You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Fragile X Mental Retardation 1 (FMR1) Antibodies

The protein encoded by FMR1 binds RNA and is associated with polysomes. Additionally we are shipping Fragile X Mental Retardation 1 Proteins (6) and Fragile X Mental Retardation 1 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FMR1 2332 Q06787
FMR1 24948 Q80WE1
FMR1 14265  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-Fragile X Mental Retardation 1 Antibodies at antibodies-online.com

Showing 10 out of 157 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of FMR1 Antibody (N-term) in mouse lung tissue l... 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Formalin-fixed and paraffin-embedded human brain tissue reacted with F... Western blot analysis of FMR1 Antibody (N-term) (ABIN390866) in mouse ... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Fruit Fly Mouse Un-conjugated ICC, IF, IP, ELISA, WB 50 μL Log in to see 5 to 6 Days
$429.10
Details
Rat Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IHC, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane... 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IHC, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane... 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane... 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Anti-FMR1 mouse monoclonal antibody (ABIN2455614) immunofluorescent st... HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane... 100 μL Log in to see 2 to 3 Days
$423.50
Details

FMR1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
, , ,
Rat (Rattus) , , , ,
, ,
Mouse (Murine) , , , ,
, ,

Top referenced anti-Fragile X Mental Retardation 1 Antibodies

  1. Fruit Fly (Drosophila melanogaster) Monoclonal FMR1 Primary Antibody for ICC, IF - ABIN108599 : Wan, Dockendorff, Jongens, Dreyfuss: Characterization of dFMR1, a Drosophila melanogaster homolog of the fragile X mental retardation protein. in Molecular and cellular biology 2000 (PubMed)
    Show all 7 references for ABIN108599

  2. Rat (Rattus) Polyclonal FMR1 Primary Antibody for WB - ABIN610747 : Anderson, Teutsch, Dong, Wortis: An essential role for Bruton's [corrected] tyrosine kinase in the regulation of B-cell apoptosis. in Proceedings of the National Academy of Sciences of the United States of America 1996 (PubMed)
    Show all 2 references for ABIN610747

  3. Human Polyclonal FMR1 Primary Antibody for EIA, WB - ABIN452426 : Dölen, Osterweil, Rao, Smith, Auerbach, Chattarji, Bear: Correction of fragile X syndrome in mice. in Neuron 2007 (PubMed)

  4. Human Polyclonal FMR1 Primary Antibody for EIA, WB - ABIN453027 : Yuhas, Walichiewicz, Pan, Zhang, Casillas, Hagerman, Tassone: High-risk fragile x screening in Guatemala: use of a new blood spot polymerase chain reaction technique. in Genetic testing and molecular biomarkers 2009 (PubMed)

More Antibodies against Fragile X Mental Retardation 1 Interaction Partners

Fruit Fly (Drosophila melanogaster) Fragile X Mental Retardation 1 (FMR1) interaction partners

  1. results support a model whereby dFMRP can modulate the neurotoxicity caused by TDP-43 (show TARDBP Antibodies) overexpression

  2. demonstrate that Zfrp8 genetically interacts with Fmr1 and tral (show LSM14A Antibodies) in an antagonistic manner. Zfrp8 and FMRP both control heterochromatin packaging, also in opposite ways

  3. dFmr1 protein is essential for proper cardiac function and establish the fly as a new model for studying the role(s) of FraX proteins in the heart.

  4. Driving expression of FMRpolyG enhanced induction of UPS impairment in cell models, while prevention of RAN translation attenuated UPS impairment in cells and suppressed the genetic interaction with UPS manipulation in Dr (show USP14 Antibodies)osophila

  5. These results show that dfmr1 acts in a neuron type-specific activity-dependent manner for sculpting dendritic arbors during early-use, critical period development of learning and memory circuitry in the Drosophila brain.

  6. upon the stimulation of replication stress, dFMR1 is associated with chromatin in a domain-specific manner, which is essential for its ability to induce the phosphorylation of H2Av (show H2AFV Antibodies).

  7. FMRP inhibits translation by binding directly to the L5 protein on the 80S ribosome.

  8. FMRP negatively regulates HSPG (show SDC2 Antibodies) co-receptors controlling trans-synaptic signaling during synaptogenesis

  9. FMRP and Ataxin-2 (show ATXN2 Antibodies) have roles in long-term olfactory habituation and neuronal translational control

  10. Dfmr1 mutants are less active than wild-type flies and interact with each other less often. Results raise the possibility of defective social expression with preserved receptive abilities.

Human Fragile X Mental Retardation 1 (FMR1) interaction partners

  1. Identified a tripartite correlation between schizophrenia, miR (show MLXIP Antibodies)-9-5p, and FMR1/FXR1 (show FXR1 Antibodies): functional overlaps and differences between FMR1 and its homologues could potentially shed light on both the function of miR (show MLXIP Antibodies)-9-5p and the etiology of schizophrenia.

  2. The correlation of ovarian reserve and serum anti-Mullerian hormone (show AMH Antibodies) levels and FMR1 CGG repeat number in women with <55 CGG repeats

  3. Advancing age, male sex, and lower X activation of the normal FMR1 allele in women carriers were significant in predicting worse postural balance

  4. found no evidence for a pathological increase in GSK3beta (show GSK3b Antibodies) protein levels upon cellular loss of fragile x mental retardation protein

  5. Silencing of the fragile X mental retardation gene results in Autism spectrum disorder.

  6. An accumulation of 8 SNPs in the fragile gene family (FMR1, FXR1 (show FXR1 Antibodies) and FXR2 (show FXR2 Antibodies))were found associated with autistic traits in a sample of male patients.

  7. these data suggest that RAN translation of FMRpolyG ( FMR1)at CGG repeats triggers induction of UPS impairment and alterations in neuronal proteostasis that contribute to pathogenesis in Fragile X-associated tremor ataxia (show USP14 Antibodies) syndrome.

  8. Results suggest the genetic variation associated with FMR1 affects white matter microstructure independently of overall IQ.

  9. transcriptional silencing in fragile X syndrome via DNA methylation (show HELLS Antibodies) and hydroxymethylation

  10. Screening for fragile X syndrome in males from specialized institutions in the northeast region of Brazil identified two unrelated patients with FMR1 mutations.

Zebrafish Fragile X Mental Retardation 1 (FMR1) interaction partners

  1. We identified thousands of clustered RNA editing sites in the zebrafish transcriptome and showed that Fmrp biochemically interacts with the Adar2a protein. The expression levels of the adar (show ADAR Antibodies) genes and Adar2 (show ADARB1 Antibodies) protein increased in fmr1-/- zebrafish

  2. Loss-of-function fmr1 mutants carrying an anti-fmr1 miRNA transgene show abnormal neuronal morphology and connectivity similar to that seen in human fragile X syndrome.

Mouse (Murine) Fragile X Mental Retardation 1 (FMR1) interaction partners

  1. The present demonstration of FMRP and key regulatory targets in the lens identifies a potential for the lens to provide a new research venue.

  2. examine the status of astrocytes and microglia in the cerebellum of Fmr1 mice during development and in adulthood

  3. Dysregulation of fragile X mental retardation protein (show NUFIP2 Antibodies)-metabotropic glutamate receptor 5 (show GRM5 Antibodies) signaling pathway, accompanied with a downregulation of GABA(A) receptor beta3 subunit expression, may contribute to the 'autistic-like' features knockout mice.

  4. found no evidence for a pathological increase in GSK3beta (show GSK3b Antibodies) protein levels upon cellular loss of FMRP, in contrast to what was found in the brain of Fmr1 knockout mice

  5. Overexpressing TRF2 (show TERF2 Antibodies)-S and silencing FMRP promotes mRNA entry to axons and enhances axonal outgrowth and neurotransmitter release from presynaptic terminals.

  6. fmr1 knock-out mice have deficits in motor learning-induced changes in dendritic spine turnover and new dendritic spine clustering, but not the motor learning-induced long-term stabilization of new dendritic spines.

  7. Fmr1 knockout mice had reduced synaptic vesicle unloading of hippocampal neurons and increased vesicle unloading in cerebellar neurons. FMRP plays a role in presynaptic functions.

  8. Findings unveil important roles for FMRP, FXR2P (show FXR2 Antibodies) and GluA1 (show GRIA1 Antibodies) in neuronal development, uncover a regulatory mechanism of GluA1 (show GRIA1 Antibodies), and reveal a functional convergence between fragile X proteins in neuronal development.

  9. These results suggest a role for GABAB receptor in Fmrp regulation and a potential interest of GABAB receptor signaling in Fragile X syndrome improvement.

  10. A set of protein-coding microRNAs were down-regulated in the hippocampus of Fmr1 knock-out mice.

Fragile X Mental Retardation 1 (FMR1) Antigen Profile

Protein Summary

The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.

Gene names and symbols associated with FMR1

  • CG6203 gene product from transcript CG6203-RC (Fmr1) antibody
  • fragile X mental retardation 1 (FMR1) antibody
  • fragile X mental retardation 1 (Fmr1) antibody
  • fragile X mental retardation 1 (fmr1) antibody
  • fragile X mental retardation syndrome 1 (Fmr1) antibody
  • AT24755 antibody
  • BcDNA:GM08679 antibody
  • cg6203 antibody
  • dfmr antibody
  • dfmr1 antibody
  • dFmrp antibody
  • dfxr antibody
  • dfxr1 antibody
  • dFXRP antibody
  • Dmel\\CG6203 antibody
  • dmfr1 antibody
  • EP(3)3517 antibody
  • fmr antibody
  • Fmr-1 antibody
  • fmr1 antibody
  • Fmrp antibody
  • FRAXA antibody
  • FXR antibody
  • POF antibody
  • POF1 antibody
  • zFMR1 antibody

Protein level used designations for FMR1

CG6203-PA , CG6203-PB , CG6203-PC , CG6203-PD , CG6203-PE , CG6203-PF , CG6203-PG , CG6203-PH , CG6203-PI , Fmr1-PA , Fmr1-PB , Fmr1-PC , Fmr1-PD , Fmr1-PE , Fmr1-PF , Fmr1-PG , Fmr1-PH , Fmr1-PI , Fragile-X mental retardation protein , Fragile-X-related , dFmr1 , drosophila fragile X mental retardation protein , fragile X , fragile X mental retardation , fragile X mental retardation 1 , fragile X mental retardation gene , fragile X mental retardation protein , fragile X protein , fragile X related protein , fragile X-related , fragile x related , fragile-X , fragile X mental retardation protein 1 , fragile X mental retardation protein 1 homolog , fragile X mental retardation syndrome 1 homolog , fragile X mental retardation-1 protein , protein FMR-1 , ragile X mental retardation protein , fragile X mental retardation 1 protein , FMRP , mFmr1p

GENE ID SPECIES
37528 Drosophila melanogaster
465894 Pan troglodytes
2332 Homo sapiens
481070 Canis lupus familiaris
24948 Rattus norvegicus
259191 Danio rerio
422395 Gallus gallus
100155078 Sus scrofa
507482 Bos taurus
100172902 Pongo abelii
14265 Mus musculus
Selected quality suppliers for anti-Fragile X Mental Retardation 1 (FMR1) Antibodies
Did you look for something else?