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FMNL2 encodes a formin-related protein. Additionally we are shipping FMNL2 Proteins (4) and FMNL2 Kits (2) and many more products for this protein.
Showing 10 out of 29 products:
Human Monoclonal FMNL2 Primary Antibody for ELISA, WB - ABIN566725
Zhu, Liang, Ding: Overexpression of FMNL2 is closely related to metastasis of colorectal cancer. in International journal of colorectal disease 2008
Show all 5 references for ABIN566725
Human Polyclonal FMNL2 Primary Antibody for ICC, IF - ABIN4312213
Gardberg, Talvinen, Kaipio, Iljin, Kampf, Uhlen, Carpén: Characterization of Diaphanous-related formin FMNL2 in human tissues. in BMC cell biology 2010
Show all 2 references for ABIN4312213
Human Polyclonal FMNL2 Primary Antibody for WB - ABIN2783099
Colland, Jacq, Trouplin, Mougin, Groizeleau, Hamburger, Meil, Wojcik, Legrain, Gauthier: Functional proteomics mapping of a human signaling pathway. in Genome research 2004
miR (show MLXIP Antibodies)-206 functioned as a tumor suppressor in the progression of colorectal cancer(CRC (show CALR Antibodies)) by targeting FMNL2 and c-MET. Restoration of miR (show MLXIP Antibodies)-206 expression may represent a promising therapeutic approach for targeting malignant CRC (show CALR Antibodies).
Capping protein and FMNL2 functionally coregulate filament barbed-end assembly.
The two interacting FMNL-Cdc42 heterodimers expose six membrane interaction motifs on a convex protein surface, the assembly of which may facilitate actin filament elongation at the leading edge of lamellipodia and filopodia.
These data establish a role for FMNL2 in the regulation of beta1-integrin and provide a mechanistic understanding of the function of FMNL2 in cancer invasiveness.
MiR-34a was down-regulated in colorectal cancer cells and inversely correlated with FMNL2 and E2F5 expressions. Our study suggests that miR-34a is an important tumor suppressor of CRC progression by targeting FMNL2 and E2F5.
Rac1-induced actin assembly and subsequent AJ formation critically depends on FMNL2.
miR (show MLXIP Antibodies)-137, induced by its upstream transcription factor HMGA1 (show HMGA1 Antibodies), can suppress colorectal cancer cell invasion and metastasis by targeting FMNL2.
Protein N-myristoylation plays critical roles in the cellular morphological changes induced by FMNL2 and FMNL3 (show FMNL3 Antibodies).
FMNL2 is a novel elongation factor of actin filaments that constitutes the first Cdc42 effector promoting cell migration and actin polymerization at the tips of lamellipodia.
formin-like 2 expression correlated positively with tumor differentiation (P = .046) and vascular invasion (P = .008). Patients whose tumors had lower formin-like 2 expression had shorter overall survival times
FMNL1 (show FMNL1 Antibodies) and FMNL2 are required non-redundantly in the repair of damaged myofibrils.
mDia1-FH2 has an effect on the conformation of actin filaments
This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has yet to be determined.
, formin homology 2 domain containing 2
, formin homology 2 domain-containing protein 2
, formin-like protein 2
, formin-like domain containing protein MAN
, protein Man