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FPR1 encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. Additionally we are shipping FPR1 Kits (7) and FPR1 Proteins (5) and many more products for this protein.
Showing 10 out of 117 products:
Human Monoclonal FPR1 Primary Antibody for CyTOF, FACS - ABIN4899071
Prevete, Liotti, Visciano, Marone, Melillo, de Paulis: The formyl peptide receptor 1 exerts a tumor suppressor function in human gastric cancer by inhibiting angiogenesis. in Oncogene 2015
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Human Monoclonal FPR1 Primary Antibody for FACS - ABIN4895417
Schneider, Weaver, Gaur, Tripathi, Jesaitis, Zelenka, Gao, Murphy: The leukocyte chemotactic receptor FPR1 is functionally expressed on human lens epithelial cells. in The Journal of biological chemistry 2012
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The data demonstrate that FPR1 is involved in neuroblastoma (show ARHGEF16 Antibodies) development and could represent a therapy option for the treatment of neuroblastoma (show ARHGEF16 Antibodies).
FAM3D plays a role in gastrointestinal homeostasis and inflammation through its receptors FPR1 and FPR2 (show FPR2 Antibodies).
Formylated MHC class Ib (show HLAF Antibodies) binding peptides activate both human and mouse neutrophils primarily through FPR1.
The inhibitory function of oxidant sensing by TRPM2 (show CLU Antibodies) requires the oxidation of Cys549, which then induces TRMP2 binding to formyl peptide receptor 1 (FPR1) and subsequent FPR1 internalization and signaling inhibition
FPR1 expression is significantly upregulated in human masticatory mucosa during wound healing
FAM19A4 (show FAM19A4 Antibodies) is a novel ligand of formyl peptide receptor 1.
The authors describe here the activation of isolated human blood neutrophils by TcdB and, moreover, by toxin fragments generated by limited proteolytical digestion via the FPR1 receptor.
these results highlight the importance of FPR1 in chemotherapy-induced anticancer immune responses.
Data suggest that formyl peptide receptor 1 (FPR1) stimulation may represent a novel therapeutic approach to counteract tumor angiogenesis.
a pepducin designed to target FPR1 was found to hijack FPR2 (show FPR2 Antibodies) and potently inhibit neutrophil functions
Intravital TPLSM revealed that formyl-peptide-FPR1 signaling is responsible for regulating neutrophil chemotaxis to allow migration into the necrotic area in hepatic ischemia-reperfusion injury
Formylated MHC class Ib binding peptides activate both human and mouse neutrophils primarily through FPR1.
Blocking of FPR1 completely abrogated the fMet-Leu-Phe-, gliadin- and synthetic peptide-induced migration.
Ovalbumininduced airway inflammation is mediated by upregulation of the TLR2 (show TLR2 Antibodies)/MyD88 (show MYD88 Antibodies)/NFkappaB signaling pathway and inhibition of LXA4R.
Deficiency of formyl peptide receptor 1 is associated with increased inflammation and enhanced liver injury after LPS (show TLR4 Antibodies)-stimulation
Fpr1/2 are critical for normal healing of the sterile skin wound by mediating the first wave of neutrophil infiltration.
these findings identify a novel role of FPR1 as pattern recognition receptors for perceiving the enteric microbiota that promotes repair of mucosal wounds via generation of reactive oxygen species from the enterocyte NOX1 (show NOX1 Antibodies).
FPR1 and FPR2 (show FPR2 Antibodies) play an important role in the innate immune responses against Streptococcus pneumoniae within the central nervous system and the lack of the receptors leads to a dysregulation of the inflammatory response compared with wild-type mice.
This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.
N-formylpeptide chemoattractant receptor
, fMLP receptor
, fMet-Leu-Phe receptor
, N-formyl peptide receptor
, lipoxin A4 receptor