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an orphan G protein-coupled receptor that may have an important role in the central nervous system [RGD, Feb 2006].. Additionally we are shipping GPR37 Kits (8) and many more products for this protein.
Showing 5 out of 5 products:
Human Polyclonal GPR37 Primary Antibody for IHC (p), WB - ABIN390379
Yang, Nishimura, Imai, Takahashi, Lu: Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila. in Neuron 2003
Show all 3 references for ABIN390379
Human Polyclonal GPR37 Primary Antibody for IHC (p), WB - ABIN390380
Imai, Soda, Inoue, Hattori, Mizuno, Takahashi: An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin. in Cell 2001
Show all 3 references for ABIN390380
Data suggest that GPR37 regulates central nervous system myelination by controlling the transition from early-differentiated to mature oligodendrocytes.
Knocking-out GPR37 triggers anxiolytic-like effects and regulates hippocampal A2AR (show ADORA2A Antibodies)-mediated signaling.
These data show functional association between GPR37, prosaposin, and GM1 ganglioside in the plasma membrane.
GPR37 knockout mice show age and sex specific improvements in olfaction, increased anxiety and depression-like behaviors.
Upregulation of Pael-R in the substantia nigra pars (show EPRS Antibodies) compacta of mice by retrograde infection induced endoplasmic reticulum (ER) stress leads to death of dopaminergic neurons.
GPR37 associates with the dopamine transporter to modulate dopamine uptake and behavioral responses to dopaminergic drugs.
Data show that GPR37 overexpression can induce cellular autophagy, which may prevent the selective degeneration of GPR37-expressing neurons, as reported for Parkinson's and related neurodegenerative diseases.
Macroautophagy of the GPR37 orphan receptor (show NR1D2 Antibodies) and Parkinson disease-associated neurodegeneration
an orphan G protein-coupled receptor that may have an important role in the central nervous system
parkin-associated endothelin B-like receptor
, probable G-protein coupled receptor 37
, G protein-coupled receptor 37 (endothelin receptor type B-like)
, G-protein coupled receptor CNS1