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The protein encoded by FUT6 is a Golgi stack membrane protein that is involved in the creation of sialyl-Lewis X, an E-selectin ligand. Additionally we are shipping Fucosyltransferase 6 (Alpha (1,3) Fucosyltransferase) Kits (16) and Fucosyltransferase 6 (Alpha (1,3) Fucosyltransferase) Proteins (3) and many more products for this protein.
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Human Polyclonal FUT6 Primary Antibody for EIA, IHC (p) - ABIN952400
Stern, Padilla, Wagner, Amler, Ashkenazi: Development of immunohistochemistry assays to assess GALNT14 and FUT3/6 in clinical trials of dulanermin and drozitumab. in Clinical cancer research : an official journal of the American Association for Cancer Research 2010
Show all 5 references for ABIN952400
Chicken Polyclonal FUT6 Primary Antibody for WB - ABIN2783381
Higai, Miyazaki, Azuma, Matsumoto: Transcriptional regulation of the fucosyltransferase VI gene in hepatocellular carcinoma cells. in Glycoconjugate journal 2008
characterisation of FUT4 and FUT6 alpha-(1 --> 2)-fucosyltransferases
FUT6 contributed to fucosylation of root arabinogalactan-proteins.
AtFUT4 and AtFUT6 are the first enzymes to be characterized for AGP glycosylation
The T allele of rs3760776 might repress the transcription of the FUT6 gene.
In normal colon samples a significant relationship between sLe(x) expression and the ratio between FUT6/B4GALNT2 (show B4GALNT2 Antibodies) activities exists, demonstrating for the first time a role for B4GALNT2 (show B4GALNT2 Antibodies) in sLe(x) inhibition in vivo
Results suggest that FUT4 (show FUT4 Antibodies)-, FUT6- or FUT8 (show FUT8 Antibodies)-mediated MDR in human HCC (show FAM126A Antibodies) is associated with the activation of the PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) pathway and the expression of MRP1 (show MDM4 Antibodies).
these results suggest that FUT6 plays an important role in hepatocellular carcinoma growth by regulating the PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) signaling pathway.
The biosynthesis of the selectin-ligand sialyl Lewis x (show FUT4 Antibodies) in colorectal cancer tissues is regulated by fucosyltransferase VI and can be inhibited by an RNA interference-based approach.
GALNT14 (show GALNT14 Antibodies) and FUT3 (show FUT3 Antibodies)/6 H-scores were significantly higher in non-small cell lung cancer cell lines sensitive to dulanermin and drozitumab versus resistant cell lines
endo-beta-galactosidase (show GLB1 Antibodies)-sensitive and mAb FH6-reactive carbohydrate chains are generated under the control of expression levels of FUT6 and involved in the adhesion of colon carcinoma cells to liver sections.
5'UT-exons A or C have higher expression of FUT8 (show FUT8 Antibodies) transcripts and higher alpha6-fucosyltransferase activity
IL-1 beta (show IL1B Antibodies)-induced sLeX expression on HuH-7 cells was suppressed by transfection of gene-specific small interference RNAs against FUT VI and ST3Gal IV (show ST3GAL4 Antibodies) but not against FUT IV and ST3Gal III (show ST3GAL3 Antibodies).
results suggested that PKR (show PKLR Antibodies) is the primary target for HSV-1 early RNA during induction of FUT3 (show FUT3 Antibodies), FUT5 (show FUT5 Antibodies), and FUT6
The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of sialyl-Lewis X, an E-selectin ligand. Mutations in this gene are a cause of fucosyltransferase-6 deficiency. Two transcript variants encoding the same protein have been found for this gene.
, fucosyltransferase 5
, fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
, fucosyltransferase VI
, galactoside 3-L-fucosyltransferase