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Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1) ELISA Kits

The protein encoded by FXR1 is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. Additionally we are shipping FXR1 Antibodies (91) and FXR1 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse FXR1 FXR1 14359 Q61584
Anti-Human FXR1 FXR1 8087 P51114
Anti-Rat FXR1 FXR1 361927 Q5XI81
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More ELISA Kits for FXR1 Interaction Partners

Mouse (Murine) Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1) interaction partners

  1. FXR1P is a GSK3beta substrate with a role in regulating mood and emotion processing

  2. Removal of FXR1P from the forebrain of postnatal mice selectively enhances long-term storage of spatial memories, hippocampal late-phase long-term potentiation (L-LTP (show SCP2 ELISA Kits)), and de novo GluA2 (show GRIA2 ELISA Kits) synthesis.

  3. FXR1P was highly expressed during hippocampal development and co-localized with ribosomes and mRNAs in the dendrite and at a subset of spines.

  4. FXR1P is required for efficient processing of pre-microR-9 and pre-microR-124 in vitro and forms a complex with Dicer (show DICER1 ELISA Kits) and pre-miRNAs.

  5. Fxr1 knockout hearts exhibit an up-regulation of desmoplakin (show DSP ELISA Kits) and talin2 proteins, which is accompanied by severe disruption of desmosome as well as costamere architecture and composition in the heart

  6. Targeting the p38 mitogen-activated protein kinase (show MAPK14 ELISA Kits) pathway of LPS (show TLR4 ELISA Kits)-treated cells with small molecule inhibitors can induce FXR1 protein expression.

  7. Four FXR1 isoforms of molecular weight 70, 74, 78, 80 kDa are widely distributed in mouse organs, while in striated (show NSDHL ELISA Kits) muscles these isoforms are replaced by proteins of 82 and 84 kDa containing an extra pocket of 27 amino acids.

  8. FXR1P operates as a repressor of TNF (show TNF ELISA Kits) translation

  9. the data clearly demonstrate the importance of FXR1P RBP (show RBP4 ELISA Kits) in the regulation of a wide spectrum of inflammatory genes and suggest an important role of MAP signalling in the response of macrophages to selected TLR ligands, including CpG.

  10. Fxr1 regulates mammalian circadian behavioral rhythms.

Xenopus laevis Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1) interaction partners

  1. Fxr1 plays a vital role during Xenopus embryogenesis. Knockdown of Fxr1 has highly muscle-specific (show EIF3K ELISA Kits) effects leading to disruption of MyoD (show MYOD1 ELISA Kits) expression, inhibition of somite myotomal cell rotation and segmentation, and abnormal dermatome formation.

Human Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1) interaction partners

  1. P97 (show EIF4G2 ELISA Kits) interacts with 3' UTR (show UTS2R ELISA Kits)-binding FXR1a-associated microRNPs and with PARN (show PARN ELISA Kits), which binds mRNA 5' caps (show CAPS ELISA Kits), forming a specialized complex to translate recruited mRNAs in these altered canonical translation conditions.

  2. An accumulation of 8 SNPs in the fragile gene family (FMR1 (show FMR1 ELISA Kits), FXR1 and FXR2 (show FXR2 ELISA Kits))were found associated with autistic traits in a sample of male patients.

  3. FXR1P is a GSK3beta substrate with a role in regulating mood and emotion processing

  4. The mechanisms by which FXR1 executes its regulatory function by forming a novel complex with two other oncogenes, protein kinase C (show PKC ELISA Kits), iota and epithelial cell transforming 2, located in the same amplicon via distinct binding mechanisms, were identified.

  5. binding of PKP1 (show PKP1 ELISA Kits)/3 to FXR1 was RNA independent, and both PKP3 (show PKP3 ELISA Kits) and FXR1 stabilized PKP2 (show PKP2 ELISA Kits) mRNA.

  6. Deregulation of Fragile X-related protein 1 by the lipodystrophic lamin A (show LMNA ELISA Kits) p.R482W mutation elicits a myogenic gene expression program in preadipocytes.

  7. findings showed that FXR1P interacts with BTF (show BCLAF1 ELISA Kits) in vivo and proved that FXR1P and BTF (show BCLAF1 ELISA Kits) can co-localize mainly in the cytoplasm around the nucleus

  8. FXR1 and UPF1 (show UPF1 ELISA Kits) may have a functional role in prostate cancer progression and metastasis.

  9. Our study describes a novel role of FXR1P that has crucial implications for the understanding of its role during myogenesis and muscle development

  10. Data show that the nuclear localization signals of the FXR1 and FXR2 (show FXR2 ELISA Kits) comprise tandem Tudor domain architectures.

FXR1 Antigen Profile

Antigen Summary

The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with FXR1

  • fragile X mental retardation, autosomal homolog 1 (fxr1) antibody
  • fragile X mental retardation, autosomal homolog 1 (FXR1) antibody
  • fragile X mental retardation gene 1, autosomal homolog (Fxr1) antibody
  • fragile X mental retardation, autosomal homolog 1 (fxr1-a) antibody
  • fragile X mental retardation, autosomal homolog 1 (Fxr1) antibody
  • 1110050J02Rik antibody
  • 9530073J07Rik antibody
  • AI851072 antibody
  • FXR1 antibody
  • Fxr1h antibody
  • FXR1P antibody
  • wu:fb16f11 antibody
  • wu:fd18c10 antibody
  • xfxr1 antibody
  • xFxr1p antibody
  • XtFxr1p antibody
  • zgc:66226 antibody

Protein level used designations for FXR1

Fragile X mental retardation syndrome-related protein 1 homolog , fragile X mental retardation syndrome-related protein 1 homolog , fragile X mental retardation syndrome-related protein 1 , fragile X mental retardation, autosomal homolog 1 , fragile X mental retardation-related protein 1 , fragile X mental retardation syndrome-related protein 1-like , fragile X mental retardation gene, autosomal homolog , fragile-X-related protein 1 , mFxr1p , fragile X-related protein , FXR1 , fragile X mental retardation syndrome-related protein 1 homolog A , xFxr1p-A , hFXR1p , fragile X mental retardation gene 1, autosomal homolog

GENE ID SPECIES
594894 Xenopus (Silurana) tropicalis
710170 Macaca mulatta
746398 Pan troglodytes
100066076 Equus caballus
100172974 Pongo abelii
100340080 Oryctolagus cuniculus
100399500 Callithrix jacchus
100595780 Nomascus leucogenys
14359 Mus musculus
100689323 Cricetulus griseus
398050 Xenopus laevis
424968 Gallus gallus
8087 Homo sapiens
478642 Canis lupus familiaris
536793 Bos taurus
361927 Rattus norvegicus
100155866 Sus scrofa
327220 Danio rerio
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