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Forkhead Box H1 Proteins (FOXH1)

FOXH1 encodes a human homolog of Xenopus forkhead activin signal transducer-1. Additionally we are shipping FOXH1 Antibodies (62) and FOXH1 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FOXH1 8928 O75593
FOXH1 14106 O88621
Rat FOXH1 FOXH1 300054  
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Top FOXH1 Proteins at

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days

FOXH1 Proteins by Origin and Source

Origin Expressed in Conjugate

Mouse (Murine)

More Proteins for Forkhead Box H1 (FOXH1) Interaction Partners

Human Forkhead Box H1 (FOXH1) interaction partners

  1. These results indicate that Smad4 (show SMAD4 Proteins) acts as a tumor suppressor by activating FOXH1, and then suppressing the expression of estrogen receptor (show ESR1 Proteins), in addition to tumor migration and invasion.

  2. HEB (show TCF12 Proteins) and E2A (show TCF3 Proteins)-bind the SCA motif at regions overlapping SMAD2 (show SMAD2 Proteins)/3 and FOXH1

  3. Four genetic variants are found in FOXH1 that are associated with ventricular septal defects in Chinese patients.

  4. Results suggest that PKA can negatively regulate ERalpha (show ESR1 Proteins), at least in part, through FoxH1.

  5. This work suggests that FAST-1 may participate in the vascular smooth muscle response to injury and may represent a potential molecular target for modulating the progression of cardiac allograft vasculopathy.

  6. Smad (show SMAD1 Proteins)-binding peptide (show HP Proteins) aptamer FOXH1 can be developed to selectively inhibit TGF-beta (show TGFB1 Proteins)-induced gene expression.

  7. These results demonstrate for a functional role for TGF-beta (show TGFB1 Proteins) ligands in regulation of mammalian Mixl1 (show MIXL1 Proteins), identify FoxH1 as an essential co-activator, and implicate Nodal as the embryonic regulator of Mixl1 (show MIXL1 Proteins) in mesendoderm morphogenesis.

  8. FoxH1 has a role in androgen receptor (show AR Proteins)-mediated transactivation

  9. Reduced NODAL signaling via mutation of several pathway members including FOXH1 is linked to heart defects and holoprosencephaly.

Mouse (Murine) Forkhead Box H1 (FOXH1) interaction partners

  1. that FAST2 is expressed in a cell-specific manner during ovarian follicle development

  2. The finding that Foxh1-Grg (show AES Proteins)-mediated repression is not essential for Nodal expression during mouse embryogenesis suggests that other regulators compensate for the loss of repressive regulatory input that is mediated by Grg (show AES Proteins) interactions.

  3. Formation of midgut and hindgut definitive endoderm is unaffected by loss of Foxh1 or Foxa2 (show FOXA2 Proteins).

  4. A conserved intronic enhancer (ASE (show ARSE Proteins)), containing binding sites for the fork head (show FOXA1 Proteins) transcription factor Foxh1, modulates dynamic patterns of Nodal expression during early mouse development.

  5. Foxh1 and Nkx2-5 (show NKX2-5 Proteins) functionally interact and are essential for development of the anterior heart field and its derivatives

  6. As goosecoid (show GSC Proteins) is itself induced in a Foxh1-dependent manner, we propose that Foxh1 initiates positive and negative transcriptional circuits to refine cell fate decisions during gastrulation

  7. Foxh1 initiates a transcriptional regulatory network within the developing anterior neuroectoderm.

Zebrafish Forkhead Box H1 (FOXH1) interaction partners

  1. we identify a previously unappreciated role for the Nodal-transcription factor FoxH1 in mediating cell responsiveness to Bmp further linking the control of these two pathways in the heart

  2. Axial mesoderm induction is differentially disrupted in FoxH1 mutants. FoxH1 mutants respond differently to Activin-like signaling.

  3. These results and the association of FoxH1 and Mixer/Bon with phosphorylated Smad2 (show SMAD2 Proteins) support a role for these factors as components of the Nodal signaling pathway.

  4. flk1 (show KDR Proteins) is a direct target of FoxH1; FoxH1 is involved in vessel formation in zebrafish.

  5. to an essential role for maternal FoxH1 and downstream keratins during gastrulation that is epistatic to Nodal signaling

FOXH1 Protein Profile

Protein Summary

FOXH1 encodes a human homolog of Xenopus forkhead activin signal transducer-1. FOXH1 protein binds SMAD2 and activates an activin response element via binding the DNA motif TGT(G/T)(T/G)ATT.

Gene names and symbols associated with Forkhead Box H1 Proteins (FOXH1)

  • forkhead box H1 (FOXH1)
  • forkhead box H1 (foxh1)
  • forkhead box H1 (LOC100301631)
  • forkhead box H1 (Foxh1)
  • fast protein
  • FAST-1 protein
  • fast-2 protein
  • Fast1 protein
  • Fast2 protein
  • fe26b06 protein
  • FOXH1 protein
  • foxh1a protein
  • schmalspur protein
  • SUR protein
  • wu:fe26b06 protein
  • wu:fi30c08 protein
  • wu:fi32b01 protein
  • XFast-1 protein
  • xfast1 protein
  • xfoxh1 protein

Protein level used designations for Forkhead Box H1 Proteins (FOXH1)

forkhead box H1 , forkhead activin signal transducer 1 , forkhead box protein H1 , forkhead box protein H1-like , TGF-beta/activin signal transducer , fast-2 , forkhead activin signal transducer 2 , forkhead activin signal transducer-1 , hFAST-1 , FAST1 transcription factor , XFoxH1a , fast-1 , xFAST-1 , etID62177.12 , uncle freddy , unf

464468 Pan troglodytes
482098 Canis lupus familiaris
549838 Xenopus (Silurana) tropicalis
100456146 Pongo abelii
100598441 Nomascus leucogenys
100301631 Oryzias latipes
8928 Homo sapiens
14106 Mus musculus
300054 Rattus norvegicus
398070 Xenopus laevis
57930 Danio rerio
493733 Bos taurus
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