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Low affinity receptor for N-formyl-methionyl peptides. Additionally we are shipping Formyl Peptide Receptor 2 Antibodies (134) and Formyl Peptide Receptor 2 Kits (45) and many more products for this protein.
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FAM3D plays a role in gastrointestinal homeostasis and inflammation through its receptors FPR1 (show FPR1 Proteins) and FPR2.
Our findings provide evidence for defective LXA4 generation and FPR2/ALXR expression that, associated with increased LTB4 (show PTGR1 Proteins), might be involved in a reduction in the ability of inhaled corticosteroids to impair control of airway inflammation in children with SA.
These data show that viral replication and IAV pathogenesis depend on FPR2 signaling and suggest that FPR2 may be a promising novel strategy to treat influenza.
Changes in the histone acetylation/methylation status enhanced FPR2 signaling in response to LXA4 during inflammation process.
a novel FPR2 agonist, the proteolytically stable alpha-peptide/beta-peptoid hybrid Lau-((S)-Aoc)-(Lys (show LYZ Proteins)-betaNphe)6-NH2 (F2M2), showing comparable potency in activating human and mouse neutrophils by inducing a rise in intracellular Ca(2 (show CA2 Proteins)+) concentration and assembly of the superoxide-generating NADPH oxidase (show NOX1 Proteins).
We conclude that ANX-A1 (show ANXA1 Proteins) is an important regulator of mast cell reactivity to compound 48/80 exerting a negative feedback effect through a mechanism that depends at least partly on the FPR (show FPR1 Proteins) receptor
pro-inflammatory stimuli lead to FPR2/ALX expression while LXA4 induces an anti-inflammatory response
Data show that the purinergic receptor P2Y2 (P2Y2R (show P2RY2 Proteins)) pepducin activates neutrophils through formyl peptide receptor 2 (FPR2), and ATP is turned into an activating agonist through a receptor cross-talk mechanism that involves both FPR2 and P2Y2R (show P2RY2 Proteins).
Serum amyloid A1alpha induces paracrine IL-8/CXCL8 (show IL8 Proteins) via TLR2 and directly synergizes with this chemokine (show CCL1 Proteins) via CXCR2 (show CXCR2 Proteins) and formyl peptide receptor 2 to recruit neutrophils.
a pepducin designed to target FPR1 (show FPR1 Proteins) was found to hijack FPR2 and potently inhibit neutrophil functions
we suggest that Fpr2-mediated signaling in follicular dendritic cells plays a key role in germinal center maintenance in Peyer's patches
ALOX5AP (show ALOX5AP Proteins) Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin (show INS Proteins) Resistance
antagonist pretreatment or gene silencing of the RvD1 receptor, ALX/FPR2, abrogated the anti-inflammatory and pro-resolving actions of RvD1. These data indicate that RvD1 ameliorates IR-induced liver injury, and this protection is associated with enhancement of M2 polarization and efferocytosis via ALX/FPR2 activation
The genome of at least 19 strains encodes a non-functional Fpr3 (show FPR3 Proteins) variant, whereas at least 13 other strains express an intact receptor. These results provide a foundation for understanding the in vivo function of Fpr3 (show FPR3 Proteins).
annexin A1 (show ANXA1 Proteins)- formyl peptide receptor 2 pathway mediated the insulin (show INS Proteins) resistance of skeletal muscle, as well as systemic insulin (show INS Proteins) sensitivity.
Deficiency of formyl peptide receptor 2 is associated with increased inflammation and enhanced liver injury after LPS (show TLR4 Proteins)-stimulation
Low affinity receptor for N-formyl-methionyl peptides. Receptor for lipoxin A4. May have an olfactory function associated with the identification of pathogens or of pathogenic states.
formyl peptide receptor-like 1
, formyl peptide receptor 2
, FMLP-related receptor I
, LXA4 receptor
, N-formyl peptide receptor 2
, lipoxin A4 receptor (formyl peptide receptor related)
, N-formylpeptide receptor-like 2
, formyl peptide receptor, related sequence 2
, formylpeptide receptor-related sequence 2
, lipoxin A4 receptor-like protein
, formyl peptide receptor, related sequence 2-like
, n-formyl peptide receptor 2
, low affinity N-formyl peptide receptor
, N-formyl peptide receptor 3
, N-formylpeptide receptor-like 1
, formyl peptide receptor-related sequence 1
, lipoxin A4 receptor