anti-Formin Binding Protein 1-Like (FNBP1L) Antibodies

The protein encoded by FNBP1L binds to both CDC42 and N-WASP. Additionally we are shipping FNBP1L Proteins (4) and FNBP1L Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FNBP1L 54874 Q5T0N5
FNBP1L 214459 Q8K012
FNBP1L 310839 Q2HWF0
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Top anti-FNBP1L Antibodies at antibodies-online.com

Showing 10 out of 60 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of FNBP1L Antibody  in mouse lung tissue lysates (35ug/lane). This demonstrates the FNBP1L antibody detected the FNBP1L protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB FNBP1L Antibody (Center)  western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the FNBP1L antibody detected the FNBP1L protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: FNBP1L Antibody [NBP1-76845] - Human brain tissue with FNBP1L antibody at 2.5 ug/ml. Immunocytochemistry/Immunofluorescence: FNBP1L Antibody [NBP1-76845] - Immunofluorescence of TOCA-1 in Human Brain cells with TOCA-1 antibody at 20 ug/mL. 0.1 mg Log in to see 8 to 11 Days
$447.56
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: FNBP1L Antibody [NBP1-76846] - Human Brain cells. Western Blot: FNBP1L Antibody [NBP1-76846] - Human brain tissue lysate in (A) the absence and (B) the presence of blocking peptide with FNBP1L antibody at 0.5 ug/mL. 0.1 mg Log in to see 8 to 11 Days
$447.56
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Human Kidney (formalin-fixed, paraffin-embedded) stained with FNBP1L antibody ABIN461907 at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Liver (formalin-fixed, paraffin-embedded) stained with FNBP1L antibody ABIN461907 at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7 to 9 Days
$451.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$537.17
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: FNBP1L Antibody [NBP1-80569] - Human lung carcinoma. Antibody used at a dilution of 1:1,000 (1ug/mg). Western Blot: FNBP1L Antibody [NBP1-80569] - Whole cell lysate from Jurkat (15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 mcg) and HeLa (H; 50 mcg) cells. Antibodies: Affinity purified rabbit anti-Toca-1 antibody used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 6 mcg/mg lysate. Toca-1 was also immunoprecipitated by rabbit anti-Toca-1 antibody NBP1-80563 which recognizes an upstream epitope. 100 μL Log in to see 7 to 9 Days
$486.94
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL Log in to see 7 to 9 Days
$793.83
Details

FNBP1L Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against FNBP1L Interaction Partners

Xenopus laevis Formin Binding Protein 1-Like (FNBP1L) interaction partners

  1. This suggests that TOCA1 binding to Cdc42 is an early step in the Cdc42-dependent pathways that govern actin dynamics, and the differential binding affinities of the effectors facilitate a handover from TOCA1 to N-WASP, which can then drive recruitment of the actin-modifying machinery.

Human Formin Binding Protein 1-Like (FNBP1L) interaction partners

  1. This suggests that TOCA1 binding to Cdc42 is an early step in the Cdc42-dependent pathways that govern actin dynamics, and the differential binding affinities of the effectors facilitate a handover from TOCA1 to N-WASP, which can then drive recruitment of the actin-modifying machinery.

  2. Loss of p53 tumor suppressor (show TP53 Antibodies) function in breast cancers leads to upregulation of Toca-1, and results in enhanced risk of developing metastatic disease.

  3. GWAS results show that the aggregate effects of common SNPs explain 22-46% of phenotypic variation in childhood intelligence in the three largest cohorts; FNBP1L was also significantly associated with childhood intelligence

  4. findings suggest that Toca-1 functions at an early step in the dissemination of metastatic breast tumor cells; taken together, results identify Toca-1 as a proinvasive protein in breast adenocarcinoma

  5. Toca-1 knockdown cells also display a significant defect in EGF (show EGF Antibodies)-induced motility and invasiveness.

  6. Cdc42 (show CDC42 Antibodies) may influence endocytic membrane trafficking by regulating the formation and activity of the Toca-1/N-WASP (show WASL Antibodies) complex.

  7. Toca-1 promotes actin nucleation by activating the N-WASP (show WASL Antibodies)-WIP/CR16 (show WIPF2 Antibodies) complex, the predominant form of N-WASP (show WASL Antibodies) in cells.

  8. a vesicle trafficking regulator Toca-1 regulates different aspects of neuronal morphology from N-WASP (show WASL Antibodies)

  9. We show that actin tail initiation by S. flexneri requires Toca-1 for the conversion of N-WASP (show WASL Antibodies) from a closed inactive conformation to an open active one.

  10. the Toca-1-N-WASP (show WASL Antibodies) complex can link filopodial formation to endocytosis

Mouse (Murine) Formin Binding Protein 1-Like (FNBP1L) interaction partners

  1. Toca-1(knockdown) cells have defects in formation of myotubes probably due to reduced activity of actin cytoskeleton regulators such as N-WASP (show WASL Antibodies).

FNBP1L Antigen Profile

Protein Summary

The protein encoded by this gene binds to both CDC42 and N-WASP. This protein promotes CDC42-induced actin polymerization by activating the N-WASP-WIP complex and, therefore, is involved in a pathway that links cell surface signals to the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with FNBP1L

  • formin binding protein 1-like (FNBP1L) antibody
  • formin binding protein 1-like (fnbp1l) antibody
  • formin binding protein 1-like (Fnbp1l) antibody
  • formin-binding protein 1-like (LOC100909995) antibody
  • 2610318I01Rik antibody
  • AW548221 antibody
  • C1orf39 antibody
  • MGC132162 antibody
  • RGD1305386 antibody
  • toca-1 antibody
  • TOCA1 antibody
  • zgc:100923 antibody

Protein level used designations for FNBP1L

formin binding protein 1-like , formin-binding protein 1-like , transducer of Cdc42-dependent actin assembly-1 , toca-1 , transducer of Cdc42-dependent actin assembly 1 , transducer of Cdc42-dependent actin assembly protein 1 , Cdc42 effector

GENE ID SPECIES
424495 Gallus gallus
445240 Danio rerio
448740 Xenopus (Silurana) tropicalis
469385 Pan troglodytes
479942 Canis lupus familiaris
616665 Bos taurus
713578 Macaca mulatta
735241 Xenopus laevis
100032840 Monodelphis domestica
100059052 Equus caballus
100077332 Ornithorhynchus anatinus
100157977 Sus scrofa
100338578 Oryctolagus cuniculus
100405015 Callithrix jacchus
100448000 Pongo abelii
100476131 Ailuropoda melanoleuca
100559983 Anolis carolinensis
54874 Homo sapiens
214459 Mus musculus
310839 Rattus norvegicus
100909995 Rattus norvegicus
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