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anti-Four and A Half LIM Domains 2 (FHL2) Antibodies

The protein encoded by FHL2 is a member of the fibroblast growth factor (FGF) family. Additionally we are shipping Four and A Half LIM Domains 2 Proteins (11) and Four and A Half LIM Domains 2 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FHL2 2274 Q14192
FHL2 14200 O70433
FHL2 63839 O35115
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Top anti-Four and A Half LIM Domains 2 Antibodies at antibodies-online.com

Showing 10 out of 82 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-FHL2  Antibody Titration: 0.6 µg/mL ELISA Titer: 1:.12500  Positive Control: Human heart 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Goat Un-conjugated ELISA, WB ABIN185198 (1µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$326.89
Details
Cow Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: FHL2 Antibody [NBP1-84978] - Staining of human heart muscle shows strong cytoplasmic positivity in myocytes. Western Blot: FHL2 Antibody [NBP1-84978] - Lane 1: Marker [kDa] 229, 112, 84, 48, 32, 27, 17.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp 0.1 mL Log in to see 8 to 11 Days
$439.69
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunofluorescence: FHL2 Antibody [NBP1-84979] - Staining of human cell line U-2 OS shows positivity in cytoskeleton (actin filaments) & focal adhesions. Immunohistochemistry-Paraffin: FHL2 Antibody [NBP1-84979] - Staining of human heart muscle shows strong nuclear and cytoplasmic positivity in myocytes. 0.1 mL Log in to see 8 to 11 Days
$439.69
Details
Human Mouse Un-conjugated IHC (fro), IF, IHC (p), WB   0.1 mg Log in to see 6 to 8 Days
$720.50
Details
Human Mouse Un-conjugated IHC (p), IP, WB 0.1 mg Log in to see 6 to 8 Days
$434.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: FHL2 Antibody [NBP1-33603] - Sample (50 ug of whole cell lysate) A: mouse brain 12% SDS PAGE; antibody diluted at 1:1000. 100 μL Log in to see 5 to 7 Days
$447.56
Details

FHL2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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Mouse (Murine)
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Rat (Rattus)
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Top referenced anti-Four and A Half LIM Domains 2 Antibodies

  1. Human Polyclonal FHL2 Primary Antibody for WB - ABIN265171 : Campo-Fernández, Morandell, Santer, Zwerschke, Jansen-Dürr: Identification of the FHL2 transcriptional coactivator as a new functional target of the E7 oncoprotein of human papillomavirus type 16. in Journal of virology 2006 (PubMed)
    Show all 6 references for ABIN265171

  2. Cow (Bovine) Polyclonal FHL2 Primary Antibody for IHC, WB - ABIN2775839 : Lee, Chung, Kang: Combined treatment of high pressure and heat on killing spores of Alicyclobacillus acidoterrestris in apple juice concentrate. in Journal of food protection 2006 (PubMed)
    Show all 4 references for ABIN2775839

  3. Human Polyclonal FHL2 Primary Antibody for ICC, IF - ABIN4311635 : Pontén, Gry, Fagerberg, Lundberg, Asplund, Berglund, Oksvold, Björling, Hober, Kampf, Navani, Nilsson, Ottosson, Persson, Wernérus, Wester, Uhlén: A global view of protein expression in human cells, tissues, and organs. in Molecular systems biology 2009 (PubMed)
    Show all 3 references for ABIN4311635

  4. Human Polyclonal FHL2 Primary Antibody for ICC, IF - ABIN4311636 : Li, Ponten, dos Remedios: The interactome of LIM domain proteins: the contributions of LIM domain proteins to heart failure and heart development. in Proteomics 2012 (PubMed)
    Show all 3 references for ABIN4311636

  5. Human Monoclonal FHL2 Primary Antibody for IHC (fro), IF - ABIN1107222 : Samson, Smyth, Janetzky, Wendler, Müller, Schüle, von der Mark, von der Mark, Wixler: The LIM-only proteins FHL2 and FHL3 interact with alpha- and beta-subunits of the muscle alpha7beta1 integrin receptor. in The Journal of biological chemistry 2004 (PubMed)
    Show all 2 references for ABIN1107222

  6. Human Polyclonal FHL2 Primary Antibody for ELISA, WB - ABIN185198 : Morgan, Madgwick: Slim defines a novel family of LIM-proteins expressed in skeletal muscle. in Biochemical and biophysical research communications 1996 (PubMed)

More Antibodies against Four and A Half LIM Domains 2 Interaction Partners

Pig (Porcine) Four and A Half LIM Domains 2 (FHL2) interaction partners

  1. Fibroblast growth factor-2 (show FGF2 Antibodies) promotes in vitro heart valve interstitial cell repair through the Akt1 (show AKT1 Antibodies) pathway.

  2. The overlapping relationships of 3'UTR (show UTS2R Antibodies) ends between NUDT6 (show NUDT6 Antibodies) and FGF-2 (show FGF2 Antibodies) genes, were analyzed.

  3. FGF2 (show FGF2 Antibodies) in porcine ovary may be important for the growth of more follicles due to the localisation and concentration difference between stroma and follicle tissue.

  4. By inducing the release of an endothelial elastase, shear stress induces an integrin-dependent release of FGF-2 (show FGF2 Antibodies) from endothelial cells.

  5. qPCR analysis demonstrated an increase in FGF-2 (show FGF2 Antibodies) mRNA levels beginning on day 75 and on day 114 of pregnancy.

  6. FGF2 (show FGF2 Antibodies) activates FGFR (show FGFR2 Antibodies) which then represses the fibroblast activation of valvular interstitial cells.

  7. FGF2 (show FGF2 Antibodies) effectively blocks transforming growth factor-beta1 (TGF-beta1 (show TGFB1 Antibodies))-mediated myofibroblast activation

  8. upregulation of TGFalpha or FGF2 (show FGF2 Antibodies) expression is not a pre-requisite for enhanced testicular growth and increased Sertoli cell proliferation that occurs subsequent to hemicastration in the neonatal boar

Human Four and A Half LIM Domains 2 (FHL2) interaction partners

  1. FHL2 overexpression could enhance the differentiation and mineralization of human dental pulp cells

  2. findings show that mAbp1 (show DBNL Antibodies) and FHL2 are novel binding partners that differentially regulate Rho GTPase (show RACGAP1 Antibodies) signaling and MTLn3 breast cancer cell invasion

  3. These results identify FHL2 as a novel ge (show MAPK1/3 Antibodies)ne associated with asthma severity in human.

  4. FHL2 might interact with Runx2 (show RUNX2 Antibodies) to mediate mesenchymal cell differentiation at the early stages of tooth development and human dental pulp cell differentiation.

  5. FHL2 overexpression could contribute to the growth, proliferation, invasiveness, and metastasis of human tongue squamous cell carcinoma.

  6. KLF8 (show KLF8 Antibodies)-induced FHL2 activation is a novel and critical signaling mechanism underlying human colorectal cancer invasion and metastasis.

  7. Studies indicate that the LIM (show PDLIM5 Antibodies)-only protein FHL2 interactome is functionally involved in the cardiovascular system.

  8. we conclude that FHL2 has both structural and functional protein-protein interactions with b-catenin in the podocyte nucleus and that FHL2 protein inhibition can mitigate Wnt/b-catenin-induced podocytopathy.

  9. Describe the molecular network governing FHL2 expression, and FHL2-linked cancers and the underlying molecular machinery. Review.

  10. Tumoral expression of nuclear cofactor FHL2 is associated with lymphatic metastasis in sporadic but not in hereditary nonpolyposis colorectal cancer-associated colorectal cancer.

Mouse (Murine) Four and A Half LIM Domains 2 (FHL2) interaction partners

  1. loss of Fhl2 leads to an altered immune response to myocardial ischemia, which results in smaller infarcts and better hemodynamic performance up to 21 days after myocardial ischemia reperfusion.

  2. also found that phosphorylation of ERK1/2 (show MAPK1/3 Antibodies) is markedly attenuated in FHL2-KO lung

  3. FHL2 might interact with Runx2 (show RUNX2 Antibodies) to mediate mesenchymal cell differentiation at the early stages of tooth development and human dental pulp cell differentiation.

  4. Overexpression of FHL2 alone had no effect on Erbin (show ERBB2IP Antibodies) expression, but in the presence of MITF (show MITF Antibodies), Erbin (show ERBB2IP Antibodies) expression was decreased.

  5. these data identify a previously unrecognized role for FHL2 in the pathogenesis of pulmonary granulomatous inflammation

  6. we conclude that FHL2 has both structural and functional protein-protein interactions with b-catenin in the podocyte nucleus and that FHL2 protein inhibition can mitigate Wnt/b-catenin-induced podocytopathy.

  7. FHL2 serves as a protective factor and that, rather than promoting the pathology, the upregulation of FHL2 in RA occurs in frame of a regenerative attempt.

  8. FHL2 regulates hematopoietic stem cell functions under transplantation-induced stress conditions.

  9. The LIM (show PDLIM5 Antibodies)-only protein FHL2 reduces vascular lesion formation involving inhibition of proliferation and migration of smooth muscle cells.

  10. a database of genes that are regulated by FHL2 in liver

Four and A Half LIM Domains 2 (FHL2) Antigen Profile

Protein Summary

This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene names and symbols associated with FHL2

  • four and a half LIM domains 2 (FHL2) antibody
  • four and a half LIM domains 2 (fhl2) antibody
  • four and a half LIM domains 2 (LOC100219958) antibody
  • fibroblast growth factor 2 (basic) (FGF2) antibody
  • fibroblast growth factor 2 (basic) (fgf2) antibody
  • fibroblast growth factor 2 (basic) (LOC100227798) antibody
  • four and a half LIM domains 2 (Fhl2) antibody
  • AAG11 antibody
  • BFGF antibody
  • C76204 antibody
  • DRAL antibody
  • FGF-2 antibody
  • fgfb antibody
  • FHL-2 antibody
  • FHL2 antibody
  • HBGF-2 antibody
  • HBGF2 antibody
  • hbgh-2 antibody
  • LOC100227798 antibody
  • SLIM-3 antibody
  • SLIM3 antibody
  • xfgf2 antibody

Protein level used designations for FHL2

four and a half LIM domains 2 , basic fgf , basic fibroblast growth factor , HBGF-2 , fibroblast growth factor 2 , heparin-binding growth factor 2 , prostatropin , fibroblast growth factor 2 (basic) , LIM domain protein DRAL , aging-associated gene 11 , down-regulated in rhabdomyosarcoma LIM protein , four and a half LIM domains protein 2 , skeletal muscle LIM-protein 3 , FHL-2 , SLIM-3 , SLIM 3

GENE ID SPECIES
459469 Pan troglodytes
100145283 Xenopus (Silurana) tropicalis
100219958 Taeniopygia guttata
397643 Sus scrofa
550087 Xenopus (Silurana) tropicalis
574136 Macaca mulatta
619384 Monodelphis domestica
100033955 Equus caballus
100227798 Taeniopygia guttata
2274 Homo sapiens
474544 Canis lupus familiaris
510008 Bos taurus
14200 Mus musculus
63839 Rattus norvegicus
100513532 Sus scrofa
418726 Gallus gallus
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