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Friend Leukemia Virus Integration 1 Proteins (FLI1)

FLI1 encodes a transcription factor containing an ETS DNA-binding domain. Additionally we are shipping Friend Leukemia Virus Integration 1 Antibodies (127) and Friend Leukemia Virus Integration 1 Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FLI1 2313 Q01543
FLI1 315532  
FLI1 14247 P26323
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Top Friend Leukemia Virus Integration 1 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,268.83
Details
HOST_Escherichia coli (E. coli) Cat Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

FLI1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus)
Mouse (Murine)

More Proteins for Friend Leukemia Virus Integration 1 (FLI1) Interaction Partners

Xenopus laevis Friend Leukemia Virus Integration 1 (FLI1) interaction partners

Human Friend Leukemia Virus Integration 1 (FLI1) interaction partners

  1. FLI1 promoter hypermethylation is associated with Colorectal Cancer.

  2. Concurrent exogenous expression of three transcription factors, GATA1 (show GATA1 Proteins), FLI1 and TAL1 (show TAL1 Proteins), enables large-scale production of megakaryocytes from human pluripotent stem cells.

  3. Identify SP1 (show PSG1 Proteins) and PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins) signaling as modulators of EWS (show EWSR1 Proteins)/FLI1 gene expression in tumor cell lines.

  4. This study for the first time identifies FLI1 as a clinically and functionally important target gene of metastasis, providing a rationale for developing FLI1 inhibitors in the treatment of breast cancer.

  5. SLFN11 has a role as a transcriptional target of EWS (show EWSR1 Proteins)-FLI1 and is a determinant of drug response in Ewing sarcoma

  6. Overexpression of FLI1 and ERG (show ERG Proteins) genes is sufficient to transdifferentiate erythroblasts to megakaryocytes that can produce functional platelets.

  7. Fli1 is epigenetically suppressed and is a potential predisposing factor in the pathogenesis of systemic sclerosis. (Review)

  8. erythrocyte lineage enforces exclusivity through upregulation of EKLF (show KLF1 Proteins) and its lineage-specific cytokine receptor (show EBI3 Proteins) (EpoR (show EPOR Proteins)) while inhibiting both FLI-1 and the receptor TpoR (show MPL Proteins) (also known as MPL (show MPL Proteins)) for the opposing megakaryocyte lineage

  9. Case Report: SMARCB1 (show SMARCB1 Proteins)-deficient vulvar sarcoma expressing ERG (show ERG Proteins) and FLI1.

  10. Mutation in FLI1 is associated with Paris-Trousseau thrombocytopenia.

Mouse (Murine) Friend Leukemia Virus Integration 1 (FLI1) interaction partners

  1. These results provide the first evidences that Fli-1 positively regulates LPS (show TLR4 Proteins)-induced IL-27 (show IL27 Proteins) production in macrophages

  2. protective against nephritis MRL/lpr (show FAS Proteins) mice

  3. Fli1 is epigenetically suppressed and is a potential predisposing factor in the pathogenesis of systemic sclerosis. (Review)

  4. The short nose, otitis media, and hearing impairment in Jacobsen syndrome are likely because of hemizygosity for ETS1 (show ETS1 Proteins) and FLI1.

  5. Simultaneous downregulation of KLF5 (show KLF5 Proteins) and Fli1 is a key feature underlying systemic sclerosis.

  6. bosentan...increased DNA binding of Fli1 and the suppression of type I collagen expression in systemic sclerosis fibroblasts

  7. FLI1 and GATA2 (show GATA2 Proteins) are upstream regulators of SMAD1 (show SMAD1 Proteins) and SMAD5 (show SMAD5 Proteins) expression in endothelial cells.

  8. These results demonstrate that Fli-1 is a novel regulator of the proinflammatory chemokine (show CCL1 Proteins) MCP-1 (show CPT1B Proteins).

  9. Fli-1 directly increases the expression of IL-6 (show IL6 Proteins) via promoter region binding. This represents one possible mechanism for the protective effect of decreased Fli-1 expression in lupus.

  10. reducing FLI1 in lupus decreases the pathogenicity of T cells by decreasing TCR-specific activation and IL-4 (show IL4 Proteins) production in part through the modulation of glycosphingolipid metabolism

Zebrafish Friend Leukemia Virus Integration 1 (FLI1) interaction partners

  1. Fli+ etsrp (show ETV2 Proteins)+ hemato-vascular progenitor cells proliferate at the lateral plate mesoderm during vasculogenesis in zebrafish.

  2. These results showed that young thrombocytes have higher GATA1 (show GATA1 Proteins) promoter activity, while mature thrombocytes have more fli1 gene promoter transcription.

  3. fli1, and etsrp (show ETV2 Proteins), demonstrated that erg (show KCNH2 Proteins) and fli1 act cooperatively and are required for angiogenesis possibly via direct regulation of an endothelial cell junction molecule, VE-cadherin (show CDH5 Proteins)

  4. Interaction between EWSR1 (show EWSR1 Proteins)/FLI1 and EWSR1 (show EWSR1 Proteins) in Ewing sarcoma may induce mitotic defects leading to genomic instability and subsequent malignant transformation.

Friend Leukemia Virus Integration 1 (FLI1) Protein Profile

Protein Summary

This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11\;22)(q24\;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4\;11)(q21\;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with FLI1

  • Friend leukemia virus integration 1 (LOC100338376)
  • Friend leukemia virus integration 1 (FLI1)
  • Friend leukemia virus integration 1 (fli1-b)
  • Friend leukemia virus integration 1 (fli1)
  • Fli-1 proto-oncogene, ETS transcription factor (FLI1)
  • Fli-1 proto-oncogene, ETS transcription factor (fli1-a)
  • Fli-1 proto-oncogene, ETS transcription factor (Fli1)
  • Friend leukemia integration 1 (Fli1)
  • friend leukemia integration 1a (fli1a)
  • cb855 protein
  • EWSR2 protein
  • fli protein
  • Fli-1 protein
  • fli1 protein
  • MGC121593 protein
  • SIC-1 protein
  • Sic1 protein
  • wu:fc45b11 protein
  • Xfli protein
  • Xfli-1 protein
  • Xfli1 protein
  • xlfli protein

Protein level used designations for FLI1

Friend leukemia virus integration 1 , friend leukemia integration 1 transcription factor-like , Friend leukemia integration 1 transcription factor-like , Ewing sarcoma breakpoint region 2 , Friend leukemia integration 1 transcription factor , proto-oncogene Fli-1 , transcription factor ERGB , retroviral integration site protein Fli-1 homolog , retroviral integration site protein Fli-1 , fli-1 proto-oncogene

GENE ID SPECIES
100338376 Oryctolagus cuniculus
100064591 Equus caballus
451659 Pan troglodytes
100020764 Monodelphis domestica
100036985 Xenopus laevis
100124738 Xenopus (Silurana) tropicalis
100411928 Callithrix jacchus
100445127 Pongo abelii
100469052 Ailuropoda melanoleuca
100545965 Meleagris gallopavo
100607271 Nomascus leucogenys
2313 Homo sapiens
399466 Xenopus laevis
315532 Rattus norvegicus
14247 Mus musculus
30619 Danio rerio
419723 Gallus gallus
489286 Canis lupus familiaris
529124 Bos taurus
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