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FMNL1 encodes a formin-related protein. Additionally we are shipping Formin-Like 1 Proteins (5) and Formin-Like 1 Kits (2) and many more products for this protein.
Showing 10 out of 34 products:
Human Polyclonal FMNL1 Primary Antibody for ICC, IF - ABIN4312210
Gardberg, Heuser, Iljin, Kampf, Uhlen, Carpén: Characterization of Leukocyte Formin FMNL1 Expression in Human Tissues. in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2014
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FMNL1 contributes to leukemogenesis and could act in part through Rac1 regulation.
constitutively activated form of FMNL1 (FMNL1gamma) induces localization of AHNAK1 (show AHNAK Antibodies) to the cell membrane.
Results suggest that macrophage coiling phagocytosis is a complex process involving several actin nucleation/regulatory factors. They also point specifically to the formins mDia1 and FMNL1 as novel regulators of spirochete uptake by human immune cells.
after Rac-dependent activation of FMNL1, srGAP2 mediates a potent mechanism to limit the duration of Rac action and inhibit formin activity during rapid actin dynamics.
Our data suggest that FRL1 is responsible for modifying actin at the macrophage podosome and may be involved in actin cytoskeleton dynamics during adhesion and migration within tissues.
Results describe N-myristoylation as a regulative mechanism of FMNL1 responsible for membrane trafficking potentially involved in a diversity of polarized processes of hematopoietic lineage-derived cells.
In oocyte meiosis, FMNL1 is required for spindle organization and actin assembly.
Depleting FMNL1, another Formin (show FMN1 Antibodies) family member, resulted in reduced mDia1 expression, while RhoA (show RHOA Antibodies) inhibition did not alter mDia1 expression, which indicated that there was a FMNL1-mDia1-Profilin1 (show PFN1 Antibodies) signaling pathway in mouse oocytes.
FMNL1 and FMNL2 (show FMNL2 Antibodies) are required non-redundantly in the repair of damaged myofibrils.
Binding to interphase microtubules through exon-2-encoded domain of Fmn1 provides a novel mechanism by which Fmn1 isoform Ib could coordinate actin filaments and microtubules.
the bundling activities of FRL1 and mDia2 (show DIAPH3 Antibodies), while producing phenotypically similar bundles, differ in mechanistic detail
A new allele of limb deformity is described due to complete deletion of Fmn1 (show FMN1 Antibodies), including its global control region.
In vitro rheologic assays were used to deconvolve the dynamic cross-linking activity from the bundling activity of formin (show FMN1 Antibodies) FRL1 and the closely related mDia1 and mDia2 (show DIAPH3 Antibodies).
This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. An alternative splice variant has been described but its full length sequence has not been determined.
, formin-like protein 1-like
, CLL-associated antigen KW-13
, formin-like protein 1
, leukocyte formin
, formin-related gene in leukocytes
, formin-related protein
, lymphocyte specific formin related protein