Friend Leukemia Virus Integration 1 Proteins (FLI1)

FLI1 encodes a transcription factor containing an ETS DNA-binding domain. Additionally we are shipping Friend Leukemia Virus Integration 1 Antibodies (165) and Friend Leukemia Virus Integration 1 Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FLI1 2313 Q01543
FLI1 315532  
FLI1 14247 P26323
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Friend Leukemia Virus Integration 1 Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$3,268.83
Details
HOST_Escherichia coli (E. coli) Human T7 tag,His tag   100 μg Log in to see 15 to 18 Days
$614.00
Details
HOST_Escherichia coli (E. coli) Cat Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details

FLI1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,
Rat (Rattus)
Mouse (Murine)

More Proteins for Friend Leukemia Virus Integration 1 (FLI1) Interaction Partners

Xenopus laevis Friend Leukemia Virus Integration 1 (FLI1) interaction partners

Human Friend Leukemia Virus Integration 1 (FLI1) interaction partners

  1. Fusion of short fragments of EWSR1 (show EWSR1 Proteins) to FLI1 is sufficient to recapitulate BAF (show BANF1 Proteins) complex retargeting and EWS (show EWSR1 Proteins)-FLI1 activities; studies thus demonstrate that the physical properties of prion (show PRNP Proteins)-like domains can retarget critical chromatin regulatory complexes to establish and maintain oncogenic gene expression programs.

  2. In American cutaneous leishmaniasis caused by Leishmania braziliensis infection, MMP1 (show MMP1 Proteins) is regulated by factors other than FLI1, and the influence of IL-6 (show IL6 Proteins) on MMP1 (show MMP1 Proteins) was independent of its effect on FLI1.

  3. epithelial Fli1 deficiency might be involved in the systemic autoimmunity and selective organ fibrosis in systemic sclerosis (SSc (show CYP11A1 Proteins)).

  4. Study found consistent DNA hypomethylation at enhancers regulated by the disease-defining EWS (show EWSR1 Proteins)-FLI1 fusion protein, thus establishing epigenomic enhancer reprogramming as a ubiquitous and characteristic feature of Ewing sarcoma.

  5. loss of ERG (show ERG Proteins) and FLI1 might contribute to the pathogenesis of vascular lung complications through the induction of inflammation.

  6. study shows that FLI-1 is expressed variably in different subtypes of NSCLC, and its expression is related to clinicopathologic parameters and poorer prognosis

  7. ERG (show ERG Proteins) (or FLI1 if available) is useful marker for the diagnosis of Phosphaturic mesenchymal tumors.

  8. FLI1 and MMP9 (show MMP9 Proteins) position differently in prostate cancer than in normal tissue and prostate hyperplasia, whereas MMP2 (show MMP2 Proteins) is repositioned in both prostate cancer and hyperplasia.

  9. FLI1 promoter hypermethylation is associated with Colorectal Cancer.

  10. Concurrent exogenous expression of three transcription factors, GATA1 (show GATA1 Proteins), FLI1 and TAL1 (show TAL1 Proteins), enables large-scale production of megakaryocytes from human pluripotent stem cells.

Mouse (Murine) Friend Leukemia Virus Integration 1 (FLI1) interaction partners

  1. loss of ERG (show ERG Proteins) and FLI1 might contribute to the pathogenesis of vascular lung complications through the induction of inflammation.

  2. These results provide the first evidences that Fli-1 positively regulates LPS (show TLR4 Proteins)-induced IL-27 (show IL27 Proteins) production in macrophages

  3. protective against nephritis MRL/lpr (show FAS Proteins) mice

  4. Fli1 is epigenetically suppressed and is a potential predisposing factor in the pathogenesis of systemic sclerosis. (Review)

  5. The short nose, otitis media, and hearing impairment in Jacobsen syndrome are likely because of hemizygosity for ETS1 (show ETS1 Proteins) and FLI1.

  6. Simultaneous downregulation of KLF5 (show KLF5 Proteins) and Fli1 is a key feature underlying systemic sclerosis.

  7. bosentan...increased DNA binding of Fli1 and the suppression of type I collagen expression in systemic sclerosis fibroblasts

  8. FLI1 and GATA2 (show GATA2 Proteins) are upstream regulators of SMAD1 (show SMAD1 Proteins) and SMAD5 (show SMAD5 Proteins) expression in endothelial cells.

  9. These results demonstrate that Fli-1 is a novel regulator of the proinflammatory chemokine (show CCL1 Proteins) MCP-1 (show CPT1B Proteins).

  10. Fli-1 directly increases the expression of IL-6 (show IL6 Proteins) via promoter region binding. This represents one possible mechanism for the protective effect of decreased Fli-1 expression in lupus.

Zebrafish Friend Leukemia Virus Integration 1 (FLI1) interaction partners

  1. mesodermal Wnt3a (show WNT3A Proteins)-mediated signaling via the transcription factor Lef1 (show LEF1 Proteins) positively regulates EC specification (defined by kdrl expression) at the expense of primitive erythrocyte specification (defined by gata1 (show GATA1 Proteins) expression) in zebrafish embryos.

  2. Fli+ etsrp (show ETV2 Proteins)+ hemato-vascular progenitor cells proliferate at the lateral plate mesoderm during vasculogenesis in zebrafish.

  3. These results showed that young thrombocytes have higher GATA1 (show GATA1 Proteins) promoter activity, while mature thrombocytes have more fli1 gene promoter transcription.

  4. fli1, and etsrp (show ETV2 Proteins), demonstrated that erg (show KCNH2 Proteins) and fli1 act cooperatively and are required for angiogenesis possibly via direct regulation of an endothelial cell junction molecule, VE-cadherin (show CDH5 Proteins)

  5. Interaction between EWSR1 (show EWSR1 Proteins)/FLI1 and EWSR1 (show EWSR1 Proteins) in Ewing sarcoma may induce mitotic defects leading to genomic instability and subsequent malignant transformation.

Friend Leukemia Virus Integration 1 (FLI1) Protein Profile

Protein Summary

This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11\;22)(q24\;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4\;11)(q21\;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with FLI1

  • Friend leukemia virus integration 1 (LOC100338376)
  • Friend leukemia virus integration 1 (FLI1)
  • Friend leukemia virus integration 1 (fli1-b)
  • Friend leukemia virus integration 1 (fli1)
  • Fli-1 proto-oncogene, ETS transcription factor (FLI1)
  • Fli-1 proto-oncogene, ETS transcription factor (fli1-a)
  • Fli-1 proto-oncogene, ETS transcription factor (Fli1)
  • Friend leukemia integration 1 (Fli1)
  • friend leukemia integration 1a (fli1a)
  • cb855 protein
  • EWSR2 protein
  • fli protein
  • Fli-1 protein
  • fli1 protein
  • MGC121593 protein
  • SIC-1 protein
  • Sic1 protein
  • wu:fc45b11 protein
  • Xfli protein
  • Xfli-1 protein
  • Xfli1 protein
  • xlfli protein

Protein level used designations for FLI1

Friend leukemia virus integration 1 , friend leukemia integration 1 transcription factor-like , Friend leukemia integration 1 transcription factor-like , Ewing sarcoma breakpoint region 2 , Friend leukemia integration 1 transcription factor , proto-oncogene Fli-1 , transcription factor ERGB , retroviral integration site protein Fli-1 homolog , retroviral integration site protein Fli-1 , fli-1 proto-oncogene

GENE ID SPECIES
100338376 Oryctolagus cuniculus
100064591 Equus caballus
451659 Pan troglodytes
100020764 Monodelphis domestica
100036985 Xenopus laevis
100124738 Xenopus (Silurana) tropicalis
100411928 Callithrix jacchus
100445127 Pongo abelii
100469052 Ailuropoda melanoleuca
100545965 Meleagris gallopavo
100607271 Nomascus leucogenys
2313 Homo sapiens
399466 Xenopus laevis
315532 Rattus norvegicus
14247 Mus musculus
30619 Danio rerio
419723 Gallus gallus
489286 Canis lupus familiaris
529124 Bos taurus
Selected quality suppliers for Friend Leukemia Virus Integration 1 Proteins (FLI1)
Did you look for something else?