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Forkhead Box E1 (Thyroid Transcription Factor 2) Proteins (FOXE1)

This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. Additionally we are shipping FOXE1 Antibodies (57) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FOXE1 110805 Q8R2I0
FOXE1 2304 O00358
Rat FOXE1 FOXE1 192274  
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Top FOXE1 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 Days
$5,442.50
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Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 Days
$5,442.50
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Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$3,041.50
Details

FOXE1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human

More Proteins for Forkhead Box E1 (Thyroid Transcription Factor 2) (FOXE1) Interaction Partners

Mouse (Murine) Forkhead Box E1 (Thyroid Transcription Factor 2) (FOXE1) interaction partners

  1. These results indicate that Foxe1 overexpression is not directly involved in the development of thyroid cancer and that proper Foxe1 dosage is essential for achieving normal structure and function of the thyroid.

  2. Foxe1 mRNA expression was suppressed in HR-overexpressing skin, as well as in HR-expressing keratinocytes.

  3. MSX1 (show MSX1 Proteins) and TGF-beta3 (show TGFB3 Proteins) are direct targets of FOXE1.

  4. Data report a detailed expression pattern of thyroid transcription factor-2 protein during mouse embryogenesis.

  5. Foxe1 is required for hair follicle morphogenesis.

Human Forkhead Box E1 (Thyroid Transcription Factor 2) (FOXE1) interaction partners

  1. In the analysis of all OFCs combined, SNPs near FOXE1 reached genome-wide significance

  2. We confirmed associations with papillary thyroid cancer and SNPs in FOXE1/HEMGN, SERPINA5 (show SERPINA5 Proteins) (rs2069974), FTO (show FTO Proteins) (rs8047395), EVPL (rs2071194), TICAM1 (show TICAM1 Proteins) (rs8120) and SCARB1 (show SCARB1 Proteins) (rs11057820) genes. We found associations with SNPs in FOXE1, SERPINA5 (show SERPINA5 Proteins), FTO (show FTO Proteins), TICAM1 (show TICAM1 Proteins) and HSPA6 (show HSPA6 Proteins) and and follicular thyroid cancer

  3. FOXE1 was the only gene which was over-expressed in six out of eight lung cancer cell lines and human cancer tissue specimens and is an important regulator by targeting autophagy and Matrix Metalloproteinases pathways in lung cancer development.

  4. Taken together, this study showed that rs7043516 may be considered as a potentially susceptible marker of cleft lip only among Chinese Han populations.

  5. this study shows that FOXE1 polymorphism is strongly associated with non-syndromic cleft lip and palate in populations in northeast China

  6. High Levels of mRNA of both FOXE1 are associated with benign than in malignant thyroid lesions.

  7. Our findings suggest that FOXE1 variations generate a higher risk for poor histopathological features of papillary thyroid carcinoma

  8. analysis of novel somatic mutations of FOXE1 in papillary thyroid cancer

  9. Causal mutations for orofacial clefting and thyroid diseases occur within cis (show CISH Proteins)-regulatory elements at the human FOXE1 locus.

  10. In pancreatic cancer cells, AF6 is expressed at reduced levels, causing Dvl2 (show DVL2 Proteins) to be upregulated and available to bind and enhance FOXE1-induced trans-activation of Snail (show SNAI1 Proteins), which promotes proliferation and metastasis.

Xenopus laevis Forkhead Box E1 (Thyroid Transcription Factor 2) (FOXE1) interaction partners

  1. Xenopus FoxE1, a gene that is primarily expressed in the developing pituitary and thyroid

FOXE1 Protein Profile

Protein Summary

This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. This gene functions as a thyroid transcription factor which likely plays a crucial role in thyroid morphogenesis. Mutations in this gene are associated with congenital hypothyroidism and cleft palate with thyroid dysgenesis. The map localization of this gene suggests it may also be a candidate gene for squamous cell epithelioma and hereditary sensory neuropathy type I.

Gene names and symbols associated with FOXE1

  • foxE protein (foxE)
  • forkhead box E1 (thyroid transcription factor 2) (foxe1)
  • forkhead box E1 (foxE1)
  • forkhead box E1 (Foxe1)
  • forkhead box E1 (thyroid transcription factor 2) (FOXE1)
  • forkhead box E1 (thyroid transcription factor 2) (Foxe1)
  • transcription termination factor, RNA polymerase II (TTF2)
  • Ci-FoxE protein
  • FKHL15 protein
  • foxE protein
  • foxE1 protein
  • FOXE2 protein
  • FoxE5 protein
  • HFKH4 protein
  • HFKL5 protein
  • TITF2 protein
  • Ttf-2 protein
  • TTF2 protein

Protein level used designations for FOXE1

forkhead box E1 (thyroid transcription factor 2) , forkhead box E1 , forkhead box E protein , thyroid transcription factor 2 , TTF-2 , forkhead box protein E1 , HNF-3/fork head-like protein 5 , forkhead box E2 , forkhead box protein E2 , forkhead, drosophila, homolog-like 15 , forkhead-related protein FKHL15

GENE ID SPECIES
445746 Ciona intestinalis
567676 Danio rerio
100038190 Xenopus (Silurana) tropicalis
100303469 Saccoglossus kowalevskii
110805 Mus musculus
2304 Homo sapiens
192274 Rattus norvegicus
768789 Gallus gallus
100683977 Canis lupus familiaris
616734 Bos taurus
496399 Xenopus laevis
418376 Gallus gallus
100684320 Canis lupus familiaris
100156166 Sus scrofa
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