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Forkhead Box I1 Proteins (FOXI1)

FOXI1 belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. Additionally we are shipping FOXI1 Antibodies (102) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FOXI1 2299 Q12951
FOXI1 14233 Q922I5
Rat FOXI1 FOXI1 287185  
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Top FOXI1 Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,992.00
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$3,023.17
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HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
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HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

FOXI1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Forkhead Box I1 (FOXI1) Interaction Partners

Zebrafish Forkhead Box I1 (FOXI1) interaction partners

  1. Data indicate that foxi1 is expressed in branchial arch ectoderm and endoderm, and morpholino knock-down of foxi1 causes apoptosis of neural crest in the branchial arches, which is rescued by fgf3 (show FGF3 Proteins).

  2. Foxi1 and Dlx3b/4b regulate the neuronal and sensory lineages of the inner ear.

  3. pax8 (show PAX8 Proteins) works with related genes pax2a/pax2b to downregulate otic expression of foxi1, a necessary step for further otic development

  4. Data show that the hearsay mutation disrupts foxi1, a forkhead domain-containing gene, expressed in otic precursor cells before placodes become visible, and which appears to be the earliest marker known for the otic anlage.[foxi1]

  5. Foxi1 is necessary for pax8 (show PAX8 Proteins) expression in the otic placode allowing fgf3 (show FGF3 Proteins)/8 activation and also for pax8 (show PAX8 Proteins) expression in the pharyngeal pouchs. Foxi1 is also necessary to maintain fgf3 (show FGF3 Proteins) expression in the pharyngeal pouchs.

  6. FoxI1 is capable of remodeling chromatin higher-order structure and can stably create site-specific changes in chromatin to either stably create or remove DNase I (show DNASE1 Proteins) hypersensitive sites.

  7. Foxi1 provide competence for cells to respond to Fgf and form an otic placode

Human Forkhead Box I1 (FOXI1) interaction partners

  1. We found no evidence for a significant association between mutations of KCNJ10 (show KCNJ10 Proteins) and FOXI1 with SLC26A4 (show SLC26A4 Proteins) in Pendred syndrome/enlarged vestibular aqueducts.

  2. No FOXI1 mutations were present in bilateral deafness patients with inner ear malformation.

  3. SLC26A4 (show SLC26A4 Proteins), FOXI1 and KCNJ10 (show KCNJ10 Proteins) are not major determinants in unilateral deafness and enlarged vestibular aqueduct

  4. C/EBP alpha (show CEBPA Proteins) and HNF-3 gamma (show FOXA3 Proteins) cooperatively regulate CYP3A4 (show CYP3A4 Proteins) expression in hepatic cells by a mechanism that probably involves chromatin remodeling.

  5. Data suggestthat Foxi1 is necessary for expression of at least four subunits in three different epithelia and most likely is a major determinant for proper assembly of a functional vacuolar H(+)-ATPase (show ATP6V1B2 Proteins) complex at these locations.

Mouse (Murine) Forkhead Box I1 (FOXI1) interaction partners

  1. mutations in FOXI1 could prove to cause a Pendred syndrome-like human deafness

  2. examined the expression patterns of the Foxi class genes from embryonic day 6.5 to 10.5; Foxi1 expression is first detected in the endolymphatic duct in the otic vesicle at E10.5

  3. The AE4 promoter is identified as a direct target of Foxi1.

  4. Spermatozoa from Foxi1 null males fail to reach the female genital tract in sufficient number to allow fertilization.

  5. Data suggestthat Foxi1 is necessary for expression of at least four subunits in three different epithelia and most likely is a major determinant for proper assembly of a functional vacuolar H(+)-ATPase (show ATP6V1B2 Proteins) complex at these locations.

  6. Foxa1 (show FOXA1 Proteins) and Foxi1 are required for later stage sweat gland development.

Xenopus laevis Forkhead Box I1 (FOXI1) interaction partners

  1. Foxi2 thus acts as a link between the oocyte and the early pathway to ectoderm

  2. Xema is both necessary and sufficient for the inhibition of ectopic mesendoderm in the cells of the presumptive ectoderm

FOXI1 Protein Profile

Protein Summary

This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined\; however, it is possible that this gene plays an important role in the development of the cochlea and vestibulum, as well as embryogenesis. Mutations in this gene may be associated with the common cavity phenotype. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Forkhead Box I1 Proteins (FOXI1)

  • forkhead box I3b (foxi3b)
  • forkhead box I1 (foxi1)
  • forkhead box I1 (FOXI1)
  • forkhead box protein I1 (CC1G_14832)
  • forkhead box I1 (Foxi1)
  • forkhead box i1 (foxi1)
  • 5830401E05Rik protein
  • cb724 protein
  • ema protein
  • Fkh10 protein
  • FKHL10 protein
  • foo protein
  • FOXI1 protein
  • foxi1a protein
  • foxi1e protein
  • FREAC-6 protein
  • FREAC6 protein
  • HFH-3 protein
  • Hfh3 protein
  • xema protein
  • xfoxi1 protein
  • Xfoxi1a protein

Protein level used designations for Forkhead Box I1 Proteins (FOXI1)

forkhead box protein I1 , Xenopus ectodermally-expressed mesendoderm antagonist , ectodermally-expressed mesendoderm antagon , ectodermally-expressed mesendoderm antagonist , forkhead box protein I1-ema , foxI1-ema , foxI3 , forkhead box I1 , forkhead box protein I1-like , HNF-3/fork-head homolog 3 , HNF-3/fork-head homolog-3 , forkhead-like 10 , forkhead-related activator 6 , forkhead-related protein FKHL10 , forkhead-related transcription factor 6 , hepatocyte nuclear factor 3 forkhead homolog 3 , HNF-3/forkhead homolog 3 , forkhead homolog 10 , hearsay , hsy , no soul , nos , quadro , quo(l)

GENE ID SPECIES
387258 Danio rerio
394546 Xenopus (Silurana) tropicalis
471732 Pan troglodytes
700122 Macaca mulatta
9379322 Coprinopsis cinerea okayama7130
100397090 Callithrix jacchus
100455511 Pongo abelii
2299 Homo sapiens
539442 Bos taurus
14233 Mus musculus
287185 Rattus norvegicus
380059 Xenopus laevis
427613 Gallus gallus
353313 Danio rerio
489127 Canis lupus familiaris
100511481 Sus scrofa
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