like 14

GENE ID SPECIES
468058 Pan troglodytes
694852 Macaca mulatta
100036555 Equus caballus
100407050 Callithrix jacchus
14234 Mus musculus
171356 Rattus norvegicus
396039 Gallus gallus
2303 Homo sapiens
489671 Canis lupus familiaris
507300 Bos taurus
101103500 Ovis aries
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