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anti-Fucosyltransferase 8 (Alpha (1,6) Fucosyltransferase) (FUT8) Antibodies

FUT8 encodes an enzyme belonging to the family of fucosyltransferases. Additionally we are shipping FUT8 Kits (18) and FUT8 Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FUT8 53618 Q9WTS2
FUT8 2530 Q9BYC5
FUT8 432392 Q6EV76
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Top anti-FUT8 Antibodies at antibodies-online.com

Showing 10 out of 54 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue reacted with FUT8 Antibody (Center) followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of FUT8 Antibody (Center) in MDA-MB231 cell line lysates (35ug/lane). This demonstrates the FUT8 antibody detected the FUT8 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human cervical carcinoma labeled with Anti FUT8 Polyclonal Antibody, Unconjugated (ABIN716801) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-FUT8 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$527.15
Details
Human Rabbit Un-conjugated IHC (p), WB FUT8 Antibody (Center) (ABIN655075) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Biotin IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit FITC IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

FUT8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against FUT8 Interaction Partners

Mouse (Murine) Fucosyltransferase 8 (Alpha (1,6) Fucosyltransferase) (FUT8) interaction partners

  1. our study provides the first direct evidence for the involvement of Fut8 in liver regeneration.

  2. Loss of core fucosylation on AMPARs enhanced their heteromerization, which increase sensitivity for postsynaptic depolarization and persistently activate N-methyl-d-aspartate receptors as well as Ca(2 (show CA2 Antibodies)+) influx and CaMKII (show CAMK2G Antibodies) and then impair LTP (show SCP2 Antibodies).

  3. findings define FUT8 as a novel factor for hemoglobin production and demonstrate that core fucosylation plays an important role in erythroid differentiation

  4. FUT8 is up-regulated during epithelial-mesenchymal transition (EMT (show ITK Antibodies)), a critical process for malignant transformation of tumor, via the transactivation of beta-catenin (show CTNNB1 Antibodies)/lymphoid enhancer-binding factor-1 (LEF-1 (show LEF1 Antibodies)).

  5. These data suggest that reduced Fut8 activity is associated with the progression of COPD (show ARCN1 Antibodies) and serum Fut8 activity is a non-invasive predictive biomarker candidate for progression and exacerbation of COPD (show ARCN1 Antibodies).

  6. Increased expression and activity of alpha-1,6-fucosyltransferase (FUT8) in the liver are strongly linked to the age-related changes in protein glycosylation.

  7. epidermal growth factor (show EGF Antibodies) induced phosphorylation levels of the EGF receptor (EGFR (show EGFR Antibodies)) were substantially blocked in Fut8-/- cells. Consistent with this, EGFR (show EGFR Antibodies)-mediated JNK (show MAPK8 Antibodies) or ERK (show EPHB2 Antibodies) activation was significantly suppressed in Fut8-/- cells.

  8. EGFR (show EGFR Antibodies)-trypsin-PAR-2 (show F2RL1 Antibodies) pathway is suppressed in Fut8-/- mice.

  9. Reduced alpha4 1 integrin/vascular cell adhesion molecule 1 (show VCAM1 Antibodies) interactions lead to impaired pre-B cell repopulation in alpha 1,6-fucosyltransferase deficient mice

  10. Vascular endothelial growth factor receptor-2 (VEGFR-2 (show KDR Antibodies)) expression was significantly suppressed in Fut8(-/-) mice, suggesting that Fut8 was required for VEGFR-2 (show KDR Antibodies) expression.

Human Fucosyltransferase 8 (Alpha (1,6) Fucosyltransferase) (FUT8) interaction partners

  1. MiR (show MLXIP Antibodies)-198 was shown to target the 3'UTR (show UTS2R Antibodies) of FUT8 directly to downregulate FUT8 expression.

  2. High expression of FUT8 is associated with an unfavorable clinical outcome in patients with potentially curatively resected NSCLCs, suggesting that FUT8 can be a prognostic factor.

  3. Our results suggest that FUT8 may be associated with aggressive PCa (show FLVCR1 Antibodies) and thus is potentially useful for its prognosis.

  4. miR (show MLXIP Antibodies)-122 and miR (show MLXIP Antibodies)-34a are able to target FUT8 3'UTR (show UTS2R Antibodies)

  5. Results suggest that FUT4 (show FUT4 Antibodies)-, FUT6 (show FUT6 Antibodies)- or FUT8-mediated MDR in human HCC (show FAM126A Antibodies) is associated with the activation of the PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) pathway and the expression of MRP1 (show MDM4 Antibodies).

  6. alpha 1,6-fucosyltransferase 8 expression might be a good indicator of poor prognosis in hepatocellular carcinoma. High alpha 1,6-fucosyltransferase 8 expression may play an important role in hepatitis B virus-related hepatocellular carcinoma progression

  7. findings define FUT8 as a novel factor for hemoglobin production and demonstrate that core fucosylation plays an important role in erythroid differentiation

  8. The FUT8 gene Thr267Lys polymorphism is associated with human pulmonary emphysema (PE).

  9. in colorectal carcinoma patients with moderate or strong alpha(1,6)fucosyltransferase expression, a significant decrease in the overall (P = .04) and disease-free (P = .03) survival rates was observed

  10. Expression of FUT8 is regulated by three different promoters, starting transcription in exons A, B, or C.

FUT8 Antigen Profile

Protein Summary

This gene encodes an enzyme belonging to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with FUT8

  • fucosyltransferase 8 (alpha (1,6) fucosyltransferase) (FUT8) antibody
  • fucosyltransferase 8 (Fut8) antibody
  • fucosyltransferase 8 (alpha (1,6) fucosyltransferase) (Fut8) antibody

Protein level used designations for FUT8

GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase , GDP-fucose--glycoprotein fucosyltransferase , alpha (1,6) fucosyltransferase , alpha-(1,6)-fucosyltransferase , alpha-1,6-fucosyltransferase , alpha1-6FucT , glycoprotein 6-alpha-L-fucosyltransferase , N-acetyl-beta-D-glucosaminidealpha-1,6-fucosyltransferase , Glycoprotein 6-alpha-L-fucosyltransferase , alpha 1,6 fucosyltransferase

GENE ID SPECIES
100052546 Equus caballus
53618 Mus musculus
2530 Homo sapiens
396933 Sus scrofa
281177 Bos taurus
432392 Rattus norvegicus
448804 Canis lupus familiaris
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