You are viewing an incomplete version of our website. Please click to reload the website as full version.

Fraser Syndrome 1 (FRAS1) ELISA Kits

FRAS1 encodes an extracellular matrix protein that appears to function in the regulation of epidermal-basement membrane adhesion and organogenesis during development. Additionally we are shipping FRAS1 Antibodies (17) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
FRAS1 80144 Q86XX4
Anti-Rat FRAS1 FRAS1 289486  
FRAS1 231470 Q80T14
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top FRAS1 ELISA Kits at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human
96 Tests Log in to see 11 to 13 Days
$875.60
Details
Mouse
96 Tests Log in to see 11 to 13 Days
$875.60
Details

More ELISA Kits for FRAS1 Interaction Partners

Human Fraser Syndrome 1 (FRAS1) interaction partners

  1. In 15 of 590 families, we identified recessive mutations in the genes FRAS1, FREM2 (show FREM2 ELISA Kits), GRIP1 (show NCOA2 ELISA Kits), FREM1 (show FREM1 ELISA Kits), ITGA8, and GREM1 (show GREM1 ELISA Kits), all of which function in the interaction of the ureteric bud and the metanephric mesenchyme.

  2. Analysis of FRAS1 and STRA6 (show STRA6 ELISA Kits) mutations in the same family with eye anomalies.

  3. First case of a family with two patients affected by Fraser syndrome due to a deletion of 64 kb (deletion 4q21.21) and an additional novel frameshift mutation in exon 66 of the FRAS1 gene.

  4. Heterozygous missense mutations in FRAS1 cause non-syndromic congenital abnormalities of the kidney and urinary tract in humans.

  5. Locus FS1 at chromosome 4q21 is associated with Fraser syndrome. Mutation analysis identified five frameshift mutations in FRAS1, which encodes one member of a family of novel proteins related to an extracellular matrix (ECM) protein found in sea urchin.

  6. In this review, recent studies support direct interactions between Fras1 and Frem proteins and shed new light on their role in the regulation of epidermal-basement membrane adhesion and organogenesis during development.

  7. Supramodular nature of GRIP1 (show NCOA2 ELISA Kits) revealed by the structure of its PDZ12 tandem in complex with the carboxhyl tail of Fras1.

  8. 11 new mutations in FRAS1 were identified in families with Fraser syndrome.

Mouse (Murine) Fraser Syndrome 1 (FRAS1) interaction partners

  1. the role of Fras1 in development

  2. Targeted deletion of Fras1 in kidney podocytes circumvented skin blistering, renal agenesis, and early death.

  3. Report Fras1 up-regulation/Frem down-regulation in nephrons from mice with polycystic kidney disease and Frem2 (show FREM2 ELISA Kits) mutations.

  4. The QBRICK (show FREM1 ELISA Kits), together with Fras1, defines the ability of BMs to bind integrin 81 through modulating the BM assembly of nephronectin (show NPNT ELISA Kits), thereby regulating the integrin 81-mediated signals transmitted from the ureteric buds to the metanephric mesenchyme.

  5. Screened DNA from bl/bl mice and identified a premature termination of mouse Fras1. Thus, the bl mouse is a model for Fraser syndrome in humans.

  6. QBRICK/Frem1 (show FREM1 ELISA Kits), Fras1, and Frem2 (show FREM2 ELISA Kits) interactions at the basement membrane have roles in preventing Fraser syndrome-like defects

  7. Taken together, our findings indicate that besides a cooperative function with Fras1 in embryonic basement membranes, Frem1 (show FREM1 ELISA Kits) can also act independently in processes related to epidermal differentiation.

  8. Study reports the immunofluorescence pattern of Frem3 and a comparative analysis of the spatiotemporal localization of all Fras1/Frem proteins during mouse embryonic development.

  9. Fras1 is not only essential as a component of a macromolecular complex for the extracellular stabilization of Frem2 (show FREM2 ELISA Kits) but it is also required for its proper intracellular trafficking and export from embryonic epithelial cells.

  10. The localization pattern of Fras1 and Frem2 (show FREM2 ELISA Kits) was indistinguishable, while both proteins along with Frem3 could be detected even in the absence of Frem1 (show FREM1 ELISA Kits).

FRAS1 Antigen Profile

Antigen Summary

This gene encodes an extracellular matrix protein that appears to function in the regulation of epidermal-basement membrane adhesion and organogenesis during development. Mutations in this gene cause Fraser syndrome, a multisystem malformation that can include craniofacial, urogenital and respiratory system abnormalities. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with Fraser Syndrome 1 (FRAS1) ELISA Kits

  • Fraser syndrome 1 (FRAS1) antibody
  • Fraser syndrome 1 (Fras1) antibody
  • Fraser syndrome 1 homolog (human) (Fras1) antibody
  • bl antibody
  • E130113P14Rik antibody
  • mKIAA1500 antibody

Protein level used designations for Fraser Syndrome 1 (FRAS1) ELISA Kits

extracellular matrix protein FRAS1 , Fraser syndrome 1 protein , blebbed

GENE ID SPECIES
80144 Homo sapiens
289486 Rattus norvegicus
231470 Mus musculus
Selected quality suppliers for FRAS1 (FRAS1) ELISA Kits
Did you look for something else?