You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Four and A Half LIM Domains 1 (FHL1) Antibodies

FHL1 encodes a member of the four-and-a-half-LIM-only protein family. Additionally we are shipping Four and A Half LIM Domains 1 Proteins (10) and Four and A Half LIM Domains 1 Kits (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FHL1 2273 Q13642
FHL1 14199 P97447
FHL1 25177 Q9WUH4
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-Four and A Half LIM Domains 1 Antibodies at antibodies-online.com

Showing 10 out of 100 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-FHL1 Antibody Titration: 0.2-1 ug/mlPositive Control: Human brain 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Dog Rabbit Un-conjugated IHC, WB WB Suggested Anti-FHL1  Antibody Titration: 0.1 µg/mL ELISA Titer: 1:.12500  Positive Control: Human Muscle 100 μL Log in to see 2 to 3 Days
$229.00
Details
Cow Goat Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN185289 staining (0.05µg/ml) of Human Muscle lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of FHL1 Antibody (C-term) (ABIN390835) in NIH-3T3 cell line lysates (35 µg/lane). FHL1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human skeletal muscle reacted with FHL1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated ELISA, WB ABIN185290 (0.01µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Mouse Un-conjugated FACS, IF, WB HEK293T cells transfected with either RC203478 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-FHL1 antibody (ABIN2453832), and then analyzed by flow cytometry. Anti-FHL1 mouse monoclonal antibody (ABIN2453832) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY FHL1 (RC203478). 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated ELISA, WB FHL1 monoclonal antibody (M05), clone 2F7. Western Blot analysis of FHL1 expression in PC-12 . Detection limit for recombinant GST tagged FHL1 is approximately 0.3ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details

FHL1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
, ,
,
, , , , ,
Mouse (Murine) ,
,

Rat (Rattus) ,
, ,
,

Top referenced anti-Four and A Half LIM Domains 1 Antibodies

  1. Dog (Canine) Polyclonal FHL1 Primary Antibody for IHC, WB - ABIN2775759 : McGrath, Mitchell, Coghill, Robinson, Brown: Skeletal muscle LIM protein 1 (SLIM1/FHL1) induces alpha 5 beta 1-integrin-dependent myocyte elongation. in American journal of physiology. Cell physiology 2003 (PubMed)
    Show all 9 references for ABIN2775759

  2. Human Polyclonal FHL1 Primary Antibody for IHC, ELISA - ABIN185289 : Brown, McGrath, Ooms, Gurung, Maimone, Mitchell et al.: Characterization of two isoforms of the skeletal muscle LIM protein 1, SLIM1. Localization of SLIM1 at focal adhesions and the isoform slimmer in the nucleus of myoblasts and cytoplasm of myotubes ... in The Journal of biological chemistry 1999 (PubMed)
    Show all 4 references for ABIN185289

  3. Cow (Bovine) Polyclonal FHL1 Primary Antibody for EIA, IHC (p) - ABIN374471 : Tang, Lai, Hammond, Roth, Yang, Guo, Gao: Adenylyl cyclase 6 deletion reduces left ventricular hypertrophy, dilation, dysfunction, and fibrosis in pressure-overloaded female mice. in Journal of the American College of Cardiology 2010 (PubMed)
    Show all 3 references for ABIN374471

  4. Human Monoclonal FHL1 Primary Antibody for ELISA, WB - ABIN515655 : Sakashita, Mimori, Tanaka, Kamohara, Inoue, Sawada, Hirakawa, Mori: Clinical significance of loss of Fhl1 expression in human gastric cancer. in Annals of surgical oncology 2008 (PubMed)

  5. Human Polyclonal FHL1 Primary Antibody for FACS, IHC (p) - ABIN390835 : Gueneau, Bertrand, Jais, Salih, Stojkovic, Wehnert, Hoeltzenbein, Spuler, Saitoh, Verschueren, Tranchant, Beuvin, Lacene, Romero, Heath, Zelenika, Voit, Eymard, Ben Yaou, Bonne: Mutations of the FHL1 gene cause Emery-Dreifuss muscular dystrophy. in American journal of human genetics 2009 (PubMed)

  6. Cow (Bovine) Polyclonal FHL1 Primary Antibody for WB - ABIN2777486 : Rice, Kees, Greene: Transcriptional regulation of FHL1 by TLX1/HOX11 is dosage, cell-type and promoter context-dependent. in Biochemical and biophysical research communications 2008 (PubMed)

More Antibodies against Four and A Half LIM Domains 1 Interaction Partners

Human Four and A Half LIM Domains 1 (FHL1) interaction partners

  1. Knockdown of FHL1 with FHL1 small interfering RNA (siRNA) promoted tumor growth and Cyclin D and cyclin E (show CCNE1 Antibodies) were markedly elevated at both the protein and mRNA level.

  2. results indicate that anti-FHL1 autoantibodies in peripheral blood have promising potential as a biomarker to identify a subset of severe IIM.

  3. In healthy individuals, FHL1A is the predominant splice variant and is mainly found in skeletal and cardiac muscle. In two individuals with an Emery-Dreifuss plus phenotype with pulmonary artery hypoplasia and facial dysmorphology, there was demonstrated loss of isoform A and B, and an almost 200-fold overexpression of isoform C.

  4. FRG1 (show FRG1 Antibodies) mice overexpressing FHL1 showed an improvement in the dystrophic phenotype

  5. FHL1 shRNA could significantly accelerate tumor cell growth via inhibiting the expression of FHL1

  6. Our results suggest that miR (show MLXIP Antibodies)-410 may function as an oncomiR and are consistent with its key function in regulating FHL1 in certain digestive system cancers.

  7. These data suggested that up-regulated FHL1 in smooth muscle in HSCR (show EDNRB Antibodies) might be associated with intestinal wall remodeling in HSCR (show EDNRB Antibodies) and might be one of the risk factors for gastrointestinal motor dysfunction

  8. This is the first study to show that FHL1 mutations identified in several clinically distinct myopathies lead to similar protein aggregation and impair myotube formation.

  9. The study has revealed that FHL1C overexpression induces Jurkat cell apoptosis.

  10. FHL-1 is the predominant complement regulator in Bruch's membrane having direct implications for age-related macular degeneration.

Mouse (Murine) Four and A Half LIM Domains 1 (FHL1) interaction partners

  1. KyoT2 downregulates airway remodeling and resistance in asthmatic mice through a Hes1-dependent mechanism.

  2. Results found that osteogenesis increases with the overexpression of Fhl1 and decreases with reduced Fhl1 expression and suggest that Fhl1 mediates interacting estrogen and Wnt (show WNT2 Antibodies) signaling during osteogenesis.

  3. Findings indicate that loss of function is responsible for the myopathy in the Fhl1 W122S knock-in mice.

  4. The CSL (show SMPX Antibodies)-KyoT2 corepressor complex is a negative regulator of Notch (show NOTCH1 Antibodies) signaling.

  5. Data show that loss of FHL1 function leads to myopathy in vivo and suggest that loss of function of FHL1 may be one of the mechanisms underlying muscle dystrophy in patients with FHL1 mutations.

  6. Fhl1 transcriptional changes provide salutary effects on stressed myocytes in cardiomyopathy.

  7. Data suggest Fhl1 (four-and-a-half LIM domains protein 1) and FHL2 (four-and-a-half LIM domains protein 2 (show FHL2 Antibodies)) bind to and regulate activity of Prkd1 (protein kinase D (show PRKD1 Antibodies) 1) in cardiac/ventricular myocytes; knockdown of Fhl1 down-regulates Prkd1 (show PRKD1 Antibodies) activation.

  8. A novel mechanism involving four-and-a-half LIM domain protein (show PDLIM7 Antibodies)-1 and extracellular signal-regulated kinase-2 (show MAPK1 Antibodies) regulates titin (show TTN Antibodies) phosphorylation and mechanics.

  9. Wnt (show WNT2 Antibodies) signaling induces muscle cell differentiation, at least partly, through Fhl1 activation.

  10. FHL1 is a novel regulator of myosin-binding (show PPP1R12A Antibodies) protein C (show PROC Antibodies) activity that may have a role in sarcomere assembly

Pig (Porcine) Four and A Half LIM Domains 1 (FHL1) interaction partners

  1. The LIM domain protein (show PDLIM7 Antibodies) FHL1C interacts with tight junction protein ZO-1 (show TJP1 Antibodies) contributing to the epithelial-mesenchymal transition of a breast adenocarcinoma cell line.

Four and A Half LIM Domains 1 (FHL1) Antigen Profile

Protein Summary

This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.

Gene names and symbols associated with FHL1

  • four and a half LIM domains 1 (fhl1) antibody
  • four and a half LIM domains 1 (FHL1) antibody
  • four and a half LIM domains 1 (LOC100357263) antibody
  • four and a half LIM domains 1a (fhl1a) antibody
  • Four and a half LIM domains protein 1 (fhl1) antibody
  • four and a half lim domains protein 1 (fhl1) antibody
  • four and a half LIM domains 1 (Fhl1) antibody
  • four and a half LIM domains 1 protein, isoform C (FHL1C) antibody
  • DKFZp468O1927 antibody
  • fhl antibody
  • FHL-1 antibody
  • Fhl1 antibody
  • FHL1A antibody
  • FHL1B antibody
  • fhla antibody
  • FLH1A antibody
  • KyoT antibody
  • MGC89165 antibody
  • SLIM antibody
  • SLIM-1 antibody
  • SLIM1 antibody
  • SLIMMER antibody
  • XMPMA antibody
  • zgc:92025 antibody

Protein level used designations for FHL1

four and a half LIM domains 1 , four and a half LIM domains protein 1-like , four and a half LIM domains a , four and a half LIM domains protein 1 , Four and a half LIM domains protein 1 , four and a half lim domains protein 1 , LIM protein SLIMMER , four-and-a-half Lin11, Isl-1 and Mec-3 domains 1 , skeletal muscle LIM-protein 1 , FHL-1 , RAM14-1 , RBP-associated molecule 14-1 , SLIM , SLIM-1 , four and a half LIM domains 1 protein

GENE ID SPECIES
448334 Xenopus (Silurana) tropicalis
710692 Macaca mulatta
100172515 Pongo abelii
100307044 Ovis aries
100357263 Oryctolagus cuniculus
100387250 Callithrix jacchus
100590327 Nomascus leucogenys
399646 Danio rerio
100196873 Salmo salar
100529032 Ictalurus punctatus
447182 Xenopus laevis
2273 Homo sapiens
14199 Mus musculus
25177 Rattus norvegicus
509056 Bos taurus
397667 Sus scrofa
492162 Canis lupus familiaris
Selected quality suppliers for anti-Four and A Half LIM Domains 1 (FHL1) Antibodies
Did you look for something else?