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anti-Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1) Antibodies

The protein encoded by FXR1 is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. Additionally we are shipping FXR1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FXR1 14359 Q61584
FXR1 8087 P51114
FXR1 361927 Q5XI81
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Top anti-FXR1 Antibodies at antibodies-online.com

Showing 10 out of 88 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-FXR1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysate WB Suggested Anti-FXR1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Dog Goat Un-conjugated WB 20 μg Log in to see 6 to 8 Days
$203.50
Details
Mouse Goat Un-conjugated ELISA, WB ABIN185683 (0.2µg/ml) staining of NIH/3T3 cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Mouse Rabbit Un-conjugated WB FXR1 Antibody (N-term) (ABIN1881357) western blot analysis in mouse liver tissue lysates (35 µg/lane). This demonstrates the FXR1 antibody detected the FXR1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$595.83
Details
Mouse Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$390.50
Details
Dog Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IHC, ELISA, WB The FXR1 Antibody is used in Western blot to detect FXR1 in HepG2 cell lysates. FXR1 staining in human colon carcinoma. Paraffin-embedded human colon carcinoma is stained with FXR1 Antibody used at 1:100 dilution. 0.1 mg Log in to see 2 to 6 Days
$403.70
Details

FXR1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-FXR1 Antibodies

  1. Mouse (Murine) Polyclonal FXR1 Primary Antibody for WB - ABIN1881357 : Coffee, Tessier, Woodruff, Broadie: Fragile X mental retardation protein has a unique, evolutionarily conserved neuronal function not shared with FXR1P or FXR2P. in Disease models & mechanisms 2010 (PubMed)
    Show all 5 references for ABIN1881357

  2. Chicken Polyclonal FXR1 Primary Antibody for WB - ABIN2778725 : Blonden, van t Padje, Severijnen, Destree, Oostra, Willemsen: Two members of the Fxr gene family, Fmr1 and Fxr1, are differentially expressed in Xenopus tropicalis. in The International journal of developmental biology 2005 (PubMed)

  3. Dog (Canine) Polyclonal FXR1 Primary Antibody for WB - ABIN782994 : Coon, Matsunami, Stevens, Miller, Pingree, Camp, Thomas, Krasny, Lainhart, Leppert, McMahon: Evidence for linkage on chromosome 3q25-27 in a large autism extended pedigree. in Human heredity 2006 (PubMed)

More Antibodies against FXR1 Interaction Partners

Mouse (Murine) Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1) interaction partners

  1. FXR1P is a GSK3beta (show GSK3b Antibodies) substrate with a role in regulating mood and emotion processing

  2. Removal of FXR1P from the forebrain of postnatal mice selectively enhances long-term storage of spatial memories, hippocampal late-phase long-term potentiation (L-LTP (show SCP2 Antibodies)), and de novo GluA2 (show GRIA2 Antibodies) synthesis.

  3. FXR1P was highly expressed during hippocampal development and co-localized with ribosomes and mRNAs in the dendrite and at a subset of spines.

  4. FXR1P is required for efficient processing of pre-microR-9 and pre-microR-124 in vitro and forms a complex with Dicer (show DICER1 Antibodies) and pre-miRNAs.

  5. Fxr1 knockout hearts exhibit an up-regulation of desmoplakin (show DSP Antibodies) and talin2 proteins, which is accompanied by severe disruption of desmosome as well as costamere architecture and composition in the heart

  6. Targeting the p38 mitogen-activated protein kinase (show MAPK14 Antibodies) pathway of LPS (show TLR4 Antibodies)-treated cells with small molecule inhibitors can induce FXR1 protein expression.

  7. Four FXR1 isoforms of molecular weight 70, 74, 78, 80 kDa are widely distributed in mouse organs, while in striated (show NSDHL Antibodies) muscles these isoforms are replaced by proteins of 82 and 84 kDa containing an extra pocket of 27 amino acids.

  8. FXR1P operates as a repressor of TNF (show TNF Antibodies) translation

  9. the data clearly demonstrate the importance of FXR1P RBP (show RBP4 Antibodies) in the regulation of a wide spectrum of inflammatory genes and suggest an important role of MAP signalling in the response of macrophages to selected TLR ligands, including CpG.

  10. Fxr1 regulates mammalian circadian behavioral rhythms.

Xenopus laevis Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1) interaction partners

  1. Fxr1 plays a vital role during Xenopus embryogenesis. Knockdown of Fxr1 has highly muscle-specific (show EIF3K Antibodies) effects leading to disruption of MyoD (show MYOD1 Antibodies) expression, inhibition of somite myotomal cell rotation and segmentation, and abnormal dermatome formation.

Human Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1) interaction partners

  1. P97 (show EIF4G2 Antibodies) interacts with 3' UTR (show UTS2R Antibodies)-binding FXR1a-associated microRNPs and with PARN (show PARN Antibodies), which binds mRNA 5' caps (show CAPS Antibodies), forming a specialized complex to translate recruited mRNAs in these altered canonical translation conditions.

  2. An accumulation of 8 SNPs in the fragile gene family (FMR1 (show FMR1 Antibodies), FXR1 and FXR2 (show FXR2 Antibodies))were found associated with autistic traits in a sample of male patients.

  3. FXR1P is a GSK3beta (show GSK3b Antibodies) substrate with a role in regulating mood and emotion processing

  4. The mechanisms by which FXR1 executes its regulatory function by forming a novel complex with two other oncogenes, protein kinase C (show PKC Antibodies), iota and epithelial cell transforming 2, located in the same amplicon via distinct binding mechanisms, were identified.

  5. binding of PKP1 (show PKP1 Antibodies)/3 to FXR1 was RNA independent, and both PKP3 (show PKP3 Antibodies) and FXR1 stabilized PKP2 (show PKP2 Antibodies) mRNA.

  6. Deregulation of Fragile X-related protein 1 by the lipodystrophic lamin A (show LMNA Antibodies) p.R482W mutation elicits a myogenic gene expression program in preadipocytes.

  7. findings showed that FXR1P interacts with BTF (show BCLAF1 Antibodies) in vivo and proved that FXR1P and BTF (show BCLAF1 Antibodies) can co-localize mainly in the cytoplasm around the nucleus

  8. FXR1 and UPF1 (show UPF1 Antibodies) may have a functional role in prostate cancer progression and metastasis.

  9. Our study describes a novel role of FXR1P that has crucial implications for the understanding of its role during myogenesis and muscle development

  10. Data show that the nuclear localization signals of the FXR1 and FXR2 (show FXR2 Antibodies) comprise tandem Tudor domain architectures.

FXR1 Antigen Profile

Protein Summary

The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with FXR1

  • fragile X mental retardation, autosomal homolog 1 (fxr1) antibody
  • fragile X mental retardation, autosomal homolog 1 (FXR1) antibody
  • fragile X mental retardation gene 1, autosomal homolog (Fxr1) antibody
  • fragile X mental retardation, autosomal homolog 1 (fxr1-a) antibody
  • fragile X mental retardation, autosomal homolog 1 (Fxr1) antibody
  • 1110050J02Rik antibody
  • 9530073J07Rik antibody
  • AI851072 antibody
  • FXR1 antibody
  • Fxr1h antibody
  • FXR1P antibody
  • wu:fb16f11 antibody
  • wu:fd18c10 antibody
  • xfxr1 antibody
  • xFxr1p antibody
  • XtFxr1p antibody
  • zgc:66226 antibody

Protein level used designations for FXR1

Fragile X mental retardation syndrome-related protein 1 homolog , fragile X mental retardation syndrome-related protein 1 homolog , fragile X mental retardation syndrome-related protein 1 , fragile X mental retardation, autosomal homolog 1 , fragile X mental retardation-related protein 1 , fragile X mental retardation syndrome-related protein 1-like , fragile X mental retardation gene, autosomal homolog , fragile-X-related protein 1 , mFxr1p , fragile X-related protein , FXR1 , fragile X mental retardation syndrome-related protein 1 homolog A , xFxr1p-A , hFXR1p , fragile X mental retardation gene 1, autosomal homolog

GENE ID SPECIES
594894 Xenopus (Silurana) tropicalis
710170 Macaca mulatta
746398 Pan troglodytes
100066076 Equus caballus
100172974 Pongo abelii
100340080 Oryctolagus cuniculus
100399500 Callithrix jacchus
100595780 Nomascus leucogenys
14359 Mus musculus
100689323 Cricetulus griseus
398050 Xenopus laevis
424968 Gallus gallus
8087 Homo sapiens
478642 Canis lupus familiaris
536793 Bos taurus
361927 Rattus norvegicus
100155866 Sus scrofa
327220 Danio rerio
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