Fused in Sarcoma (FUS) ELISA Kits

FUS encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. Additionally we are shipping FUS Antibodies (45) and FUS Proteins (2) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
FUS 2521 P35637
FUS 233908 P56959
Anti-Rat FUS FUS 317385  
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Top FUS ELISA Kits at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.156-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$875.60
Details
Mouse
  96 Tests Log in to see 15 to 18 Days
$875.60
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Cow
  96 Tests Log in to see 15 to 18 Days
$1,029.60
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More ELISA Kits for FUS Interaction Partners

Human Fused in Sarcoma (FUS) interaction partners

  1. The review describes the main physiological functions of FUS and considers evidence for each of the theories of amyotrophic lateral sclerosis pathogenesis.

  2. Authors used solid-state nuclear magnetic resonance methods to characterize the molecular structure of self-assembling fibrils formed by the LC domain of the fused in sarcoma (FUS) RNA-binding protein (show PTBP1 ELISA Kits). From the 214-residue LC domain of FUS (FUS-LC), a segment of only 57 residues forms the fibril core, while other segments remain dynamically disordered.

  3. Nuclear magnetic resonance spectroscopy demonstrates the intrinsically disordered structure of FUS's nearly uncharged, aggregation-prone, yeast prion (show PRNP ELISA Kits)-like, low sequence-complexity domain is preserved after phosphorylation.

  4. Long noncoding RNA SchLAH functions through interaction with fused in sarcoma protein (FUS).

  5. Results expand the spectrum of tumor types harboring EWSR1 (show EWSR1 ELISA Kits)/FUS-ATF1 (show AFT1 ELISA Kits) gene fusions to include a subgroup of conventional epithelioid malignant mesothelioma.

  6. Aggregation of FET proteins FUS, EWSR1, and TAF15 mediate a pathological change in amyotrophic lateral sclerosis. (Review)

  7. Focus on the recent advances on approaches to uncover the mechanisms of wild type and mutant FUS proteins during development and in neurodegeneration (review).

  8. FUS-induced reductions to ER-mitochondria associations and are linked to activation of glycogen synthase kinase-3beta (GSK-3beta (show GSK3b ELISA Kits)), a kinase already strongly associated with ALS (show IGFALS ELISA Kits)/FTD (show FTL ELISA Kits).

  9. Motor-neuron disease (MND (show CLN8 ELISA Kits))-linked RNA-binding proteins (RBPs), TDP-43 (show TARDBP ELISA Kits), FUS, and hnRNPA2B1 (show HNRNPA2B1 ELISA Kits), bind to and induce structural alteration of UGGAAexp. These RBPs suppress UGGAAexp-mediated toxicity in Drosophila by functioning as RNA chaperones for proper UGGAAexp folding and regulation of pentapeptide repeat translation.

  10. we analyzed fast axonal transport in larval motor neurons of Drosophila models of TARDBP (TDP-43 (show TARDBP ELISA Kits)), FUS and C9orf72. We also analyzed the effect of loss-of-function mutants of the Drosophila orthologs of TDP-43 (show TARDBP ELISA Kits) and FUS, TBPH and caz, respectively. The motor activities of larvae and adults in these models were assessed to correlate potential defects in axonal transport with locomotor deficits

Mouse (Murine) Fused in Sarcoma (FUS) interaction partners

  1. FUS-induced reductions to ER-mitochondria associations and are linked to activation of glycogen synthase kinase-3beta (GSK-3beta (show GSK3b ELISA Kits)), a kinase already strongly associated with ALS/FTD (show FTL ELISA Kits).

  2. our findings indicate that cytoplasmic FUS mislocalization not only leads to nuclear loss of function, but also triggers motor neuron death through a toxic gain of function within motor neurons.

  3. The data of this study support the notion that expression of cytoplasmically mislocalized FUS with compromised RNA-binding capacity causes particularly prominent and harmful FUS pathology in the mouse nervous system.

  4. These results highlight the pivotal role of FUS in regulating GluA1 (show GRIA1 ELISA Kits) mRNA stability, post-synaptic function and fronto-temporal lobar degeneration-like animal behaviors.

  5. these studies establish potentially converging disease mechanisms in amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy, with ALS-causative mutants acquiring properties representing both gain and loss of function.

  6. FUS/TLS depletion causes phenotypes possibly related to neuropsychiatric and neurodegenerative conditions, but distinct from ALS and ET, together with specific alterations in RNA metabolisms.

  7. It is associated with amyotrophic lateral sclerosis and its mutation causes accumulation of fus positive stress granules in neurons.

  8. Study provides evidence for loss of PRMT1 (show PRMT1 ELISA Kits) function as a consequence of cytoplasmic accumulation of FUS in the pathogenesis of amyotrophic lateral sclerosis, including changes in the histone code regulating gene transcription.

  9. our study provided evidence that a multistep process of FUS aggregation in the cell cytoplasm includes RNA-dependent and RNA-independent mechanisms.

  10. Activation of metabotropic glutamate (show GRIN1 ELISA Kits) receptors 1/5 in neocortical slices and isolated synaptoneurosomes increases endogenous mouse FUS and FUS(WT) protein levels but decreases the FUS(R521G) protein

FUS Antigen Profile

Antigen Summary

This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.

Gene names and symbols associated with Fused in Sarcoma (FUS) ELISA Kits

  • fused in sarcoma (FUS) antibody
  • fused in sarcoma (Fus) antibody
  • ALS6 antibody
  • D430004D17Rik antibody
  • D930039C12Rik antibody
  • ETM4 antibody
  • FUS/TLS antibody
  • Fus1 antibody
  • HNRNPP2 antibody
  • POMP75 antibody
  • Tls antibody

Protein level used designations for Fused in Sarcoma (FUS) ELISA Kits

75 kDa DNA-pairing protein , RNA-binding protein FUS , fus-like protein , fusion gene in myxoid liposarcoma , heterogeneous nuclear ribonucleoprotein P2 , oncogene FUS , oncogene TLS , translocated in liposarcoma protein , fusion, derived from t(12;16) malignant liposarcoma , hnRNP P2 , pigpen protein , protein pigpen , translocated in liposarcoma , fusion , pigpen , fusion (involved in t(12;16) in malignant liposarcoma) , 16) in malignant liposarcoma) , 16) malignant liposarcoma , fusion (involved in t(12 , fusion, derived from t(12

GENE ID SPECIES
2521 Homo sapiens
233908 Mus musculus
414144 Gallus gallus
280796 Bos taurus
317385 Rattus norvegicus
479778 Canis lupus familiaris
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