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Transcriptional regulator that binds to the upstream enhancer region (CCAC box) of myoglobin gene. Additionally we are shipping Foxk1 Antibodies (39) and and many more products for this protein.
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Foxk1 and Foxk2 (show FOXK2 ELISA Kits) are identified as transcriptional repressors of autophagy in muscle cells and fibroblasts.
in the developing eyes, Foxk1 protein is localized in bipolar, amacrine and ganglion cells with an onset of Foxk1 expression from E15 onwards; expression pattern during development suggests that Foxk1 may have an important role in retinal cells
Foxk1 promotes muscle progenitor cell proliferation by repressing Foxo4 transcriptional activity and inhibits myogenic differentiation by repressing Mef2 activity.
the transcriptional repression of Foxk1 is dependent on the Sin3-Sds3 (show SUDS3 ELISA Kits) repression complex, and knockdown of Sds3 (show SUDS3 ELISA Kits) results in cell-cycle arrest.
Foxk1 interacts with Sin3 through the N-terminal sin3 interacting domain
Collectively, these studies define a Fhl2 (show FHL2 ELISA Kits)-Foxk1 cascade that regulates the myogenic progenitor cell activity in adult skeletal muscle and enhances our understanding of muscle regeneration.
NMR study of DNA-binding domain of myocyte nuclear factor (Foxk1)
These studies demonstrate that Sox15 (show SOX15 ELISA Kits), Fhl3 (show FHL3 ELISA Kits) and Foxk1 function to coordinately regulate the myogenic progenitor cell population and skeletal muscle regeneration.
These findings implicate FOXK1 (show FOXK2 ELISA Kits) as a cell cycle and growth modulator that inhibits apoptosis in colon cancer cells. FOXK1 (show FOXK2 ELISA Kits)-shRNA may serve as a novel and potent therapeutic agent, alone or with 5-FU, against colon cancer
Data indicated the function of Foxk1 (show FOXK2 ELISA Kits) as a tumor suppressor in facilitating angiogenesis and metastasis in breast cancer.
FOXK1 (show FOXK2 ELISA Kits) protein levels and activity are regulated by associating with JLP (show SPAG9 ELISA Kits) and PLK1 (show PLK1 ELISA Kits)
Overall, these results demonstrate a novel role for FOXK1 (show FOXK2 ELISA Kits) in regulating the expression of antiviral genes via Nup98 (show NUP98 ELISA Kits), from insects to humans.
FOXK1 (show FOXK2 ELISA Kits) and FOXK2 (show FOXK2 ELISA Kits) positively regulate Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling by translocating dishevelled (show DVL2 ELISA Kits) proteins into the nucleus.
FOXK1 (show FOXK2 ELISA Kits) binds to the promoter and regulates expression of DHFR (show DHFR ELISA Kits), TYMS (show TYMS ELISA Kits), GSDMD (show GSDMD ELISA Kits), and the E2F (show E2F1 ELISA Kits) binding partner TFDP1 (show TFDP1 ELISA Kits).
Transcriptional regulator that binds to the upstream enhancer region (CCAC box) of myoglobin gene. Has a role in myogenic differentiation and in remodeling processes of adult muscles that occur in response to physiological stimuli.
forkhead box K1
, forkhead box protein K1
, myocyte nuclear factor
, winged helix protein CWH-5
, forkhead box protein K2
, interleukin enhancer-binding factor 1