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Fucosyltransferase 1 (Galactoside 2-alpha-L-Fucosyltransferase, H Blood Group) Proteins (FUT1)

The protein encoded by FUT1 is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway. Additionally we are shipping FUT1 Antibodies (35) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FUT1 14343  
Rat FUT1 FUT1 81919 Q10980
FUT1 2523 P19526
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Top FUT1 Proteins at antibodies-online.com

Showing 10 out of 16 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Saguinus fuscicollis His tag   1 mg Log in to see 56 to 66 Days
$2,999.33
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,999.33
Details
Yeast Aotus azarae His tag   1 mg Log in to see 56 to 66 Days
$3,001.17
Details
Yeast Ateles belzebuth His tag   1 mg Log in to see 56 to 66 Days
$3,001.17
Details
Yeast Primates His tag   1 mg Log in to see 56 to 66 Days
$3,001.17
Details

FUT1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , , ,
, ,

More Proteins for Fucosyltransferase 1 (Galactoside 2-alpha-L-Fucosyltransferase, H Blood Group) (FUT1) Interaction Partners

Mouse (Murine) Fucosyltransferase 1 (Galactoside 2-alpha-L-Fucosyltransferase, H Blood Group) (FUT1) interaction partners

  1. Fut1 plays an important role in regulating angiogenesis and ICAM-1 (show ICAM1 Proteins) expression in inflammatory arthritis.

  2. We found that Fut1 mRNA and Fut4 (show FUT4 Proteins) mRNA were upregulated, while Fut2 (show FUT2 Proteins) mRNA and Fut9 (show FUT9 Proteins) mRNA were downregulated by androgen in the caput epididymis.

  3. fucosyltransferase (Fut)-deficient (Fut1, Fut2 (show FUT2 Proteins) and Fut4 (show FUT4 Proteins)) mice which lack LeX (show FUT4 Proteins) or LeY antigen are still fertile.

  4. These results indicate that Fut2 (show FUT2 Proteins)-mediated fucosylated epithelial cells (F-ECs) share M cell-related fucosylated molecules but maintain distinctive EC characteristics, Fut1 is, therefore, a reliable marker for M cells.

  5. FUT1 is essential for fucosylation of glycolipid GA1 in the pancreas.

  6. In null mutant mice lacking FUT1, the absence of blood group (show DARC Proteins) H carbohydrate resulted in the delayed maturation of the glomerular layer of the main olfactory bulb.

  7. Vasculogenesis was the most clearly affected by FUT1 expression, suggesting that tumor angiomorphogenesis may depend on E-selectin (show SELE Proteins)-mediated interaction between HCC (show FAM126A Proteins) and endothelial cells, the inhibition of which remarkably retards tumor growth.

Human Fucosyltransferase 1 (Galactoside 2-alpha-L-Fucosyltransferase, H Blood Group) (FUT1) interaction partners

  1. data confirm the hypothesis that the h2 allele is linked to Se(357, 716), and the concurrence of unique FUT1 and FUT2 (show FUT2 Proteins) mutations is geographically specific.

  2. We show that fut1 in RA synovial fibroblasts is important in angiogenesis, leukocyte-synovial fibroblast adhesion, and synovial fibroblast proliferation

  3. Fut1 plays an important role in regulating angiogenesis and ICAM-1 (show ICAM1 Proteins) expression in inflammatory arthritis.

  4. FUT1 mediates c-Jun (show JUN Proteins)-induced cell proliferation in ovarian cancer cells.c-Jun (show JUN Proteins) transcriptionally modulates FUT1 expression in ovarian cancer cells.

  5. Data indicate that single nucleotide polymorphism (SNPS) in the 3'-untranslated region of the fucosyltransferase 1 (FUT1) gene and intron of the syntaxin 1B (STX1B (show STX1B Proteins)) gene were the top hits for Kawasaki disease (KD) susceptibility.

  6. Data indicate that alpha -1,2 fucosyltransferase (FUT1) 682A> G and 547_552delAG mutations do not affect the transcript efficiency, although various mutations have different impact on the enzyme's activity.

  7. Three new alleles in FUT1 and FUT2 (show FUT2 Proteins) genes were identified in the study. The allelic polymorphisms of FUT1 and FUT2 (show FUT2 Proteins) in Tibetans show a population-specific manner.

  8. FUT1-specific fucosidase diminishes the activation of beta1 integrin.

  9. FUT1 mRNA expression in DLD (show DLD Proteins)-1 cells is transcriptionally regulated by Elk-1 (show ELK1 Proteins).

  10. anti-H could accommodate grafts through triggering apoptosis and down-regulating Fut1 expression to reduce ABH (show ALKBH Proteins) antigens

Pig (Porcine) Fucosyltransferase 1 (Galactoside 2-alpha-L-Fucosyltransferase, H Blood Group) (FUT1) interaction partners

  1. Polymorphism of FUT1 and MUC4 (show MUC4 Proteins) associated with resistance to colibacteriosis was determined.

  2. The 5'-flanking region of the FUT1 gene (-1150 to +50 bp) exhibited promoter activity and the -1150-bp to -849-bp region showed negative regulation of the gene.

  3. Studied the beneficial effects of alpha (1,2)-fucosyltransferase (FUT1) M307 (A) on piglet survival on commercial farms. Piglet survival for individuals with the AA genotype was almost two-fold greater than for GG individuals.

  4. The results indicated that Sutai pigs with the AA genotype in M307 of FUT1 gene have relatively strong general disease resistance ability in piglets.

  5. The mutation at M307 in the FUT1 gene determines susceptibility of small intestinal epithelium to E. coli F18 (show MAMLD1 Proteins) adhesion in Sutai piglets.

  6. FUT1 mutations might play a role in pig infection by multi-pathogens, and the AA may be a favourable genotype for increasing the resistance to disease.

  7. Beneficial genotype of swine FUT1 gene governing resistance to E. coli F18 (show MAMLD1 Proteins) is associated with important economic traits

  8. transgenic male pigs were produced that possess an alpha alpha-1,3-galactosyltransferase (show GGTA1 Proteins) knockout allele and express a randomly inserted human alpha 1,2-fucosylosyltransferase transgene

  9. Results showed that the genetic polymorphisms of the FUT1 locus were only detected in the 3 exotic pig breeds and indicated that FUT 1 gene and the type of breeds significantly affected total number born.

  10. Results indicated that Chinese native pig breeds lack the genetic background, FUT1 genetic polymorphisms, on the resistance to ETEC F18 (show MAMLD1 Proteins) bacteria.

Cow (Bovine) Fucosyltransferase 1 (Galactoside 2-alpha-L-Fucosyltransferase, H Blood Group) (FUT1) interaction partners

  1. Data show that si-RNA induced down-regulation of FUT1 and FUT2 (show FUT2 Proteins) reduced expression of fucosylated nucleolin (show NCL Proteins) glycoforms and their exposure at the cell surface.

FUT1 Protein Profile

Protein Summary

The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway. This gene is one of two encoding the galactoside 2-L-fucosyltransferase enzyme. Mutations in this gene are a cause of the H-Bombay blood group.

Gene names and symbols associated with FUT1

  • fucosyltransferase 1 (Fut1)
  • fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) (FUT1)
  • galactoside 2-L-fucosyltransferase (RFT-I)
  • Fut1 protein
  • Futa protein
  • H protein
  • HH protein
  • HSC protein

Protein level used designations for FUT1

GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1 , H transferase , alpha(1,2)FT 1 , beta-galactoside alpha-1,2-fucosyltransferase , galactoside 2-alpha-L-fucosyltransferase 1 , alpha 1,2-fucosyltransferase A , alpha 12-fucosyltransferase , alpha12-fucosyltransferase a , fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase) , 2-alpha-L-fucosyltransferase , alpha (1,2) fucosyltransferase , blood group H alpha 2-fucosyltransferase , alpha-1,2-fucosyltransferase , alpha(1-2) fucosyltransferase 1 , fucosyltransferase 1

GENE ID SPECIES
14343 Mus musculus
81919 Rattus norvegicus
2523 Homo sapiens
397138 Sus scrofa
281174 Bos taurus
468947 Pan troglodytes
100009291 Oryctolagus cuniculus
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