Fucosyltransferase 1 (Galactoside 2-alpha-L-Fucosyltransferase, H Blood Group) Proteins (FUT1)

The protein encoded by FUT1 is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway. Additionally we are shipping FUT1 Antibodies (36) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FUT1 14343  
Rat FUT1 FUT1 81919 Q10980
FUT1 2523 P19526
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Top FUT1 Proteins at antibodies-online.com

Showing 10 out of 16 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,244.78
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Yeast Wild boar His tag   1 mg Log in to see 60 to 71 Days
$2,999.33
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Yeast Saguinus fuscicollis His tag   1 mg Log in to see 60 to 71 Days
$2,999.33
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Yeast REACT_Woolly monkey His tag   1 mg Log in to see 60 to 71 Days
$3,001.17
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Yeast REACT_Howler monkey His tag   1 mg Log in to see 60 to 71 Days
$3,001.17
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Yeast Primates His tag   1 mg Log in to see 60 to 71 Days
$3,001.17
Details
Yeast Primate His tag   1 mg Log in to see 60 to 71 Days
$3,001.17
Details

FUT1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)
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Human , ,
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More Proteins for Fucosyltransferase 1 (Galactoside 2-alpha-L-Fucosyltransferase, H Blood Group) (FUT1) Interaction Partners

Mouse (Murine) Fucosyltransferase 1 (Galactoside 2-alpha-L-Fucosyltransferase, H Blood Group) (FUT1) interaction partners

  1. Fut1 plays an important role in regulating angiogenesis and ICAM-1 (show ICAM1 Proteins) expression in inflammatory arthritis.

  2. We found that Fut1 mRNA and Fut4 (show FUT4 Proteins) mRNA were upregulated, while Fut2 (show FUT2 Proteins) mRNA and Fut9 (show FUT9 Proteins) mRNA were downregulated by androgen in the caput epididymis.

  3. fucosyltransferase (Fut)-deficient (Fut1, Fut2 (show FUT2 Proteins) and Fut4 (show FUT4 Proteins)) mice which lack LeX (show FUT4 Proteins) or LeY antigen are still fertile.

  4. These results indicate that Fut2 (show FUT2 Proteins)-mediated fucosylated epithelial cells (F-ECs) share M cell-related fucosylated molecules but maintain distinctive EC characteristics, Fut1 is, therefore, a reliable marker for M cells.

  5. FUT1 is essential for fucosylation of glycolipid GA1 in the pancreas.

  6. In null mutant mice lacking FUT1, the absence of blood group (show DARC Proteins) H carbohydrate resulted in the delayed maturation of the glomerular layer of the main olfactory bulb.

  7. Vasculogenesis was the most clearly affected by FUT1 expression, suggesting that tumor angiomorphogenesis may depend on E-selectin (show SELE Proteins)-mediated interaction between HCC (show FAM126A Proteins) and endothelial cells, the inhibition of which remarkably retards tumor growth.

Human Fucosyltransferase 1 (Galactoside 2-alpha-L-Fucosyltransferase, H Blood Group) (FUT1) interaction partners

  1. downregulation of FUT1, which leads to the perinuclear localization of LAMP-1 (show LAMP1 Proteins) and 2, is correlated with increased rate of autophagic flux by decreasing mTOR (show FRAP1 Proteins) signaling and increasing autolysosome formation.

  2. The H blood group (show DARC Proteins) system is defined by a terminal fucose residue found on red blood cells and in secretions formed by the action of alpha-1,2-fucosyltransferases 1 (alpha2FucT1) and 2 (alpha2FucT2), respectively. Mutant alleles of the corresponding FUT1 and FUT2 (show FUT2 Proteins) genes result in either a H- phenotype (Bombay phenotype) or a weak H phenotype (para-Bombay). Review.

  3. Two novel FUT1 mutations have been identified in the proband's FUT1 gene. The insertion mutation in the FUT1 that caused a shift of the open reading frame and formed a termination codon early at Amino Acid Position 334 may be the main reason for H deficiency in this case.

  4. Protein O-fucosyltransferase 1 (show POFUT1 Proteins) promotes trophoblast cell proliferation by activating MAPK (show MAPK1 Proteins) and PI3K (show PIK3CA Proteins)/Akt (show AKT1 Proteins) signaling pathways.[poFUT1 (show POFUT1 Proteins)]

  5. Data suggest that the identification of genes in response to alpha1,2-fucosyl transferase (FUT1) may provide a theoretical basis for the investigations of the molecular mechanism of ovarian cancer.

  6. alpha(1,2)-fucosyltransferase activity is involved in the development of multidrug resistance of chronic myeloid leukemia (show BCL11A Proteins) cells probably through FUT1 regulated the activity of EGFR (show EGFR Proteins)/MAPK (show MAPK1 Proteins) signaling pathway and the expression of P-gp (show ABCB4 Proteins).

  7. data confirm the hypothesis that the h2 allele is linked to Se(357, 716), and the concurrence of unique FUT1 and FUT2 (show FUT2 Proteins) mutations is geographically specific.

  8. We show that fut1 in RA synovial fibroblasts is important in angiogenesis, leukocyte-synovial fibroblast adhesion, and synovial fibroblast proliferation

  9. Fut1 plays an important role in regulating angiogenesis and ICAM-1 (show ICAM1 Proteins) expression in inflammatory arthritis.

  10. FUT1 mediates c-Jun (show JUN Proteins)-induced cell proliferation in ovarian cancer cells.c-Jun (show JUN Proteins) transcriptionally modulates FUT1 expression in ovarian cancer cells.

Pig (Porcine) Fucosyltransferase 1 (Galactoside 2-alpha-L-Fucosyltransferase, H Blood Group) (FUT1) interaction partners

  1. FUT1 expression levels and low FUT2 (show FUT2 Proteins) expression levels in the intestines of Sutai pigs affected FUT1 and FUT2 (show FUT2 Proteins) enzymes, the synthesis of type 2 H and type 1 H antigens, and E. coli F18 (show MAMLD1 Proteins) adhesion. Moreover, low FUT2 (show FUT2 Proteins) expression levels conferred resistance to E. coli F18 (show MAMLD1 Proteins).

  2. Polymorphism of FUT1 and MUC4 (show MUC4 Proteins) associated with resistance to colibacteriosis was determined.

  3. The 5'-flanking region of the FUT1 gene (-1150 to +50 bp) exhibited promoter activity and the -1150-bp to -849-bp region showed negative regulation of the gene.

  4. Studied the beneficial effects of alpha (1,2)-fucosyltransferase (FUT1) M307 (A) on piglet survival on commercial farms. Piglet survival for individuals with the AA genotype was almost two-fold greater than for GG individuals.

  5. The results indicated that Sutai pigs with the AA genotype in M307 of FUT1 gene have relatively strong general disease resistance ability in piglets.

  6. The mutation at M307 in the FUT1 gene determines susceptibility of small intestinal epithelium to E. coli F18 (show MAMLD1 Proteins) adhesion in Sutai piglets.

  7. FUT1 mutations might play a role in pig infection by multi-pathogens, and the AA may be a favourable genotype for increasing the resistance to disease.

  8. Beneficial genotype of swine FUT1 gene governing resistance to E. coli F18 (show MAMLD1 Proteins) is associated with important economic traits

  9. transgenic male pigs were produced that possess an alpha alpha-1,3-galactosyltransferase (show GGTA1 Proteins) knockout allele and express a randomly inserted human alpha 1,2-fucosylosyltransferase transgene

  10. Results showed that the genetic polymorphisms of the FUT1 locus were only detected in the 3 exotic pig breeds and indicated that FUT 1 gene and the type of breeds significantly affected total number born.

Cow (Bovine) Fucosyltransferase 1 (Galactoside 2-alpha-L-Fucosyltransferase, H Blood Group) (FUT1) interaction partners

  1. Data show that si-RNA induced down-regulation of FUT1 and FUT2 (show FUT2 Proteins) reduced expression of fucosylated nucleolin (show NCL Proteins) glycoforms and their exposure at the cell surface.

FUT1 Protein Profile

Protein Summary

The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway. This gene is one of two encoding the galactoside 2-L-fucosyltransferase enzyme. Mutations in this gene are a cause of the H-Bombay blood group.

Gene names and symbols associated with FUT1

  • fucosyltransferase 1 (Fut1)
  • fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) (FUT1)
  • galactoside 2-L-fucosyltransferase (RFT-I)
  • Fut1 protein
  • Futa protein
  • H protein
  • HH protein
  • HSC protein

Protein level used designations for FUT1

GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1 , H transferase , alpha(1,2)FT 1 , beta-galactoside alpha-1,2-fucosyltransferase , galactoside 2-alpha-L-fucosyltransferase 1 , alpha 1,2-fucosyltransferase A , alpha 12-fucosyltransferase , alpha12-fucosyltransferase a , fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase) , 2-alpha-L-fucosyltransferase , alpha (1,2) fucosyltransferase , blood group H alpha 2-fucosyltransferase , alpha-1,2-fucosyltransferase , alpha(1-2) fucosyltransferase 1 , fucosyltransferase 1

GENE ID SPECIES
14343 Mus musculus
81919 Rattus norvegicus
2523 Homo sapiens
397138 Sus scrofa
281174 Bos taurus
468947 Pan troglodytes
100009291 Oryctolagus cuniculus
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