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The protein encoded by FTCD is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Additionally we are shipping FTCD Proteins (10) and FTCD Kits (5) and many more products for this protein.
Showing 10 out of 45 products:
Human Monoclonal FTCD Primary Antibody for IF, WB - ABIN395776
Jugessur, Shi, Gjessing, Lie, Wilcox, Weinberg, Christensen, Boyles, Daack-Hirsch, Nguyen, Christiansen, Lidral, Murray: Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. in PLoS ONE 2010
Show all 5 references for ABIN395776
Human Monoclonal FTCD Primary Antibody for WB - ABIN396610
Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010
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Chicken Polyclonal FTCD Primary Antibody for IHC, WB - ABIN2776887
Hilton, Christensen, Watkins, Raby, Renaud, de la Luna, Estivill, MacKenzie, Hudson, Rosenblatt: The molecular basis of glutamate formiminotransferase deficiency. in Human mutation 2003
Show all 2 references for ABIN2776887
Chicken Polyclonal FTCD Primary Antibody for IHC, WB - ABIN2776888
Hillman, Green, Brenner: An unappreciated role for RNA surveillance. in Genome biology 2004
FTCD is a positive regulator of the hypoxia-HIF signaling pathway and has an important role in cell proliferation, metabolism and migration in HepG2 cells
The FTCD promoter is activated by serum depletion according to promoter reporter assays in HEK (show EPHA3 Antibodies) 293 cells.
Scyl1 (show CCL13 Antibodies) interacts with 58K/formiminotransferase cyclodeaminase (FTCD) and golgin p115 (show ARHGAP4 Antibodies), and is required for the maintenance of Golgi morphology
Disease-causing mutations have been identified in the FTCD gene in three patients with the putative autosomal recessive disorder glutamate formiminotransferase deficiency.
Autoreactive B cell response against formiminotransferase-cyclodeaminase correlated with disease activity, possibly linking B-cell autoreactivity and AIH pathogenesis
The protein encoded by this gene is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Mutations in this gene are associated with glutamate formiminotransferase deficiency. Alternatively spliced transcript variants have been found for this gene.
, 58 kDa microtubule-binding protein
, glutamate formiminotransferase