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Formin 2 (FMN2) ELISA Kits

Formin homology (FH) domain proteins (see FMN1\; MIM 136535) play a role in cytoskeletal organization and/or establishment of cell polarity.[supplied by OMIM, Apr 2010].. Additionally we are shipping Formin 2 Antibodies (26) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human FMN2 FMN2 56776 Q9NZ56
Anti-Mouse FMN2 FMN2 54418 Q9JL04
Anti-Rat FMN2 FMN2 289262  
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More ELISA Kits for Formin 2 Interaction Partners

Human Formin 2 (FMN2) interaction partners

  1. Disease causing mutations in inverted formin 2 (show INF2 ELISA Kits) regulate its binding to G-actin (show ACTB ELISA Kits), F-actin capping protein (CapZ (show CAPZB ELISA Kits) alpha-1 (show CAPZA1 ELISA Kits)) and profilin 2 (show PFN2 ELISA Kits).

  2. This DNA damage-induced nuclear actin assembly requires two biologically and physically linked nucleation factors: Formin-2 and Spire-1 (show SPIRE1 ELISA Kits)/Spire-2.

  3. We therefore characterized co-expressed Spir-2 (show SPIRE1 ELISA Kits) and Fmn-2 fluorescent protein fusions . The data corroborate a model according to which Spir-2 (show SPIRE1 ELISA Kits) exists in two different states, a cytosolic monomeric conformation and a membrane-bound state

  4. FMN2 mutations link intellectual disability either directly or indirectly to the regulation of actin-mediated synaptic spine density.

  5. miR-335 regulates the expression of at least five formin family members, three of which are validated, FMNL3, FMN2 and DAAM2.

  6. FMN2 is a crucial protein involved in the control of p21 (show CDKN1A ELISA Kits).

  7. results identify FMN2 as a crucial component in the regulation of p21 (show CDKN1A ELISA Kits) and consequent oncogene (show RAB1A ELISA Kits)/stress-induced cell-cycle arrest in human cells.

  8. analysis of the molecular basis of the Spir1/formin-2 interaction

  9. FMN2 was characterized at human chromosome 1q43.

  10. It is likely that FMN2 has the same function as Fmn2 in the mouse, i.e., maintenance of the meiotic spindle. Identification of patients with meiosis I arrest is necessary to determine whether FMN2 mutations are a cause of unexplained infertility.

Mouse (Murine) Formin 2 (FMN2) interaction partners

  1. Fmn2 as a mediator of actin bundle integrity, enabling efficient force transmission to the adhesion sites.

  2. Data suggest formin homology domain (FH2) of Fmn2 binds actin at filament barbed end as weak capper and plays a role in displacing WASP homology domain 2 (WH2) domains of Spire-1 from actin; competitive binding of Fmn2 vs Spire-1 aids actin assembly.

  3. Spire recruits Fmn2 and facilitates its association with actin filaments barbed ends.

  4. Results suggest that the regulation of microtubule acetylation is likely a general formin (show FMN1 ELISA Kits) activity.

  5. analysis of the molecular basis of the Spir1/formin-2 interaction

  6. Spire1 (show SPIRE1 ELISA Kits) and Spire2 cooperate with Formin-2 (Fmn2) to nucleate actin filaments in mouse oocytes.

  7. High formin 2 levels at meiosis I entry induce meshwork maintenance, leading to equal forces being exerted on the chromosomes, preventing spindle migration.

  8. Gene profiling of Fmn2 in Graffi murine leukemia virus-induced lymphoid leukemias suggest its important role in leukemogenesis.

  9. Fmn2 is a candidate in a QTL hotspot associated with neurobehavioral traits and gene expression in the mouse brain. Hippocampal pyramidal neurons exhibit distinct and fine granular immunoreactivity for FMN2.

  10. formin-2 is a maternal-effect (show NLRP5 ELISA Kits) gene that is expressed in oocytes and is required for progression through metaphase of meiosis I

Formin 2 (FMN2) Antigen Profile

Antigen Summary

Formin homology (FH) domain proteins (see FMN1\; MIM 136535) play a role in cytoskeletal organization and/or establishment of cell polarity.

Gene names and symbols associated with Formin 2 (FMN2) ELISA Kits

  • formin 2 (PVX_123615) antibody
  • formin 2 (PKH_143610) antibody
  • formin 2 (FMN2) antibody
  • formin 2 (Fmn2) antibody
  • AU024104 antibody

Protein level used designations for Formin 2 (FMN2) ELISA Kits

formin 2 , formin-2

5476594 Plasmodium vivax Sal-1
7323284 Plasmodium knowlesi strain H
56776 Homo sapiens
54418 Mus musculus
775973 Gallus gallus
490366 Canis lupus familiaris
289262 Rattus norvegicus
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