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GPR56 encodes a member of the G protein-coupled receptor family. Additionally we are shipping GPR56 Antibodies (62) and GPR56 Kits (1) and many more products for this protein.
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Human GPR56 Protein expressed in Human Cells - ABIN2003727
Liu, Parker, Darby, Eyre, Copeland, Crawford, Gilbert, Sutherland, Jenkins, Herzog: GPR56, a novel secretin-like human G-protein-coupled receptor gene. in Genomics 1999
Show all 2 references for ABIN2003727
Gpr56 regulates oligodendrocyte development via interactions with Galpha12/13 and RhoA (show RHOA Proteins)
High GPR56 expression was significantly associated with high-risk genetic subgroups and poor outcome in patients with acute myeloid leukemia (show BCL11A Proteins) and identifies cancer stem cells with high repopulating potential.
Data suggest that agonist-induced signal transduction via either GPR56/ADGRG1 or BAI1 (show BAI1 Proteins)/ADGRB1 does not require conserved membrane-proximal stalk region of these proteins; ADGRG1 may participate in stalk-dependent and stalk-independent signaling.
Agonistic antibodies reveal the function of GPR56 in human glioma U87-MG cells
we knocked down GPR56 in cardiomyocytes and found that GPR56 promoted Ang II (show AGT Proteins)-induced cardiomyocyte hypertrophy and it contributed to PCBP2 (show PCBP2 Proteins) effects on cardiomyocyte hypertrophy
GPR56 and GPR110 (show GPR110 Proteins) are activated by exposure of a cryptic tethered agonist
These findings demonstrate that reduced expression of GPR56 in lung fibroblasts may be an important link with pulmonary fibrosis, playing a role in regulating some important fibroblast functions.
Data show that Gpr56, a G-coupled protein receptor, is required for hematopoietic cluster formation during transdifferentiation process in endothelial to hematopoietic cell transition (EHT (show CBFA2T2 Proteins)).
these data reveal a mechanism by which control of GPR56 expression pattern by multiple alternative promoters can influence stem cell proliferation, gyral patterning, and, potentially, neocortex evolution.
GPR56, MT1G (show MT1G Proteins), and RASSF1 (show RASSF1 Proteins) might be the potential methylation markers associated with acquired multidrug resistance of lung adenocarcinoma.
Loss of GPR56 is associated with abnormal muscle development.
GPR56 is a cell-autonomous regulator of oligodendrocyte development
Although GPR56 is abundantly and selectively expressed by primitive HSPCs, its high level expression is largely dispensable for steady-state and regenerative hematopoiesis.
These data illustrate a signaling pathway through GPR56 which regulates muscle hypertrophy associated with resistance/loading-type exercise.
adhesion G protein-coupled receptor (show GPR34 Proteins) GPR56-mediated RhoA (show RHOA Proteins) activation induced by collagen III stimulation
Role for TG2 (show TGM2 Proteins) in GPR56-mediated melanoma inhibition. The uncovered antagonistic relationship between GPR56 and TG2 (show TGM2 Proteins) proposes a mechanism by which extracellular matrix accumulation/crosslinking in tumors may be reversed.
GPR56 functions together with alpha3beta1 integrin in regulating cerebral cortical development.
We revealed that GPR56 is expressed in multiple cell types in the preplate, marginal zone, subventricular zone, and ventricular zone in the developing cerebral cortex
This gene encodes a member of the G protein-coupled receptor family. The protein contains 7 transmembrane domains and a mucin-like domain in the N-terminal region. The gene is implicated in the regulation of brain cortical patterning. The protein binds specifically to transglutaminase 2 in the extracellular space. Expression of this gene is downregulated in melanoma cell lines, and overexpression of this gene can suppress tumor growth and metastasis. Mutations in this gene result in bilateral frontoparietal polymicrogyria. Multiple transcript variants encoding different isoforms have been found for this gene.
G protein-coupled receptor 56
, G-protein coupled receptor 56-like
, 7-transmembrane protein with no EGF-like N-terminal domains-1
, G-protein coupled receptor 56
, secretin receptor
, serpentine receptor cyt28