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Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) Proteins (FUT3)

The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. Additionally we are shipping FUT3 Antibodies (52) and FUT3 Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FUT3 2525 P21217
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Top FUT3 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$388.93
Details

FUT3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,

More Proteins for Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3) Interaction Partners

Human Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3) interaction partners

  1. Polymorphisms in FUT3 and its intestinal expression might be associated with ulcerative colitis pathogenesis.

  2. Data suggest that fucosyltransferase 3 (FUT3) gene rs28362459 and rs3745635 single nucleotide polymorphisms (SNPs) may engender the increased risk of ileocolonic and ileal Crohn's disease (CD).

  3. Mutations of FUT3 (rs28362459) and (rs3745635) might influence the lesion locations in CD patients.

  4. Use of FUT2 (show FUT2 Proteins)/3 genotype-dependent cut-off values for CA19-9 improved sensitivity and reduced the number of false positive results

  5. Obtained FST (show FST Proteins) values reveal distinct frequencies of the FUT3 SNPs between the present sample and its representative ancestral populations.

  6. down-regulation of FUT3 and FUT5 reduces the expression of sialyl-Lewis antigens and the adhesion capacities of gastric cancer cells and allows to identify the specific alpha1-3,4 fucosyltransferases implicated in the Lewis antigens synthesis

  7. Elevated expression of Topo-I (show TOP1 Proteins) and Topo-II beta (show TOP2B Proteins) is found in Lewis(y) antigen-overexpressing ovarian cancer cells.

  8. LeY is carried by integrin alphavbeta3 and plays a critical role in attachment to cultured cells. LeY activates integrin alphavbeta3/focal adhesion kinase (FAK) signaling.

  9. At physiological levels of wall shear stress, the number of flowing cancer cells recruited to the microtube surface was dramatically reduced by FUT3 knockdown

  10. GALNT14 (show GALNT14 Proteins) and FUT3/6 H-scores were significantly higher in non-small cell lung cancer cell lines sensitive to dulanermin and drozitumab versus resistant cell lines

FUT3 Protein Profile

Protein Summary

The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.

Gene names and symbols associated with FUT3

  • fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) (fut3)
  • fucosyltransferase 5 (alpha (1,3) fucosyltransferase) (FUT5)
  • fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) (FUT3)
  • fucosyltransferase 3 (FUT3)
  • ATFUT3 protein
  • CD174 protein
  • F1M20.10 protein
  • F1M20_10 protein
  • FT3B protein
  • fucosyltransferase 3 protein
  • FucT-III protein
  • FUT protein
  • FUT3 protein
  • fut356 protein
  • FUTB protein
  • LE protein
  • Les protein

Protein level used designations for FUT3

fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) , FUT Lewis , alpha 1,3/4 fucosyltransferase Lewis 2 , alpha (1,3) fucosyltransferase , fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group included) , alpha3-fucosyltransferase , alpha 1,3/4 fucosyltransferase Lewis 1 , alpha-1,3-fucosyltransferase , Lewis FT , alpha-(1,3/1,4)-fucosyltransferase , blood group Lewis alpha-4-fucosyltransferase , fucosyltransferase III , galactoside 3(4)-L-fucosyltransferase , alpha-3/4-fucosyltransferase , fucT-III , fucosyltransferase 5 , lewis FT , alpha 1,3 fucosyltransferase

GENE ID SPECIES
399050 Xenopus laevis
428341 Gallus gallus
447987 Xenopus (Silurana) tropicalis
449025 Sus scrofa
697452 Macaca mulatta
697582 Macaca mulatta
843783 Arabidopsis thaliana
2525 Homo sapiens
493975 Pan troglodytes
338077 Bos taurus
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