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Forkhead Box P3 Proteins (FOXP3)

The protein encoded by FOXP3 is a member of the forkhead/winged-helix family of transcriptional regulators. Additionally we are shipping FOXP3 Antibodies (513) and FOXP3 Kits (41) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FOXP3 50943 Q9BZS1
FOXP3 20371 Q99JB6
FOXP3 317382  
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Top FOXP3 Proteins at

Showing 10 out of 20 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Mouse His tag,GST tag 100 μg Log in to see 11 to 13 Days
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 11 Days
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
HOST_Escherichia coli (E. coli) Human T7 tag,His tag   100 μg Log in to see 11 to 13 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
HOST_Escherichia coli (E. coli) Cow Un-conjugated   5 applications Log in to see 1 to 2 Days
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 16 Days

FOXP3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)
Rat (Rattus)

Top referenced FOXP3 Proteins

  1. Human FOXP3 Protein expressed in Wheat germ - ABIN1354393 : Liu, Liu, Chen, Yang, Liu, Liu, Dugas, Tang, Zheng, Liu, Wang: FOXP3 Controls an miR-146/NF-?B Negative Feedback Loop That Inhibits Apoptosis in Breast Cancer Cells. in Cancer research 2015 (PubMed)

  2. Human FOXP3 Protein expressed in Human - ABIN2721384 : Larsen, Munir, Woetmann, Frøsig, Odum, Svane, Becker, Andersen: Functional characterization of Foxp3-specific spontaneous immune responses. in Leukemia 2013 (PubMed)

More Proteins for Forkhead Box P3 (FOXP3) Interaction Partners

Zebrafish Forkhead Box P3 (FOXP3) interaction partners

  1. analysis of Foxp3-based immunoregulation and autoimmunity in zebrafish

  2. correlation between the expression of t-bet, stat6 (show STAT6 Proteins) and foxp3 with other genes involved in Th and T(reg (show KCNH2 Proteins)) responses

Atlantic Salmon (Salmo salar) Forkhead Box P3 (FOXP3) interaction partners

  1. cloning and characterization of the full-length cDNA of Atlantic salmon Foxp3, which possesses a Forkhead domain, a zinc finger domain and a leucine-zipper domain as its counterpart in mammals

Human Forkhead Box P3 (FOXP3) interaction partners

  1. The frequency of FOXP3+CD8 (show CD8A Proteins)+ Treg was variable, without a statistically significant association with age or EBV status.

  2. this study show that FoxP3 polymorphisms could be a potential contributor for the development of preeclampsia in Iranian women

  3. FOXP3 can regulate the expression of ARHGAP15 and affects migration of glioma cells through the Rac1 signaling pathway

  4. Single nucleotide polymorphisms in the FOXP3 gene are associated with increased risk of relapsing-remitting multiple sclerosis in Iranian patients.

  5. Efficiently downregulated the percentages of CD4 (show CD4 Proteins)+CD25 (show IL2RA Proteins)+Foxp3+ regulator T (Treg) cells.

  6. By screening the signalling pathways, we observed an obvious upregulation of phosphorylated NF-kappaB (show NFKB1 Proteins) in A549 and H520 cells after silencing of FOXP3. Our results suggest that Foxp3 suppressed NSCLC cell metastasis, at least partially, via NF-kappaB (show NFKB1 Proteins) signaling.

  7. Our study demonstrated the tacrolimus-induced acute nephrotoxicity was associated with FOXP3 rs3761548 polymorphism in renal transplant patients

  8. CD44 (show CD44 Proteins) has a regulatory role in FOXP3 expression and is associated with good prognostic factors in breast cancer

  9. CsA (show ERCC8 Proteins) and RAPA (show TRERF1 Proteins) did not interfere with the suppressor properties of human CD8 (show CD8A Proteins)(+)CD28 (show CD28 Proteins)(-) T cells in vitro, although they affected the expression of the FOXP3 molecule

  10. FOXP3 was expressed in lung adenocarcinoma tissue and A549 cells. FOXP3 inhibition decreased cell proliferation, migration, and invasion as well as the secretion of inhibitory cytokines. It enhanced lung adenocarcinoma cell proliferation via upregulating the levels of the cell cycle G1/S checkpoint gene CCND1 (show CCND1 Proteins).

Mouse (Murine) Forkhead Box P3 (FOXP3) interaction partners

  1. Study highlights the importance of IL-23R (show IL23R Proteins) expression level and the instability of Foxp3+ regulatory T cells in the development of inflammatory bowel diseases.

  2. indirubin administration effectively suppressed CD4 (show CD4 Proteins)(+) T cell infiltration in the colon of DSS (show PMP22 Proteins)-induced UC mice and promoted the generation of Foxp3-expressing regulatory T cells

  3. The data suggest that RORgt expression in Tregs contributes to an optimal suppressive capacity during gut (show GUSB Proteins)-specific immune responses, rendering Foxp3-RORgt T cells as an important effector Treg subset in the intestinal system.

  4. The ex vivo expression of transforming growth factor (TGF)-beta (show TGFB1 Proteins) and factor Foxp3 were significantly higher in splenocytes of the experimental mice than the basal expression observed in the control cells.

  5. These observations reveal an unexpected differential role of DJ-1 (show PARK7 Proteins) in the development of nTregs and iTregs.

  6. An IL-27 (show IL27 Proteins)/Lag3 (show LAG3 Proteins) axis enhances Foxp3+ regulatory T cell-suppressive function and therapeutic efficacy.

  7. the presence of IL-2 (show IL2 Proteins) during the in vitro generation of iTreg cells confers resistance to Th17 conversion but that IL-2 (show IL2 Proteins) and retinoic acid (RA) cooperate to maintain Foxp3 expression following stimulation under Th17-polarizing conditions

  8. Foxp3 has a rapid turn over in Treg partly controlled at the transcriptional level by the JAK (show JAK3 Proteins)/STAT (show STAT1 Proteins) pathway

  9. NZW Tregs were less sensitive to limiting doses of trophic cytokines, IL-2 (show IL2 Proteins) and -33, for population homeostasis and for maintenance of FoxP3 expression

  10. Data show that tubacin can upregulate forkhead box P3 protein (Foxp3) expression of CD4 (show CD4 Proteins)(+) CD25 (show IL2RA Proteins)(+) Tregs and enhances their cellular immunosuppressive capability.

Pig (Porcine) Forkhead Box P3 (FOXP3) interaction partners

  1. sequenced the entire Foxp3 cDNA which is 1296 nucleotides in length and codes for a polypeptide of 432 amino acids

  2. In a miniature swine lung transplantation model, the FOXP3 mRNA level in the peripheral blood was upregulated at an early phase of rejection

Cow (Bovine) Forkhead Box P3 (FOXP3) interaction partners

  1. Experimental infection with bovine viral diarrhea virus did not provide evidence ofTreg activation based on expression of FoxP3 and CTLA4 (show CTLA4 Proteins).

  2. The expression of Foxp3 in CD4 (show CD4 Proteins)(+) T cells from persistent lymphocytotic cattle was significantly increased.

  3. There is a positive correlation between the intensity of CD25 (show IL2RA Proteins) expression and the expression of the transcription Foxp3 factor in bovine CD8 (show CD8A Proteins)(+) cells.

  4. identification of Foxp3 expression in Treg cells

  5. These findings revealed that despite the existence of a distinct bovine CD4 (show CD4 Proteins)(+)CD25 (show IL2RA Proteins)(high) T cell population, which showed Foxp3 transcription/expression, natural regulatory activity did not reside in this cell population

Horse (Equine) Forkhead Box P3 (FOXP3) interaction partners

  1. The correlation of TH17-related TLR4 (show TLR4 Proteins) expression and Foxp3-positive cells in the rectal tissue of horses with inflammatory bowel disease is reported.

  2. Expression levels of FOXP3 mRNA copy numbers were significantly increased in lesional compared to tumour-distant samples. There was no difference in FOXP3 expression in tumour-distant samples from equine sarcoid- compared with control horses.

  3. results confirm FoxP3 expression in the horse, in contrast to the mouse, is regulated similarly to FOXP3 expression in humans and provide evidence that FoxP3 expression by conventional T cells may help regulate the developing immune response

FOXP3 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with Forkhead Box P3 Proteins (FOXP3)

  • forkhead box P3 (FOXP3)
  • forkhead box P3a (foxp3a)
  • forkhead box P3 (LOC100348270)
  • forkhead box P3 (foxp3)
  • transcription factor foxp3 (foxp3)
  • forkhead box P3 (Foxp3)
  • AIID protein
  • DIETER protein
  • FOXP3 protein
  • IPEX protein
  • JM2 protein
  • PIDX protein
  • RGD1562112 protein
  • scurfin protein
  • sf protein
  • XPID protein

Protein level used designations for Forkhead Box P3 Proteins (FOXP3)

forkhead box protein P3 , regulatory protein Foxp3 , scurfin , forkhead box P3 , forkhead box protein P3-like , transcription factor foxp3 , FOXP3delta7 , immune dysregulation, polyendocrinopathy, enteropathy, X-linked , immunodeficiency, polyendocrinopathy, enteropathy, X-linked , scurfy , forkhead/winged helix transcription factor 3

574303 Macaca mulatta
571165 Danio rerio
740909 Pan troglodytes
100037405 Felis catus
100348270 Oryctolagus cuniculus
100467988 Ailuropoda melanoleuca
100526661 Salmo salar
100158268 Xenopus laevis
50943 Homo sapiens
491876 Canis lupus familiaris
20371 Mus musculus
444998 Sus scrofa
506053 Bos taurus
317382 Rattus norvegicus
100052226 Equus caballus
100735602 Cavia porcellus
100240742 Ovis aries
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